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Original Article
A Five-year Epidemiologic Study of Childhood Leukemia in Busan City, 1996 to 2000
Jae Hoon Moon, Soon Yong Lee, Jong Beom Sinn, Jae Sun Park, Young Ho Lee, Young Tak Lim, Su Eun Park
Clin Exp Pediatr. 2003;46(10):972-976.   Published online October 15, 2003
Purpose : For the control of childhood leukemia, of which the mortality is still high, the basic data for the incidence has a great importance. The authors analyzed the data from 133 new patients with childhood leukemia between 1996-2000 in Busan, Korea. Methods : The data were obtained from 133 new cases(87 males and 46 females from 0 to 15 years...
Prophylactic Treatment of Anemia of Prematurity with Recombinant Human Erythropoietin and High Doses of Iron
Young Ho Lee, Ahn Hong Choi, Soon Yong Lee, Jeong Sook Park, Bong Keun Choi, Hyoung Shim Chang
Clin Exp Pediatr. 1997;40(3):361-367.   Published online March 15, 1997
Purpose : We conducted randomized study to determine whether high doses(6mg/kg/ day) of iron would exert a more supplemental effect than low doses(3mg/kg/day), and which regimen of recombinant human erythropoietin(rHuEPO) and iron would be more beneficial in the prophylactic treatment of anemia of prematurity. Methods : We randomly assigned 38 sick premature infants who were more likely than symptom-free premature infants requiring erythrocyte transfusions for...
Case Report
A Case of Neurofibromatosis with Multiple Neurofibromas on Mesentery
Pil Geung Hwang, Sun Young Park, Tae Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1997;40(2):270-273.   Published online February 15, 1997
Neurofibromatos is originally described by von-Recklinhausen in 1882, is often depicted as a chronic progressive hereditary disease characterized by pigmentation of the skin, cutaneus lesions, and numerous tumors developing in association with elements of both the central and peripheral nervous tissue. Mesenteric involvements in neurofibromatosis are very rare in childrens. We experienced a case of neurofibromatosis with multiple neurofibromas on mesentery in...
Original Article
Diagnostic Significance of Urinary Growth Hormone Measurement in Patients with Growth Hormone Deficiency
No Hyun Kim, Woo Yeong Chung, Soon Yong Lee
Clin Exp Pediatr. 1995;38(8):1124-1131.   Published online August 15, 1995
Purpose : To investigate the diagnostic significance of urinary growth hormone measurement and compare with the urinary GH values in different methods of urine collection, this study was performed in patients with short stature. Methods : Measurement of urinary GH excretion was performed in 9 children with complete growth hormone deficiency (GCD), in 19 children with partial growth hormone deficiency (GPD)...
A Comparative Study o fIntavenous Methylprednisolone Dosage for Treatment of Children with Acute Idiopathic Thrombocytopenic Purpura
Eun Ju Shin, Yeong Jae Song, Woo Yeong Chung, Tae Gyu Hwang, Soon Yong Lee
Clin Exp Pediatr. 1995;38(4):513-519.   Published online April 15, 1995
Purpose : It is well known that use of intranenous methylprednisolone(IVMP)for the patients with idiopathic thrombocytopenic purpura(ITP) is not only as effective as use of intravenous gammaglobulin to mincrease platelets quickly, but also the former is less expensive than the latter. As the adequate dosage of IVMP has not been fully elucidated, we have tried to determine it. Methods : The...
Significance of Urinary Interleukin 6 Level in Mesangial Proliferative Glomerulonephritis in Children
Byeong Ho Kang, No Hyun Kim, Woo Yeong Chung, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1994;37(7):900-905.   Published online July 15, 1994
By animal experiments in rat, it has been known that Interleukin-6(IL-6) is secreted from renal mesangial cells and is an autocrine growth factor for the proliferation of mesangial cells. According to these facts, several studies have been tried for its clinical usefulness by measuring their serum or urinary IL-6 in glomerulonephritis patients with mesangial proliferation. The authors measured urinary IL-6...
A Clinical Study on Childhood Leukemia
Joo Huh, Jong Bum Shin, Soon Yong Lee
Clin Exp Pediatr. 1994;37(5):655-665.   Published online May 15, 1994
Clinical analysis of 170 patients with childhood leukemia was made, who were admitted to the department o Pediatrics, Pusan Paik Hospital, Inje University, College of Medicine during 10 years from 1981 to 1990. The results were as follows: 1) The annual number of the patients with childhood leukemia was in the range of 6~25 cases. And the annual rate of the...
