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Original Article
Transforming growth factor-β promoted vascular endothelial growth factor release by human lung fibroblasts
Sang Uk Park, Joo Hwa Shin, Jae Won Shim, Deok Soo Kim, Hye Lim Jung, Moon Soo Park, Jung Yeon Shim
Clin Exp Pediatr. 2008;51(8):879-885.   Published online August 15, 2008
Purpose : The human lung fibroblast may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, which are important in airway remodeling. Vascular endothelial growth factor (VEGF) induces mucosal edema and angiogenesis. Thymus and activation regulated chemokine (TARC) induces selective migration of T helper 2 cells. We investigated whether human lung fibroblasts produced VEGF and TARC, and the...
Case Report
A case of idiopathic renal hypouricemia
Moon Hee Han, Sang Uk Park, Deok-Soo Kim, Jae Won Shim, Jung Yeon Shim, Hye Lym Jung, Moon Soo Park
Clin Exp Pediatr. 2007;50(5):489-492.   Published online May 15, 2007
Idiopathic renal hypouricemia is a disorder characterized by impaired urate handling in the renal tubules. This disease usually produces no symptoms, but hematuria, uric acid nephrolithiasis or acute renal failure may develop. A defect in the SLC22A12 gene, which encodes the human urate transporter, is the known major cause of this disorder. We describe a 10-month-old boy with idiopathic renal...
Partial Monosomy 21 Associated with Unbalanced t(10p;21q)
Bon Su Koo, Sang Uk Park, Jae Hong Park, Su Yung Kim
Clin Exp Pediatr. 1995;38(8):1146-1150.   Published online August 15, 1995
We experienced a case of partial monosomy 21 ina 9 year and 8 month old boy. He showed mental and growth retardation, others normal appearance except for low set malformed ears. Chromosomal analysis on Giemsa banding with high resolution showed unbalnaced translocation between 10 and 21 chromosomes and the deletion of short arm and centromere of chromosome 21. His karyotype...
G Deletion Syndrome II
Bon Su Koo, Sang Uk Park, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1995;38(2):240-244.   Published online February 15, 1995
We experienced a case of G deletion syndrome II in a 8 year and 1 month old boy. He showed mental retardation, microcephaly, high arched palate, low set malformed ears, epicanthal fold, thoracic deformity, tracheomegaly and two lumens of esophagus. Chromosomal study showed the deletion of long arm of chromosome 22, kariotypically he was depicted as 46, XY, 22q-. A brief...
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