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Volume 34(2); Feb 1991
Original Articles
The Future Problems in Kawasaki Disease.
Du Bong Lee
J Korean Pediatr Soc. 1991;34(2):151-163.   Published online February 28, 1991
Molecular analysis of childhood acute lekemia.
Hack Ki Kim, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
J Korean Pediatr Soc. 1991;34(2):164-171.   Published online February 28, 1991
Immunoglobulin (Ig) and T cell receptor 0 chain (TcR分) gene rearrangements can be used as ”genetic marker” of lineage and clonality in the study of lymphoproliferative disease. We analyzed genomic DNA of the bone marrow mononuclear cells from twenty six patients with acute leukemia in children. The patients were seventeen cases of acute lymphocytic leukmia (ALL), seven cases of acute nonlymphocytic leukemia (ANL) and...
Treatment of severe aplastic anemia: comparison between bone marrow transplantation and immunomodulation.
Dae Chul Jeong, Sung Dong Choi, Woo Gun Choi, Hack Ki Kim, Kyong Su Lee, Du Bong Lee
J Korean Pediatr Soc. 1991;34(2):172-179.   Published online February 28, 1991
Twenty, six children younger than 15 years with severe aplastic anemia underwent either bone marrow transplantation or immunomodulation therapy (antilymphocyte globulin with cyclosporin A therapy). Six patients who had an HLA-identical sibling donor underwent bone marrow transplantation after conditioning with cyclophosphamide, procarbazine and antilymphocyte globulin. Twenty children who did not have an HLA-identical donor recieved antilymphocyte globulin and cyclosporin A. The results were as follows; 1) Hematologic responses:...
A clinical study on influences of premature rupture of membranes in the newborn infant.
Ji Sun Cho, Young Sun Ko, Soon Ok Byun, Ji Sub Oh
J Korean Pediatr Soc. 1991;34(2):180-189.   Published online February 28, 1991
A clinical study was made on 607 newborns of mothers with premature rupture of membrane (PROM group) and 5,775 newborns of mothers without ruptured membrane Baptist Hospital from January 1987 to December 1989. The results are summarized as follows: 1) The overall incidence of PROM was 9.5% with little yearly variations. 2) 11.9% of all babies with PROM were bom prematurely, significantly higher than the incidence of control...
Transplacental transmission of hepatitis B virus from carrier nothers to neonates.
Soh Yeon Kim, Chul Lee, Dong Gwan Han
J Korean Pediatr Soc. 1991;34(2):190-196.   Published online February 28, 1991
Neonates bom to hepatitis B carrier mothers at Yongdong Severance Hospital, Yonsei University College of Medicine were sampled for hepatitis B viral markers using venous blood drawn from external jugular vein within 3 hours after birth and the following results were obtained. Two thousand nine hundred and seventy two pregnant women who received prenatal care at Yongdong Severance Hospital, Yonsei University College of Medicine...
Acute pyogenic arthritis of hip in neonate and infant.
Mi Jung Kim, Young Ah Lee, Young Pyo Chang, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun, Hak Jin Min, In Ho Choi
J Korean Pediatr Soc. 1991;34(2):197-205.   Published online February 28, 1991
Acute pyogenic arthritis of hip is a serious infection that can lead to truly devastating complica- tions especially in neonatal period and infancy. Clinical survey on twelve neonates and infants (14 hip joints) with acute pyogenic arthritis of hip who were admitted to the Departments of Pediatrics and Orthopedic Surgery, Seoul National University Hospital from Jan. 1980 to Dec. 1989 were done. The results...
Clinical studies of meningitis cases in children.
Chun Oh Lee, Song Nyeon Choi, Yong Wook Kim, Ki Bok Kim
J Korean Pediatr Soc. 1991;34(2):206-216.   Published online February 28, 1991
A clinical studies were carried out on 442 cases who were admitted to the Department of Pediatrics, Kwangju Christian Hospital under impression of meningitis during a 7 year period form January, 1982 to December, 1989. The results are summerized; 1) No yearly fluctuation in incidence for both purulent and aseptic meningitis was noted, but decreasing tendency was clearly seen for tuberculous meningitis. 2) Purulent meningitis affected mostly babies...
Upper gastrointestinal diseases diagnosed by upper gastrointestinal fiberoptic endoscopy in children.
Jong Moon Hwang, Pal Dong Kim, Tae Won Paik, Chin Moo Kang
J Korean Pediatr Soc. 1991;34(2):217-222.   Published online February 28, 1991
A clinical analysis was carried out on 83 cases of upper gastrointestinal diseases, diagnosed by fiberoptic endoscopic examination in children, who had visited the department of pediatrics, Keimyung University, Dong San Hospital from January 1980 to June 1987. Following results were obtained: Out of 83 cases, 61 (73.5%) were between 11-15 years of age and the male to female ratio was 3. 6:1. The disease distribution...
Prevalence of asymptomatic hematuria, proteinemia and glucosuria in primary school children in Chonju area.
Jin Oh Kim, Joseph Choi, Soo Cheol Cho, Dae Yeol Lee, Jung Soo Kim
J Korean Pediatr Soc. 1991;34(2):223-229.   Published online February 28, 1991
The present study was performed to define the prevalene of asymptomatic hematuria, proteinuria,and glucosuria. A total of 5011 primary school children in Chonju city were examined with test strip urinalysis during the period of one month from June to July 1989. Test strip (Hema-Combistix) was used in this examination. The results were as. follows: 1) Prevalence of hematuria, proteinuria and glucosuria were 0.8% (40 children), 0.78%...
A clinical study on neonatal seizures.
