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Original Article
Serum procalcitonin as a diagnostic marker of neonatal sepsis
In Ho Park, Seung Hyun Lee, Seung Taek Yu, Yeon Kyun Oh
Clin Exp Pediatr. 2014;57(10):451-456.   Published online October 31, 2014

We evaluated serum procalcitonin (PCT) as a diagnostic marker of neonatal sepsis, and compared PCT levels with C-reactive protein (CRP) levels.


We retrospectively reviewed the medical records of 269 neonates with a suspected infection, admitted to Wonkwang University School of Medicine & Hospital between January 2011 and December 2012, for whom PCT and CRP values had been obtained. Neonates were categorized...

Case Report
A case of severe transient hyperammonemia in a newborn
Min Woo Hwang, Seung Taek Yu, Yeon Kyun Oh
Clin Exp Pediatr. 2010;53(4):598-602.   Published online April 15, 2010
Transient hyperammonemia in a newborn is an overwhelming disease manifested by hyperammonemic coma. The majority of affected newborns are premature and have mild respiratory syndrome. The diagnosis may be difficult to determine. This metabolic disorder is primarily characterized by severe hyperammonemia in the postnatal period, coma, absence of abnormal organic aciduria and normal activity of the enzymes of the urea...
Original Article
Comparison and analysis of the effectiveness to high dose of aspirin and ibuprofen in acute phase of Kawasaki disease
Seung-woon Keum, Yeon Kyun Oh, Jong Duck Kim, Seung-taek Yu
Clin Exp Pediatr. 2009;52(8):930-937.   Published online August 15, 2009

Purpose:We evaluated the effectiveness of treatment and cardiac complications of replacing a high dose of aspirin with a high dose of ibuprofen for children in acute phase of Kawasaki disease. We also analyzed the possibility of replacing a high dose of aspirin with a high dose of ibuprofen to prevent complications such as Reye s syndrome caused by aspirin. Methods:One hundred eight children...
Clinical factors causing hyperbilirubinemia in patients with Kawasaki disease
Kyung Hee Moon, Ok Ran Kim, Seung Taek Yu, Myung Eun Hong, Chang Woo Lee, Du Young Choi, Yeon Kyun Oh, Jong Duk Kim, Hyang Suk Yoon
Clin Exp Pediatr. 2007;50(1):52-55.   Published online January 15, 2007
Purpose : Hyperbilirubinemia, jaundice and gallbladder hydrops are unusual manifestations of Kawasaki disease (KD). In this case, abdominal pain, anorexia and abdominal distension may follow eventfully. We reviewed the clinical and laboratory data to investigate the causative factors of hyperbilirubinemia in patients with KD. Methods : Two-hundred eighty two children diagnosed and hospitalized with KD were identified by searching patients' charts....
Case Report
A Case of Intussusception Caused by Meckel's Diverticulum in a Newborn
Seung Taek Yu, Yeon Kyun Oh, Won Churl Park, Eun A Kim, Chang Woo Lee, Hyang Suk Yoon
Clin Exp Pediatr. 2005;48(8):907-910.   Published online August 15, 2005
Intussusception and Meckel's diverticulum are very rare disorders in intrauterine or neonatal periods, which are causes of intestinal obstruction. We experienced a case of intussusception due to Meckel's diverticulum which caused intestinal obstruction in the neonate who had bilious vomiting a few hours after birth. We report this case with a brief review of the literature.
Original Article
Renal Anomalies in Neonates with Isolated Preauricular Tags
Myung Eun Hong, Seung Taek Yoo, Eun Jung Choi, Chang Woo Lee, Seung Taek Park, Yeon Kyun Oh
Clin Exp Pediatr. 2004;47(5):532-534.   Published online May 15, 2004
Purpose : The aim of this study was to determine the role of renal ultrasonography in neonates with isolated preauricular tags. Methods : We performed a retrospective study of 10,997 newborn infants delivered from January 1995 to June 2003 in Wonkwang University Hospital. Nineteen newborns born with isolated preauricular tags were assessed for renal anomalies by performing renal ultrasonography within one...