Urinary Vitamin C Loading Test and Therapeutic Effect of Vitamin C in Children with Idiopathic Recurrent Epistaxis
In Soon Park, Woo Yeong Chung, Soon Yong Lee
Clin Exp Pediatr. 1993;36(2):266-272.   Published online February 15, 1993
Recurrent epistaxis is not one of rare symptoms in children, the well-known causes of which are anatomical abnormalities of nasal cavity and systemic bleeding tendency. But, in the majority of cases of recurrent epistasix, it is usually very difficult to find out their underlying causes, so that the treatment is only symptomatic control of nasal bleeding whenever epistaxis occurs, but...
Case Report
A Case of Prune Belly Syndrome in Female
Zu Heo, Eun Joo Shin, Woo Yeong Chung, Soon Yong Lee
Clin Exp Pediatr. 1992;35(10):1454-1458.   Published online October 15, 1992
We experienced a case of prune belly syndrome in a 2 days old female with deficient abdominal wall musculature and urinary tract anomalies which composed of bilateral multicystic kidney, left vesicoureteral reflux and megaureter with kinking in appearance and marked distended bladder. On ultrasonographic examination, there were no abnormalities in uterus, vagina and overies. A review of literatures was also presented briefly.
Original Article
An effect of IV methylprednisolone in acute idiopathic thrombocytopenic purpura.
Jin Kuk Kim, Kyeong Hee Hong, Tae Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1991;34(9):1240-1245.   Published online September 30, 1991
The major goal in the treatment of acute idiopathic thrombocytopenic purpura (ITP) is to increase the platelet count above the critical level of 20,000/mm3 to avoid intracranial hemorrhage. We have treated eighteen children with acute ITP whose platelet count were below 20,000/mm3 at initial diagnosis. Thirteen of 18 patients (group A) received IV methylprednisolone (IVMP) 10〜20 mg/kg/day for 5 days from the day of...
A case of Weber-Christian disease.
Doo Kweon Kim, Sang Jo Park, Tae Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1991;34(8):1157-1162.   Published online August 31, 1991
Weber-Christian disease is a relapsing febrile nodular nonsuppurative inflammation of the subcuta- neous fat tissue. We experianced a case of Weber-Christian disease. The patient was a 10-year-old girl with the complaints of fever, malaise and erythematous painful nodules on extremities, trunk and back. The diagnosis was based on the clinical pictures and the histologic findings. Oral prednisolone therapy was tried and the response occurred...
A case of histiocytic necrotizing lymphadenitis.
Jin Kuk Kim, Jong Bum Shin, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1991;34(4):582-586.   Published online April 30, 1991
We experienced a case of histiocytic necrotizing lymphadenitis in a 10-year old male child with complaints of high fever and painful swelling on right cervical area for 11 days. The diagnosis was based on histopathologic findings of right cervical lymph node, clinical features and laboratory findings. A review of literatures was also presented briefly.
A Case of Aplastic Anemia Following hepatitis.
Gae Soon Yeo, Doo Kweon Kim, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1990;33(6):864-869.   Published online June 30, 1990
We experienced a case of aplastic anemia following hepatitis in a 4-year-old girl. Pancytopenia was developed during the convalescent period of hepatitis, and it was getting worse, while serial data of liver function test showed improvement. We tried a methylprednisolone pulse therapy, and about 7 months after treatment the CBC findings returned completely normal. She has enjoyed her healthy life during follow-up of over 2...
Immunomodulation Therapy in Children with Aplastic Anemia.
Won Suk Suh, Ki Sik Min, Woo Gun Choi, Hack Ki Kim, Kyoung Sn Lee, Soon Yong Lee
Clin Exp Pediatr. 1990;33(2):170-177.   Published online February 28, 1990
Thirty patients with aplastic anemia(fifteen severe aplastic anemia and fifteen moderate aplastic anemia) treated with antilymphocyte globulin and cyclosporin A as a kind of immunomodulation therapy were studied by analysing hematologic reseponses and complications. The results were as follows; 1) Nineteen out of thirty patients (63.3%) treated with anti lymphocyte globulin plus cyclosporin A showed responses (complete response of 33.3%, partial response of 30.0%). 2) Hematologic responses according...
A Case of Measles Hepatitis.
