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Case Report
A Case of Congenital Laryngeal Atresia with Single Umbilical Artery Who Required a Tracheotomy
Ho Sung Wi, Hey Sung Baek, Jae Won Oh, Myung-Kul Yum, Yong Joo Kim, Soo Jee Moon, Kyung Tae, Chang-Ryul Kim
Clin Exp Pediatr. 2005;48(5):557-560.   Published online May 15, 2005
Congenital laryngeal atresia is a rare cause of airway obstruction that is almost always lethal within a few minutes after birth. Therefore congenital laryngeal atresia should be diagnosed in the prenatal period. If not, it should be considered in newborn infant with life-threatening symptoms at birth such as cyanosis and dyspnea that need emergent procedures like a tracheotomy. We report...
Original Article
Repetition of Apoptosis Induced by Amiloride Derivatives in Human Umbilical Vein Endothelial Cells
Kyu Chang Park, Kyu Sang Park, Soo Jee Moon
Clin Exp Pediatr. 2003;46(1):56-66.   Published online January 15, 2003
Purpose : Human umbilical vein endothelial cells(HUVECs) play an important role in regulating blood flow by releasing vasoactive substances. It has been reported that endothelial impairment and dysfunction might be a primary cause of placental vascular disease, which is manifested clinically as preeclampsia in mother and intrauterine growth restriction in fetus. Furthermore, the frequency of apoptotic changes is increased in...
Case Report
49, XXXXY Syndrome with Multicystic Kidney in a Neonate
Eun Young Park, Soo Jee Moon
Clin Exp Pediatr. 2001;44(6):714-717.   Published online June 15, 2001
The 49, XXXXY Klinefelter variant is distinctive; classic findings include mental retardation, hypogonadism and radioulnar synostosis. Its incidence is estimated to be 1/80,000 to 1/100,000 male births. We report a case of 49, XXXXY syndrome confirmed by chromosomal study in neonatal period, whose clinical features included a coarse face, short neck, micropenis, and other multiple minor anomalies including simian creases....
Original Article
A Comparative Study of the Effects of Intravenous Indomethacin and Oral Mefenamic Acid in the Treatment of Premature Infants with Patent Ductus Arteriosus
Hae Jung Park, Yoon Suk Jung, Nam Soo Kim, Chang Ryul Kim, Hyuk Kim, Soo Jee Moon
Clin Exp Pediatr. 2001;44(1):32-39.   Published online January 15, 2001
Purpose : For the management of patent ductus arteriosus(PDA) in premature infants, fluid restriction, correction of anemia, mechanical ventilation, diuretics, and surgery have been used, and the closure rate of PDA has improved significantly since the introduction of indomethacin and mefenamic acid as pharmacologic treatments of PDA. We studied to evaluate and compare the therapeutic effects of indomethacin and mefenamic...
Assessment by Question-Naire of Disease Status of the Pupils in Two Primary Schools in Seoul
Jae Kyung Choi, Nam Soo Kim, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1993;36(7):994-1001.   Published online July 15, 1993
We studied the disease status by question-naire in Seoul of the pupils in two primary schools on May, 1991 and carried out statistical analysis of their results. The following results were observed: 1) Total number of answered pupil was 2330;1103 were male and 1227 were female and the ratio of male to female was 1:1.1. Average age was 9.27 years. 2) Number of...
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
A clinical study on twin.
Ho Joon Im, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1991;34(5):621-628.   Published online May 31, 1991
Among the total of 17,991 newborns delivered at Hanyang University Howpital from January 1980 to December 1989, a clinical study was performed on 277 twin pregnancies. The results of the study were as follows: 1) The incidence of twins was 1:64.9. 2) The average male-female sex ratio of twins was 1:1.1, total same sex pairs rate was 79.4% (male-male & female-female) and different sex rate was 20.6%. 3) The...
Comparison between Treatment with Aspirin Alone and the Combined Treatment with Aspirin and Intravenous gamma-Globulin in Kawasaki Disease.
Sang Yoon Ahn, Sun Yang Hong, Nam Soo Kim, Ha Baik Lee, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1990;33(10):1380-1387.   Published online October 31, 1990
Out of a total of 140 children hospitalized with the diagnosis of Kawasaki disease at the Depart- ment of Pediatrics, Hanyang University Hospital during the period of 9 years from July 1980 to July 1989, 68 cases were subjected to echcocardiographic examination at 10 to 15 days after the onset of illness, and these 68 cases were divided into two groups according the...
