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Typhlitis is a rare necrotizing colitis in which inflammation is confined to cecum. It occurs during
chemotherapy for malignancies, in terminal stage of aplastic anemia, in transplant patients. The
pathogenesis of typhlitis has included leukemic infiltration of the bowel, thrombocytopenia, direct
toxic effects of chemotherapy, steroid, bacterial invasion of the bowel wall secondary to neutropenia
and alteration of the bowel flora by broad-spectrum antibiotics.... |