Incidence and Risk Factors of Rehospitalization with Respiratory Syncytial Virus Infection in Premature Infants
Eun Ah Lee, Jea Heon Jeong, Seung Taek Yu, Chang Woo Lee, Hyang Suk Yoon, Do Sim Park, Yeon Kyun Oh
Clin Exp Pediatr. 2004;47(5):510-514.   Published online May 15, 2004
Purpose : We performed this study to evaluate the risk of rehospitalization for respiratory syncytial virus(RSV) infection among premature infants discharged from a neonatal intensive care unit(NICU). Methods : We performed a retrospective study for rehospitalization for RSV infection and risk factors among premature infants who were admitted to NICU and discharged between May 2001 and April 2003 in Wonkwang...
Effect of Vitamin E on Cerebral Hypoxia-Ischemia in Neonatal Rats
Jung Eun Seok, Yeon Kyun Oh, Seung Taek Park
Clin Exp Pediatr. 2001;44(7):764-772.   Published online July 15, 2001
Purpose : In order to evaluate the hypoxia-ischemia induced neurotoxic effect and the protective effect of vitamin E as an antioxidant, cell number and cell viability were measured in cerebral neurons and astrocytes derived in neonatal rats. Methods : 7-day old neonatal rats were subjected to unilateral common carotid artery occlusion, and exposed to hypoxic condition for 3 hours. The protective...
Changes of Serum Tumor Necrosis Factor-α and Interleukin-1β in the Sepsis of Neonates
Mi Yeon Lee, Yeon Kyun Oh, Ji Hyun Cho
Clin Exp Pediatr. 1995;38(10):1307-1314.   Published online October 15, 1995
Purpose : Cytokines have recently been identified as important endogenous mediators of the host immune response to bacterial infection. But little is clarify about serum levels of cytokines in neonatal sepsis. The aim of this study was to know the changes of the level of cytokines during neonatal sepsis, to compare the level of cytokines in gram negative and gram...
Ultrasonographic Diagnosis by Pyloric Volume Measurement in Congenital Hypertrophic Pyloric Stenosis
Soon Kil Lee, Jae Wha Oh, Yeon Kyun Oh, Chang Guhn Kim
Clin Exp Pediatr. 1994;37(11):1595-1599.   Published online November 15, 1994
Real-time ultrasonogram was performed in 31 Pt. With CHPS, who was admitted at the pediatric department of Wonkwang University hospital from January 1991 to June 1993. Those who had positive results of pyloric volume for diagnosis of CHPS and were confirmed by surgery. The results were at follows, 1) The average ultrasonographic measurements of pyloric muscle thickness, pyloric diameter, pyloric length were...
The Risk of Seizure Recurrence of Pediatric Epileptic Patients While Receiving Anticonvulsant Drugs Treatment
Dae Sung Hwang, Byung Hyun Kim, Kwang Soo Oh, Yeon Kyun Oh, Hyang Suk Yoon, Jong Duck Kim
Clin Exp Pediatr. 1993;36(9):1271-1278.   Published online September 15, 1993
To evaluate the risk and factors associated with seizure recurrence on children with epilepsy while receiving the adequate anticonvulsant treament, we studied 58 patients with newly diagnosed epilepsy who were followed prospectively for a median of 26 months (range 7 to 54). The results were as follows: 1) Forty-four of the 58 patients (75.9%)had recurrence...
The Relationship between Spontaneous Diuresis and Changes of Pulmonary Function in Infants with Respiratory Distress Syndrome
Byeong Hyun Kim, Jae Kag Choi, Yeon Kyun Oh, Kwang Soo Oh, Hyang Suk Yoon, Chong Cuk Kim
Clin Exp Pediatr. 1993;36(8):1094-1100.   Published online August 15, 1993
To evaluate the relationship between spontaneous diuresis and improvement of pulmonary function in respiratory distress syndrome, 15 premature neonates requiring mechanical ventilation for RDS, who admitted in NICU of Wonkwang University Hospital from January 1990 to June 1992, were studied. The results were as follows(results are mean¡¾SEM) 1) Mean birth weight of study infants was 1.82¡¾0.08Kg, and mean gestational age was 32.80¡¾0.54...
Clinical analysis on newborn infants treated with mechanical ventilation.