A clinical and Statistical study of Meconium Stained Baby: A Two Year Prospective Study.
Joo Hyun Ham, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1990;33(9):1173-1179.   Published online September 30, 1990
Among the total of 2,483 Newborns delivered at Hanyang University Hospital from January 1987 to December 1988, a clinical study was performed of meconium stained baby. The results are summerized as follows: 1) The incidence of meconium staining was 13.4% (333 cases) in total 2,483 newborns. 2) In the groups that the birth weight is 2501 ~ 4000 gm and up to 4001 gm, the incidence...
A Case of Recessive Epidermolysis Bullosa Dystrophica.
Young Tae Kim, Hak Won Kim, Seung Hee Oh, Soo Jee Moon, Chan Kum Park
Clin Exp Pediatr. 1990;33(8):1111-1116.   Published online August 31, 1990
Epidermolysis Bullosa Dystrophica (EBD), a subtype of epidermolysis bullosa, is a rare inherited disease characterized by induction of blisters and erosions in skin and mucous membrane by minor or no trauma, which heal with scar formation. Clinical course is more severe in recessive type of EBD than dominant type. We have experienced a case of recessive EBD in a one day old female patient...
The Clinical Observation on Mucocutaneous Lymph Node Syndrome.
Sang Yun Ahn, Ja Wook Koo, Ha Baik Lee, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1990;33(2):196-204.   Published online February 28, 1990
The one-hundred-forty nine children with mucocutaneous lymph node syndrome who were diagnosed and treated through admission at the Department of Pediatrics, Hanyang University Hospital from July 1977 to January 1989, were investigated for clinical patterns and laboratory , correlations. The results are as follows: 1) Most patients (84.5%) were under 4 years of the age. 2) Boys were more prevalent than girls, as a ratio of 1.9:1. 3) Seasonal incidence...
Citrobacter Freundii Meningitis in A Newborn.
Sang Yun Ahn, Yong Joo Kim, Seung Hee Oh, Soo Jee Moon
Clin Exp Pediatr. 1989;32(12):1732-1735.   Published online December 31, 1989
Citrobacter freundii have been reported infrequently as a cause of meningitis. And, among bacteria that cause meningitis, Citrobacter is unique in its propensity to produced brain abscess. But the pathogenesis of Citrobacter meningitis and brain abscess in humans is unknown. The high prevalance of brain abscess in infants with Citrobacter meningitis mandates cranial computed tomography in every case. The morbidity and mortality rates associated with...
A Clinical Study of Hospitalized Neonates with Fever.
Youn Mo Ahn, Chang Ryul Kim, Woo Gill Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(11):1437-1444.   Published online November 30, 1988
Life-threatening bacterial infections such as meningitis, septicemia, and pneumonia in the neonates are more common than at any other time in life and signs of these infections are often subtle and non-specific. Because of these factors, the patient who has persistent fever will almost always be started on parenteral antibiotics immediately following evaluation. On the other hand there is also evidence that the hospital...
Lateral Ventricular Indices in tuberculous Meningitis.
Ja Wook Koo, Hang Bo Cho, In Joon Seol, soo Jee Moon, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1988;31(8):984-991.   Published online August 31, 1988
Computed tomography is a very valuable method by which the pathogenic evolution of tuberculous meningitis may be followed, thereby facillitating its differential diagnosis and controlling the effi- ciency of therapy, and assessing the degree of hydrocephalus. Fifteen cases of clinically proven intracranial tuberculosis were studied by lateral ventricular indices of brain computed tomography in our hospital during last 3 years. The results were as follows: 1)...
Statistical Assessment on Chromosomal Aberrations observed on Childhood.
Seong Ho Kim, Jeh Hoon Shin, Soo Jee Moon, Hahng Lee, KeunSoo Lee, Youl Hey Cho, Myung So Ryu, Young Kyun Paik
Clin Exp Pediatr. 1988;31(8):977-983.   Published online August 31, 1988
Chromosomal studies were carried out in 730 patients at the Dept, of Pediatrics and Genetics, Hanyang University Hospital, form December 1979 to April 1986. A statistical assessment was carried out in 244 cases who have chromosomal aberrations. The following results were obtained: 1) Chromosomal aberrations were observed in 244 cases among 730 cases, so the propotion of chromosomal aberrations was 33%. 2) Age distribution revealed 53% of chromosomal...
