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Volume 33(8); Aug 1990
Original Articles
Seventeen Years Experience on Inborn Errors of Metabolism A Study for Future Development of Inborn Errors of Metabolism in Korea.
Hong Jin Lee, Hyung Ro Moon
J Korean Pediatr Soc. 1990;33(8):1031-1036.   Published online August 31, 1990
In Korea, the study of inborn errors of metabolism is very primitive. Even the incidence and prevalence of the disease of inborn errors of metabolism are not known in Korea. We have done this study of inborn errors of metabolism in Korea and concluded that: 1) The varieties and incidences of inborn errors of metabolism in Korea might be relatively diverse and high. 2) Nation wide mandatory...
Statistical Observation on Neonate.
Hong Ja Kang, Nam Hyuk Joo, Soon Ok Byun, Ji Sub Oh
J Korean Pediatr Soc. 1990;33(8):1037-1047.   Published online August 31, 1990
Statistical observation was performed on 11,857 cases of neonates which were seen in the nursery, Pusan, Wallace Memorial Baptist Hospital, during the past 5 years from Jul. 1983 to Jun. 1988. The results were as follows: 1) Among 11,857 neonates, the percentage distribution by birth weight was 6.1% for 2,500 gm or less, 3.7% for 4,001 gm or more and the sex ratio of male...
The Apgar Score and Umbilical Arterial pH in the Newborn.
Hoo Jae Hann, Eun Ae Park, Kyung Hee Kim
J Korean Pediatr Soc. 1990;33(8):1048-1056.   Published online August 31, 1990
In this prospective study, the relation between the Apgar scores and umbilical arterial pH at birth was assessed. 314 newborns of gestational age 24 to 42 weeks were included in this study； (95 were preterm and 219 were full-term) The l and 5-minute Apgar scores were directly related to gestational age. In preterm babies, the Apgar scores tend to be low in spite...
Total Protein, Albumin and IgG Analysis of Serum and Cerebrospinal Fluid in Control and Aseptic Meningitis.
Nak Won Choi, Myung Ja Yoon, Hae Rung Chung, Dong Hyuk Kum
J Korean Pediatr Soc. 1990;33(8):1057-1064.   Published online August 31, 1990
Determination of proteins in CSF and serum demonstrates two pathological conditions of CNS, namely a blood brain barrier (B.B.B.) damage and a selective elevation of IgG due to synthesis within CSF CNS. -Q albumin ratio is a sensitiv eand adequate parameter for demonstration of B.B.B. Serum CSF . „ / s^IgGratl0\ I pep \ damage and IgG Index = I Serum ) albumin ratio is a better measurement for local production of IgG...
Clinical Investigation of Chlamydia Pneumonia in Infants.
Jong Hoon Park, Se Geon Park, Kwang Chul Lee, Young Sook Hong, Young Chang vTockgo
J Korean Pediatr Soc. 1990;33(8):1065-1073.   Published online August 31, 1990
We performed chlamydia antigen test by enzyme immunoassay in 322 infants who were admitted because of pneumonia. Clinical investigation and statistical analysis were done between chlamydia antigen positive group and negative group. The results obtain were as follows 1) Chlamydia antigen positive were resulted in 42 cases (13.04%) among 322 cases. 2) The mean age of Chlamydia positive and negative group were 14.2±6.2 weeks and 11.5±5. 7weeks respectively. 3) Afebrile...
Assessment of Cardiac Output by Doppler Ultrasound Technique Alone.
Young Ho Ahn, Sung Min Choi, Nam Geun Heo, Sang Bum Lee
J Korean Pediatr Soc. 1990;33(8):1074-1080.   Published online August 31, 1990
The normal range of ascending aortic blood velocity was determined in 23 healthy children including 8 newborn infants and compared with 12 anemic children, using a pulsed Doppler ultrasound technique from suprasternal long axis view. Integration of the area under the velocity-time curve for each heart beat gave stroke distance, which, when multiplied by heart rate, gave minute distance. Stroke distance and minute distance are...
Studies on the Change of Pulmonary Artery Pressure in Early Neonatal Period.