Yeon Sim Kim, Dae Ho Choi, Cheol Woo Park, Yeon Kyun Oh
Clin Exp Pediatr. 1991;34(10):1346-1355.   Published online October 31, 1991
Clinical analysis of 48 neonates who treated with Mechanical ventilation in NICU at Won-Kwang University Hospital from February 1987 to July 1990 was performed. The results were as follows; 1) According to diagnostic categories, hyaline membrane disease was the most common in 26 cases (54.2%), and then postasphyxia syndrome 10cases (20.8%), apnea of prematurity 3cases (6.2%), sepsis 3 cases (6.2%),in their order. 2) 29 cases (60.4%) were bom...
Transcutaneous Oxygen and Carbon Dioxide Monitoring in Critically Ill Neonates.
Du Young Choi, Yong Kweon Kim, Yeon Kyun Oh
Clin Exp Pediatr. 1990;33(9):1202-1208.   Published online September 30, 1990
We studied the correlation of 85 paired arterial, transcutaneous P02 and 50 paired arterial, trans- cutaneous PCO2, which were obtained from 9 sick preterm infants within first week of their life, who were bom at the Wonkwang University Hospital from March. 1, 1988 to Feb. 28, 1989. And we also analysed the affect of the pH, body temperature, hematocrit and birth weight to...
A Clinical Observation of Neonatal Hyperbilirubinemia due to ABO Incompatibility.
Mi Jung Koh, Young Kyun Lee, Jin Hong Park, Yeon Kyun OH
Clin Exp Pediatr. 1990;33(9):1194-1201.   Published online September 30, 1990
A clinical and statistical study was performed on 43 neonates of hyperbilirubinemia due to ABO incompatibility who were admitted to department of pediatrics of Won-kwang University hospital from May 1987 to June 1988. The following results were obtained: 1) The incidence of hyperbilirubinemia within 48 hrs were 30.3% in the incompatible group and 10. 2% in the compatible group. So, hyperbilirubinemia was appeared earlier in...
A Case of Wilson-Mikity Syndrome.
Jung Suk Lee, Young Kyun Lee, Hyang Suk Yoon, Yeon Kyun Oh
Clin Exp Pediatr. 1990;33(5):675-679.   Published online May 31, 1990
Wilson-Mikity syndrome is a chronic lung disease in the premature infant characterized by respira- tory symptoms and became increasingly severe, and was associated with distinctive chest radiologic changes. We experienced a case of Wilson-Mikity syndrome in a premature infant. A brief review of related literature was made.
A Case of Potter Syndrome Type Ⅰ.
Jin Hong Park, Mi Jeong Koh, Yeon Kyun Oh, Chan Choi
Clin Exp Pediatr. 1989;32(8):1150-1154.   Published online August 31, 1989
We experienced a case of Potter syndrome type I characterized by polycystic kidney, pulmomnary hypoplasia and abnormal face in a 1 day-old male neonate with respiratory distress. Diagnosis was made with autopsy findings. A brief review of literature was made.
A Clinical Study of Meconium Stained Baby and Culture of the Tracheal and Gastric Meconium.
Dong Ryong Lee, Sung Ho Bae, Yeon Kyun Oh, San Ho Kim
Clin Exp Pediatr. 1988;31(12):1580-1587.   Published online December 31, 1988
Among the total of 3,102 newborns delivered at Won Kwang University Hospital from September 1984 to December 1986, a clinical study was performed of meconium stained baby and culture of the tracheal and gastric meconium. The results were as follows: 1) The incidence of meconium staining was 8.8% (272 cases) and the positive rate of meconium culture was 22.8% (62 cases). 2) The cultures of tracheal and gastric...
Case Report
A Case of Hereditary Spherocytosis.
Yeon Kyun Oh, Byeong Ho Lee, Young Ha Kim, Moon Ki Cho
Clin Exp Pediatr. 1986;29(9):1021-1027.   Published online September 30, 1986
We experienced a case of hereditary spherocytosis in a 6 year 3 month old boy who complained of anemia and jaundice. The diagnosis was confirmed by spherocytes in peripheral blood, osmotic fragility test, autohemolysis test and bone marrow smear. This patient had a splenectomy and was discharged in good health. To date no complic ation has been detected. A brief review...
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