A Prospective Study of Urinary beta2 -Microglobulin in Infants with Meconium-Stained Amniotic Fluid.
Sung Oh Kim, Jeh Hoon Shin, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1988;31(8):968-976.   Published online August 31, 1988
We studied prospectively whether events that result in meconium staining may be associated with additional abnormalities that are not clinically apparent associated by measurements of urinary concentrations of β₂-microglobulin indicating renal proximal tubular functions. Among 61 fullterm, healthy neonates delivered at Hanyang University Hospital during the period of September 1986 through April 1987, urinary concentration of β₂-microglobulin and creatinine were measured during the immediate perinatal...
Statistical observation for Congenital Malformation.
Sung Oh Kim, Soon Sup Jang, Jeh Hoon Shin, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1988;31(2):161-166.   Published online February 28, 1988
Although perinatal diagnosis and management has been developed rapidly in recent years, congeni- tal malformations are known to have remained largely unchanged in incidence of infants being delivered. In spite of its clinical significance and physician’s every effort to exclude the possible factors of congenital malformations by perinatal care, there is still no enough statistical data of congenital malformtions in Korea. So, we surveyed to...
The Case of Persistent Pulmonary Hypertension of the New born.
Sung Oh Kim, Soo Yup Lee, Kyoo Hwan Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(1):128-133.   Published online January 31, 1988
Persistent pulmoanry hypertension of the newborn (PPHN) is a syndrome consisting of severe hypoxemia and pulmoanry hypertension that appears within hours of birth. The essential pathophysiologic features of this syndrome is pulmonary artery hypertension causing right-to-left shunt through the patent ductus arteriosus or foramen ovale or both and clinically manifested by central cyanosis and respiratory distress. We recently have experienced 20 hour old female and...
A Case of Potter Syndrome Syndrome Accompanied with Partial Agenesis of Corpus Callosum.
Soon Sup Jang, Byung Chun Suh, Kyoo Hwan Rhee, Soo Jee Moon, Keun Soo Lee, Byung Tae Park, Eun Kyung Hong
Clin Exp Pediatr. 1987;30(11):1287-1293.   Published online November 30, 1987
We have experienced a case of Potter syndrome recently. He was a newborn infant who suffered from severe respiratory distress soon after birth. His face was characterized by facies renalies and chest X-ray film revealed bilateral pneumothorax. Anuria since birth and findings of abdominal ultrasonography strongly suggested bilateral renal agenesis. Severe respiratory acidosis was progressed in spite of proper management and died at 11...
Case Report
Intermittent Hydronephrosis.
Hong Kun Kim, Woo Gill Lee, Soo Jee Moon
Clin Exp Pediatr. 1987;30(7):805-811.   Published online July 31, 1987
Episodic flank or abdominal pain with or without nausea and vomiting is most common manifesta- tion of intermittent hydronephrosis. Between episodes of pain, the patient may be asymptomaitc and intravenous urogram usually will be normal. This condition is diagnosed by intravenous urogram or ultrasonogram taken either during episodes of pain or after hydronephrosis precipitated by use of duretics or ingestion of alcoholic beverage, particulary...
A Case of Holoprosencephaly.
Byung Chun Suh, Soon Sup Jang, In Joon Seol, Soo Jee Moon, Chong Moo Park, Seok Chol Jeon
Clin Exp Pediatr. 1987;30(6):695-700.   Published online June 30, 1987
We experienced a case of holoprosencephaly with extracranial abnormalities, including orbital hypotelorism, median cleft lip without philtrum, flat nasal bridge, flat face, and microcephaly and with a karyotype, 46 XX, 22p+. The diagnosis was confirmed by brain CT scan & brain ultrasonography, and the findings were compatible with an alobar type of holoprosencephaly. The patients died at 26 days of age. A brief review of...
Original Article
Clinical Study of Childhood Accident.