Jung Ae Kim, Yung Kyun Oh, Byung Kiu Park, Hee Shang Youn, Myung Kul Yum
J Korean Pediatr Soc. 1990;33(8):1081-1086.   Published online August 31, 1990
The change of postnatal pulmonary artery pressure was studied with doppler echocardiography and phonocardiogram in 40 normal full term neonates before 6 hours, between 6 〜 24 hours, 24~48 hours, 48-72 hours, 72 hours 〜 7 days. The results of study were as follows: Pc-To interval (sec) decreased (0. 071 ±0.002, 0.062±0.003, 0.050±0.002, 0.037±0.007, 0.027±0.003) and AT/ET ratio increased (0. 24±0.01, 0.30±0.02, 0.40±0.03, 0.40±0.04,...
Prevalence Study of Anemia among Urban and Rural Middle School Girl Students.
Jeong Ok Hah, Mi Hwa Kang, Jeung Ho Kim
J Korean Pediatr Soc. 1990;33(8):1087-1096.   Published online August 31, 1990
This study was conducted to investigate the prevalence rate of anemia and iron deficiency in pubertal girls in urban and rural areas. Venous peripheral blood was sampled from 346 girls who were randomly selected from 1,900 students of one girls’ middle school in Taegu city and all of 311 girls attending two middle schools in rural area, one in Cheungdo county and, another...
A Clinical Study on the Posterior Subcapsular Cataracts in Childhood Nephrotic Syndrome.
Dong Kyu Jin, Ja Wook Koo, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jong Hoon Lee, Young Suk Yu
J Korean Pediatr Soc. 1990;33(8):1097-1103.   Published online August 31, 1990
A clinical study was carried out in 73 children with nephrotic syndrome who had had regular ophthalmologic examination annually at Seoul National University Children’s Hospital from March 1976 to February 1990 with the aim of finding the relationship between the posterior subcapsular cataract (PSC) and the effect of corticosteroids. The results were summarized as follows: 1) The number of patients with PSC were 23 cases...
The Pharmacokinetics, Acute Biological Effects and Safety of Recombinant Human Growth Hormones.
Jong Jin Seo
J Korean Pediatr Soc. 1990;33(8):1104-1110.   Published online August 31, 1990
The pharmacokinetics, acute biological성fccts and safety of yeast-derived recombinant methionyl- hGH (LBD-003), the first biosynthetic hGH in Korea, were studied in 10 healthy young adults who were administered 8 IU/day intramuscularly for four consecutive days. 1) GH levels reached a mean (±SD) peak of 27.5±10.7 ng/ml at 3.4±0.8 hours following the first dose, and other pharmacokinetic parameters of LBD-003 were similar to those reported for pituitary...
A Case of Recessive Epidermolysis Bullosa Dystrophica.
Young Tae Kim, Hak Won Kim, Seung Hee Oh, Soo Jee Moon, Chan Kum Park
J Korean Pediatr Soc. 1990;33(8):1111-1116.   Published online August 31, 1990
Epidermolysis Bullosa Dystrophica (EBD), a subtype of epidermolysis bullosa, is a rare inherited disease characterized by induction of blisters and erosions in skin and mucous membrane by minor or no trauma, which heal with scar formation. Clinical course is more severe in recessive type of EBD than dominant type. We have experienced a case of recessive EBD in a one day old female patient...
A Case of Partial Trisomy 5q.
Hye Sun Choi, Gyu Young Jung, Eui Soo Park, Jin Sam Ro, Yong Gyun Back, Myung Su Yoo, Yul Hee Cho, Chun Kun Lee
J Korean Pediatr Soc. 1990;33(8):1117-1122.   Published online August 31, 1990
Until now, about 19cases of partial trisomy 5q were reported. The authors experienced a patient of partial trisomy 5q who admitted due to bronchiolitis and had prominent forehead, microcephaly, ptosis, dysmorphic ear, cryptorchism, flat foot, psychomotor retardation, convulsion and so on, Brain CT scan showed brain 는trophy. Chromosome study showed 46, XY, dup (5q)(13-23) As this is the first case in Korea, it is worthwhile...
A Case of Acute Interstitial Nephritis Associated with Yersinia Pseudotuberculosis Infection.
Keun Hee Chung, Yoo Mee Kim, Mee Won Kim, Soon Gi Kim, Moon Soo Park, Jin Keun Chang
J Korean Pediatr Soc. 1990;33(8):1123-1128.   Published online August 31, 1990
Authors recently experienced a case of acute interstitial nephritis associated with Yersinia pseudotuberculosis infection in 10-8/12 year old boy, who was admitted to prolonged high fever. On 3rd hospital day, puffy face and oliguria were noted. BUN and serum creatinine rose to peak level, 94.1 mg/dl and 10.1 mg/dl, respectively on 7th hospital day. After then renal functions were normal- ized gradually without specific...