Sang Hoo Lee, Gae Soon Yeo, Sun Bock Suh, Moo Young Oh, Soon Yong Lee
Clin Exp Pediatr. 1989;32(12):1740-1743.   Published online December 31, 1989
In the pediatric age, hepatitis has rarely been recognized as a complication of measles infection. We have experienced a case of hepatitis in a 6-year-old boy with prominent clinical features of measles. A brief review of literatures was made.
A Case of Myelodysplatic Syndrome.
Sun Bok Suh, Chang Ok Soh, Sang Hoon Lee, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1989;32(9):1314-1319.   Published online September 30, 1989
We have experienced a case of myelodysplastic syndrome (RAEB) in an 11-year-old boy with the complaints of pallor and petechiae for 1 month. After diagnosis, improvement was remarkable with chemotherapy of low dose cytosine arabinoside but the RAEB was transformed to acute myeloblastic leukemia 4 months after treatmemt. Anti-leukemic therapy was tried but induction of remission was failed and he was died of sepsis...
A Case of Wilson Disease.
Cheol Soo Dan, Sang Hoon Lee, Woo Yeong Chung, Soon Yong Lee, Jong Eun Joo, Hye Jae Cho
Clin Exp Pediatr. 1988;31(11):1502-1508.   Published online November 30, 1988
We have experienced a case of Wilson disease manifesting chronic hepatitis. The patient, 10-year-old boy, has shown elevated SGOT and SGPT levels since 5 years ago, but no other specific symptoms of Wilson disease. His younger sister died of fulminant hepatitis (absence of hepatitis A or B markers) at the age of eight. The diagnosis was based on the characteristic laboratory data and the...
An Analysis of Incidence Requiring Resuscitation in Full-Term Cesarean Delivered Infants.
Ewi Seong Seo, Cheol Soo Dan, Woo Yeong Chung, Soon Yong Lee, Goo Hwa Je
Clin Exp Pediatr. 1987;30(7):722-726.   Published online July 31, 1987
An analysis of incidence requiring resuscitation in relation to the indication of cesarean section in full-term deliveries were carried out retrospectively during 24 months from January 1984 to December 1985. The results obtained were as follows. 1) The overall incidence of cesarean delivery was 17.2% (397 cases out of 2,308 total deliveries) and the rate of full-term was 77.6% of total cesarean deliveries. 2) Among full-term cesarean delivered...
A Case of Congenital Anterior Urethral Diverticulum.
Young Ho Lee, Gyu Jeon Song, Woo Yeong Chung, Moo Young Oh, Soon Yong Lee
Clin Exp Pediatr. 1987;30(4):431-434.   Published online April 30, 1987
Recently, we experienced a case of congenital anterior urethral diverticulum in 8-month-old male infant. He had recurrent fever and urinary dribbling for 3 months. The diagnosis was based on radiologic and cystoscopic findings, and anterior urethral diverticulectomy was performed. A review of literatures was also presented briefly.
Case Report
3 Cases of Congenital Hypothyroidism.
Chul Hwan Park, Moo Young Oh, Tae Gyu Hwang, Soon Yong Lee, Yeon Soon Kim
Clin Exp Pediatr. 1987;30(3):320-326.   Published online March 31, 1987
We observed 3 cases of congenital hypothyroidism. A 43-day-old girl, a 372-month-old boy and a 5-year-old girl were presented. The causes were thyroid agenesis of case I, defective TSH receptor (suspect) of case II and undetermined in case III respectively. The diagnosis was made by clinical manifestations, thyroid function test, A brief review of literatures was made.
A case of Infectious Mononucleosis.
Hak Jun Ko, Eui Bon Koo, Tai Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1986;29(1):113-113.   Published online January 31, 1986
A case of infectious mononucleosis in a 22-month-old male was reported. The diagnosis was made chiefly on the clinical findings and the typical findings of peripheral blood smear. A review of literatures was presented briefly.
Three Cases of Diebetes Insipidus.
Eue Bon Koo, Hak Jun Go, Tai Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1986;29(1):88-94.   Published online January 31, 1986
We reported three cases of Diabetes Insipidus which were characterized by polyuria and polydipsia. One case was idiopathic and two cases were associated with tuberculous meningitis and pinealoma respectively. Water restriction test and hypertonic saline infusion test revealed little change in urine volume and specific gravity but good response to intramuscular injection of pitressin in all of the three cases....
A Case of Sacral Agenesis.