Tae Jin Park, Sung Ryong Hyun, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1986;29(9):988-998.   Published online September 30, 1986
Since the advent of various antibiotics and wide application of various preventive measure, the childhood mortality due to infectious disease has been declined conspiciously. However, childhood accident has been increasing in recent years and now a days it ranks the leading cause of childhood mortality and morbidity. Because most of the accident are unpredictable and occur suddenly, those result they occupy...
Case Report
A case of Sacrococcygeal Teratoma.
Seung Jae Yang, Kwang Nam Kim, In Joon Seol, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1986;29(5):564-569.   Published online May 31, 1986
We exprienced a case of sacrococcygeal teratoma in newborn girl with massive intraabdominalfextensioii and small caudal mass, which is relative rare.
Original Article
Clinical Studies on Neonatal Jaundice and Exchange Transfusion.
Byoung Hun Kim, Soo Yup Lee, Jeh Hoon Shin, Kyu Hwan Lee, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1986;29(5):535-542.   Published online May 31, 1986
Jaundice occurs rather frequently in neonatal period, and yet the irreversible complication, kernicterus, may occur in severe cases with pathologic jaundice, from which the patients are at high risk for mental retardation, cerebral palsy, and even death. To prevent this complication, aggressive measures have been used for the neonatal janudice, such as phototherapy and exchange transfusion. Exchange transfusion has been...
Clinical Study on Anemia in Neonatal Period.
Jin Young Lee, Hong Kun Kim, Woo Gil Lee, Soo Jee Moon, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1986;29(5):525-534.   Published online May 31, 1986
Neonatal period is marked with constantly changing hematologic process due to a number of physiologic and pathologic factors, and with risk of underdiagnosis or misdiagnosis of anemia of various causes. Therefore, prompt diagnosis of anemia and accurate identification of its underlying causes would be essential to arrive at the appropriate management and to avoid occasional serious complications. 104 full term...
The Present Status of Infants Feeding in Korea.
Gyoung Hee Kim, Keun Lee, Choong Hee Kim, Keun Soo Lee, Sang Man Shin, Dong Gawn Han, Soo Jee Moon
Clin Exp Pediatr. 1985;28(10):960-966.   Published online October 31, 1985
A Survey on the present status of infants feeding in Korea was carried out during the period form July to September of 1984.
Nutrition of Low Birth Weight Infants and Infant Formula for Low Weight Infants.
Gyoung Hee Kim, Choong Hee Kim, Soo Jee Moon, Sang Man Shin, Dong Gawn Han, Keun Lee, Keun Soo Lee
Clin Exp Pediatr. 1985;28(10):953-959.   Published online October 31, 1985
A Clinical Study on Reye's Syndrome.
Hye Sun Jung, Seong Ryong Hyon, Ha Baik Lee, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1985;28(8):783-794.   Published online August 31, 1985
Ninety three cases of Reye's Syndrome were admitted to pediatric ward of Hanyang University Hospital during 6 year period from January 1979 to December 1984. The following results were obtained; 1)The peak age incidence was under 1 year of age. The sex incidence revealed male predominance with sex ratio 1.6 to 1(M : F). 2)The peak seasonal incidence was noted in...
The Use of Pedialyte(R) RS(oral electrolyte solution) and Isomil(R) in the Treatment of Nonbacterial Acute Infantile Gastroenteritis.
Keun Soo Lee, Seung Jae Yang, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1985;28(4):330-339.   Published online April 30, 1985
40 Pediatric patients with mild to moderate dehydration due to nonbacterial acute infantile gastroenteritis were admitted to the study. On admission to the hospital, each patient was assigned at random either to the Pedialyte® RS+Isomil®(Group A), or to intravenous fluid+cow's milk-based formula (Group B). Each group consisted of 20 patients. There were no significant differences between the two group as...
Neonatal Campylobacter enteritis.
Tae Jin Park, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1984;27(10):965-970.   Published online October 31, 1984
During the period from Jan. 1982 to July 1983, we experienced 54 cases of neonatal enteritis caused by Campylobacter fetus subspecies jejuni at the newborn nursery, Hanyang University Hospital. All Cases were under 3 weeks of age and no significant difference was seen in sex ratio. Notable clinical symptoms and signs in order of frequency were diarrhea, fever, jaundice, diminished...
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