A Case of Subdural Empyema Complicating Hemophilus Influenzae Meningitis.
Myung Sun Oh, Nan Kyung Kim, Sae Yoo Jung, Soon Ung Kang, Jung Kyou Kim, Byong Kwan Son
J Korean Pediatr Soc. 1990;33(8):1129-1133.   Published online August 31, 1990
We have experienced Hemophilus influenzae meningitis complicated by subdural empyema, which was confirmed by computerized tomography and subdural tapping. The patient was 5-month-old female who was admitted with high fever and generalized siezure. Hemophilus influenzae meningitis was confirmed by the culture of spinal fluid. The organism was sensitive to the ampicillin but the clinical course was not satisfactory with persisting high fever because of complication....
A Case of Esophageal Duplication.
Hyung Kuk Ham, Jeong Kyu Seoh, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim, Hee Jae Joo
J Korean Pediatr Soc. 1990;33(8):1134-1139.   Published online August 31, 1990
Esophageal duplication, a term used synonymously with enteric cyst, foregut cyst, gastroenteric cyst, enteric duplication, and etc, is a rare developmental anomaly which occures during differentia- tion of the larynx, trachea, and bronchi from the primitive foregut. They may cause dysphagia, regurgitation, pneumonia, hemoptysis, and occasionally produce alarming airway obstruction. We experienced a case with chief complaints of pale appearance and swallowing difficulty in...
A Case of Hemolytic Uremic Syndrome.
Seung Cheol Lee, Chong Guk Lee, Seong Hwan Kim, Sang Woo Kim, Hyun Soon Lee
J Korean Pediatr Soc. 1990;33(8):1140-1147.   Published online August 31, 1990
A female child aged 7 months was admitted because of high fever, vomiting and stuporous conciousness and revealed to have hemolytic uremic syndrome. Anuria persisted 13 days and required peritoneal dialysis 4 times a day during the anuric period. Her kidney function recovered somewhat after dialysis but neurologic complications of marked hydrocephalus and brain atrophy remained.
Three cases of Lyphodystophia Centrifugalis Abdominalis Juvenilis.
Young Soo Chun, Byung Hee Kim, Young Youn Choi, Tai Ju Hwang
J Korean Pediatr Soc. 1990;33(8):1148-1154.   Published online August 31, 1990
The Lipodystropia centrifugalis abdominalis juvenilis (LCAJ) is a skin disorder characterized by progressive, centrifugal loss of subcutaneous fat on inguinal and/or axillary region. The lesion has slightly red border and scaly change on it. But other skin manifestations or other organ involvements are not the feature of the disease. We have experienced 3 cases of LCAJ. They were 7 years 1 month old body,...
Two Cases of Cerebral Gigantism (Sotos Syndrome).
Hee Jeung Ahn, Young Tae Kim, In Hoon Seol, Jeh Hoon Shin
J Korean Pediatr Soc. 1990;33(8):1155-1158.   Published online August 31, 1990
Cerebral gigantism, the condition described by Sotos et al in 1964, consists of excessively rapid growth rating from infancy followed by a normal growth rate, acromegalic features, and a non- progressive neurological disorder manifested by clumsiness. The etiology of cerebral gigantism is not clear. Increased growth hormone levels have not been documented and somatomedin activity was found to be within normal range as yet...
A Case of Adrenal Cortical Carcinoma.
Ho Won Kang, Hong Ja Kang, Hong Bae Kim, Ji Sub Oh
J Korean Pediatr Soc. 1990;33(8):1159-1165.   Published online August 31, 1990
This is a case report of adrenal cortical carcinoma in a 2 year 7 month old male patient who was diagnosed by clinical features, endocrinologic studies, radiologic studies and pathologic examina- tions. Cushing syndrome and virilization caused by adrenal cortical carcinoma were found. Left total adrenalectomy was performed. No evidence of metastasis was found at the time of operation. 3 months later, lung metastases...
The Right of Ingeritance and Family Name of Embryo by Artificial Conception (52).
Gook Jin Moon
J Korean Pediatr Soc. 1990;33(8):1166-1167.   Published online August 31, 1990
Medical Common Sense
A Criteria for Calculation of Hospital Rate for the Health Insurance (52).
Chong Kil Lee
J Korean Pediatr Soc. 1990;33(8):1168-1169.   Published online August 31, 1990
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