Cheol Lee, Byung Uk Park, Tae Gyu Hwang, Soon Yong Lee
Clin Exp Pediatr. 1986;29(1):79-83.   Published online January 31, 1986
Sacral agenesis is a rare congenital anomaly of the lower vertebral column which usually produces lower urinary tract dysfunction. The authors have reported a case of sacral agenesis which was found in a l-year-4-month old girl, who was born of a diabetic mother and had been suffered from recurrent urinary tract infection. A brief review of literatures was made.
A Case of Combined Esophageal Atresia and Duodenal Atresia.
Ju Yeong Seo, Cheol Lee, Woo Yeong Chung, Soon Yong Lee, Yeon Soon Kim
Clin Exp Pediatr. 1985;28(9):912-915.   Published online September 30, 1985
We experienced a case of combined esophageal atresia without tracheoesophageal fistula and duodenal atresia. Choanal Atresia was also associated. The diagnosis was confirmed by prenatal ultrasonography, abdominal radiography and autopsy. A review of literatures was also presented briefly.
A Case of Endothelial Sinus Tumor of the Vagina.
Moo Young Oh, Chul Hawn Park, Hyun Gi Jung, Tai Gyu Whang, Chul Ho Kim, Soon Yong Lee, Suk Hee Hong
Clin Exp Pediatr. 1984;27(11):1135-1140.   Published online November 30, 1984
We presented a case of endodermal sinus tumor of the vagina in a 17 month-old female baby with the complaints of vaginal blee4ing and difficulty of urinations. Diagnosis was confirmed by the biopsy findings of the tumor tissue from the vagina and the elevated serum alpha-fetoprotein. A review of related literatures was made.
A Case of Congenital Monocytic Leukemia.
Woo Yeong Chung, Eue Bon Koo, Hak Jun Ko, Tai Gyu Whang, Soon Yong Lee, Yeon Soon Kim
Clin Exp Pediatr. 1984;27(10):1022-1027.   Published online October 31, 1984
We experienced a case of congenital monocytic leukemia in a 25 day old female newborn infant. She was admitted because of petechiae, abdominal distension and skin nodules scattered on. whole body. Diagnosis was confirmed with findings of CBC, bone marrow aspiration and cytochemistry. A review of literatures was also presented.
A Case of Neurofibromatosis associated with Pseudoarthrosis of the Ulna.
Ju Yeong Seo, Woo Yeong Chung, Soon Yong Lee, Kil Hyun Kim, Yeon Soon Kim
Clin Exp Pediatr. 1984;27(5):516-520.   Published online May 31, 1984
We experienced a case of neurofibromatosis associated with pseudoarthrosis of the ulna in a 5-year-old boy. He had multiple cafe-au-lait spots, neurofibromas, and macrocranium with positive family history. A review of literatures was also presented briefly.
A Case of Hepatic Hemangioendothelioma.
Ki Tae Kim, Heon Kyung Lee, Soon Yong Lee, Young Sik Park, Kil Hyun Kim, Yeon Soon Kim
Clin Exp Pediatr. 1984;27(4):395-400.   Published online April 30, 1984
We experienced a case of hepatic hemangioendothelioma in a 21-day-old girl who had a large mass in the left upper quadrant of abdomen. The diagnosis was confirmed by laparatomy and histological finding. A review of the related literatures was also made.
A Case of Patent Urachus.
Heon Kyung Lee, Ki Tae Kim, Woo Yung Chung, Soon Yong Lee, Yung Sik Park, Yeon Soon Kim
Clin Exp Pediatr. 1984;27(1):89-92.   Published online January 31, 1984
We present a case of patent urachus in a newborn male baby with the symptom of a leakage of urine from the umbilicus. Diagnosis was made radiologically and it was surgically removed successfully. A brief review of related literatures is also presented.
A Case of Hereditary Spherocytosis.
Eui Lim Choi, Chul Hwan Park, Tae Gyu Hwang, In Soon Park, Soon Yong Lee
Clin Exp Pediatr. 1983;26(11):1120-1124.   Published online November 30, 1983
We observed a case of hereditary spherocytosis who was a 4-month-old boy with the chief complaints of jaundice and pallor. Evidence of the same disease was also found in the patient` s father who had never been symptomatic. Diagnosis was made by presence of spherocytes in peripheral blood smear, osmotic fragility- test and autohemolysis test. A brief review of literatures was made.
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