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The Korean pediatric association is conducting the analysis of disease patterns of children by the body organ system. For the purpose of assessing the disease patterns in patients of the pediatric age in Korea, we performed a statistical analysis of diseases of patients admitted to the department of pediatrics in 36 hospitals having pediatric residency programs in 1987. The results obtained were as follows, 1) Total... |
The utilization of pediatric emergency services has increased rapidly in recent years with general recognition of its funtion. The authors reviewed 11,089 patients visiting emergency room of Seoul National University Children’s Hospital during last two years from Jan. 1st 1986 to Dec. 31st 1987. The findings obtained were as follows: 1) There were 5,110 visits in 1986 and 5,979 visits in 1987. First visit was... |
A clinical study was made on 103 cases of Mycoplasma pneumoniae pneumonia patients during the period of 3 years from July ’84 to June '87. Indirect hemagglutination test (IHA) and/or cold agglutinin test (CAT) were measured and follow-up studies were done until the 50th day of the illness. Each titer was compared for analysis of interrelationship between them. And we obtained following results: 1) The highest... |
We reviewed 22 newborn patients with palpable abdominal mass among 9, 834 newborn infants admitted to nursery and NICU of Seoul Natinal University Children’s Hospital from Jan. 1, 1983 to Dec. 31, 1987. The results were summarized as follows: 1) The incidence was 2.2/1,000 admission. The difference of incidence was not significant between preterm infants and term infants. 2) The most common etiology of neonatal abdominal masses is... |
This study was undertaken to evaluate the Natueral-Killer (NK) cell and Lymphokine-Activated-Killer (LAK) cell activity of cancer patients for the prupose of understanding of spontaneous cell-mediated cytotoxicity (SCMC) in cancer patients and understanding of interrelationship between NK cell and LAK cell. Total 9 cases of malignant tumor (7 cases: Acute leukemia, 2 cases: malignant lymphoma) below 15 years of age, who were on remission... |
This study was desinged to assess the accuracy of the ratio of pulmonary to systemic blood flow (Qp/Qs) measured by non-invasive continuous wave (CW) Doppler echocardiography comparing with other non-invasive Radionu- clide Angiocardiography (RNA) and invasive Fick method. Seventeen children with congenital heart disease, aged 14 months to 15 years, admitted for cardiac opention to this hospital, were studied. High correlations were found between the... |
This study determines the accuracy of Doppler echocardiography for predicting the presence of pulmonary artery hypertension from Doppler pulmonary artery velocity traces. The patient group included 26 patients with congenital cardiac disease who had undergone catheterization. Doppler measurements of acceleration time(AT), right ventricular ejection time (RVET), and AT/ RVET were compared with pulmonary artery pressure (PAP) and mean pulmonary artery pressure (m-PAP). We devided the patients in... |
Ventricular tachycardia (VT) is uncommon, but is in increasing tendency probably due to better case detection and longer survival of the patients with complex congenital heart disease. Widespread use of 24 hour ECG has contributed a lot to better understanding of ventricular tachycardia. Fourteen cases of ventricular tachycardia diagnosed by 24 hour ECG at Seoul National Children’ s Hospital from Feb. 1986 to Sep.... |
Acute poststreptococcal glomerulonephritis is generally stated to be the most common cause of acute nephritis in childhood and secondary to an immunologic mechanism. In acute poststreptococcal glomerulonephritis, there have been several reports on the change of serum complement levels in the course of disease. This paper reports on observation of change of serum C3 & C4 levels and its clinical significance in 41 cases of... |
Among 223 cases who were admitted to the Department of Pediatrics, Hanyang University Hospital from January 1980 to December 1987 under the diagnosis of Urinary Tract Infection(UTI), 132 cases of E. coli UTI were compared with 91 cases of non-E. coli UTI by age, sex distribution, clinical manifestation, laboratory results and clinical course. The results obtained were as follows: 1. There were no significant differences of... |
A 2 year 5 month old female infant with late infantile metachromatic leukodystrophy was diagnosed by typical clinical and laboratory findings and Arylsulfatase A assay in 24h urine. The patient’s mother was confirmed as a heterozygote by Arylsulfatase A activities in 24h urine which was about one half of normal control groups. |
Methylmalonic acidemia is an inborn error of metabolism, which is characterized by excretion of large amount of methylmalonate, and is transmitted as an autosomal recessive traits. The clinical symptoms begin in early life and are recurrent vomiting, lethargy, dehydration, failure to thrive. Laboratory findings show ketosis, metabolic acidosis, methymalonic aciduria with normal serum cobalamin level, hyperammonemia, pancytopenia. Two treatment regi- mens exist and should... |
This is a report of our experience of Peutz-Jeghers syndrome in a 14 year old girl having family history. She was admitted with complaints of crampy abdominal pain and vomiting, and showed melanotic pigmentation on the lips, face around nose, oral mucosa around molar areas, fingers and toes. Colon study revealed multiple polyposis in colon and small bowel. In family, her father has melanotic... |
Cytophagic histiocytic panniculitis is a chronic, benign, visceral and cutaneous histiocytic (cyto- phagic) paniculitis, progressing to liver dysfunction, jaundice and a terminal hemorrhagic diathesis. We have experienced a case of cytophagic histiocytic panniculitis in an 11 year old male who had developed recurrent fever and subcutaneous nooules since infancy, progressing to liver dysfunction, jaundice and hemorrhagic diathesis. The noaular biopsy also showed a characteristic... |
The characteristic features of late hemorrhagic disease of infancy are noraml pregnancy and delivery, no vitamin K prophylaxis at birth, often breast feeding, normal development and good health until the acute bleeding with a high incidence of intracranial hemorrhage. We have experienced 2 cases of intracranial hemorrhage, 1 case of bleeding from injection site due to vitamin K deficiency. |
Holotelencephaly is a congenital malformation of the telencephalon which is characterized by developmental failure of the cerebral hemispheres and frequently associated with midline facial defect. We experienced a case of holotelencephaly, alobar type, associated with microphthalmia and choanal atresia. Diagnosis was confirmed by autopsy. A brief review of literature was made. |
Hypokalemic familial periodic paralysis is a type of periodic paralysis characterized by recurrent attack of weakness and paralysis of limb muscles with hypokalemia. The disease is inherited by autosomal dominant trait in case of familial type. We have experienced a case of periodic paralysis in a 10-years old boy whose father had died due to periodic paralysis. The diagnosis was easily established by history,... |
A clinical study was performed on 23 patients of Sydeham’s chorea in the children who admitted to the pediatric department of SNUH from Jan. 1980 to Dec. 1987. The results were as follows: 1) Among 316 patients with rheumatic fever, 10 patients (3%) had a chorea. 2) The age at onset of chorea ranged from 8 to 16 years. 3) The ratio of female to male was 1.9... |
The syndrome of Mixed Gonadal Dysgenesis is characterized by a unilateral testis, usually intra- abdominal a streak gonad on contralateral side, persistent Mullerian structures and ambiguous genitalia. These patients are chromatin negative and exhibit XO/XY mosaicism, probably resulting from a cytogenetic error very early in embryogenesis. The testis and the streak gonad should be removed because of the potential devlopement of a gonadoblastoma and the virilization... |