Bong Sik Kong, Ri Sa Lee, Sang Kyu Park, Ho Jin Park
J Korean Pediatr Soc. 1991;34(2):230-239.   Published online February 28, 1991
Clinical observation were made on 57 cases of neonatal seizure who were admitted to the Depart- ment of pediatrics, Seoul Red Cross Hospital during the period of 7 years from Jan. 1983 to Dec. 1989. The results were as follows: 1) According to the type of delivery of neonates which showed neonatal seizure, normal vaginal delivery were 41 cases (71.9%), C-section delivary 11 cases (19.3%)...
The clinical study on MCLS.
Young Sun Ko, Ji Sun Cho, Hong Bae Kim, Ji Sub Oh
J Korean Pediatr Soc. 1991;34(2):240-249.   Published online February 28, 1991
Forty six children with mucocutaneous lymph node syndrome were diagnosed and treated through admission at the Department of Pediatrics, Wallace Memorial Baptist Hospital from January 1987 to January 1990. Ther were investigated for clinical pattern and laboratory correlations. The results were as follows: 1) Most patients (95.7%) were under four years of the age. 2) The ratio of male to female was 1.6:1. 3) Seasonal incidence was high in...
Two cases of Edward syndrome.
Jin Bok Hwang, Woo Hyun Kwon, Soon Young Song, Chang Ho Han, Hye Li Chung, Young Dae Kwon
J Korean Pediatr Soc. 1991;34(2):250-255.   Published online February 28, 1991
We presented two cases of Edward syndrome in this report. Both cases were bom with multiple congenital malformation which were characterized by low set malformed ears, micrognathia, webbed neck, rocker bottom feet, small pelvic and abducted, index and third fingers flexed upon with simian crease and small sized great toes with mild dorsifiexion. A large VSD was found on autopsy in one case who...
Two cases of meconium peritonitis.
Hye Kyung Nam, Dong Hwan Lee, Sang Jhoo Lee
J Korean Pediatr Soc. 1991;34(2):256-260.   Published online February 28, 1991
Meconium peritonitis is a non-bacterial foreign body and chemical peritonitis occurring during intrauterine or early neonatal life as the result of an abnormal communicatiion between the bowel contents and the peritonesal cavity. We experienced two cases of meconium peritonitis, diagnosed in according to the clinical and radiologic features, in two female neonates who had the chief complaint of vomiting and abdominal distention. A brief review...
A case of Caroli's disease.
Seong Hee Jung, Cheol Ho Chang, Han Tchah, Jeong Kee Seo, Kwi Won Park, In One Kim, Kyung Mo Yeon, Je Geun Chi
J Korean Pediatr Soc. 1991;34(2):261-266.   Published online February 28, 1991
Caroli’s disease was first described by Caroli in 1958 and characterized by segmental cystic dilatation of the intrahepatic bile ducts. There is stasis of bile with stone formation in the dilatated ducts, giving rise to frequent attacks of pain and cholangitis. In the past, diagnosis of the Caroli’s disease is rarely established prior to operation and subsequent cholangiography. Recently, with ultrasonography, computerized tomography, radioisotope...
Three Cases of Pathologic Aerophagia.
Y.A. Lee, M.R. Kim, Y.H. Choi, E.J. Bae, H. Cha, J.K. Seo, H.R. Moon
J Korean Pediatr Soc. 1991;34(2):267-272.   Published online February 28, 1991
The pathologic aerophagia in childhood is a clinical entity simulating various gastrointestinal disorders in its manifestation. The correct diagnosis is indispensable to the management of the patients. The diagnostic clue of pathologic aerophagia in childhood could be obtainable from the detailed family history pertaining situational status in sibship and interaction within the family and the pathologic aerophagia should be regarded as a type of...
Two cases of islet cell hyperplasia with nesidioblastosis.
Myeong Ku Cho, Kyeong Bae Park, Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee, D.H Lee
J Korean Pediatr Soc. 1991;34(2):273-280.   Published online February 28, 1991
Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose...
A case of hypomelanosis of Ito accompanying ureteral duplication and hypomelanotic scalp hair.
Dong Woo Son, Beom Soo Park, Heon Seok Han, Hae Il Jung, Yong Choi, Hyung Ro Moon, Seon Hoon Kim, Hwang Choi
J Korean Pediatr Soc. 1991;34(2):281-286.   Published online February 28, 1991
Hypomelanosis of Ito (incontinentia pigmenti achromians) is a cutaneous abnormality consisting of bizarre, whorly, linear, or patchy hypopigmentation over variable portion of body surface. Multiple assocaited defects in other systems occur in three quarters of the affected individuals. Most common- ly, the central nervous system, eye, and musculoskeletal structures are involved. It is suggested that the cutaneous abnormality, which is often detectable at birth...
A case of thrombasthenia.
Yong Bae Suh, Eun Kyoung Sohn, Yong Mook Choi, Chang Il Ahn
J Korean Pediatr Soc. 1991;34(2):287-291.   Published online February 28, 1991
Glanzmann’s thrombasthenia is a congenital disorder of platelet function with missing or abnormal platelet plasma membrane glycoprotein Ilb/IIIa which function as receptors for fibrinogen and other high-molecular-weight adhesive proteins which are important for platelet aggregation. We have experienced a case of thrombasthenia in a 12 month old male whose chief complaints were easy bruising and frequent epistaxis. The beeding time was prolonged in the...
A case of hyperimmunoglobulin E syndrome.
Myeong Cheol Shinn, Sung Dong Choi, Byung Gyu Suh, Jin Han Kang, Joon Sung Lee
J Korean Pediatr Soc. 1991;34(2):292-298.   Published online February 28, 1991
The hyperimmunoglobulin E syndrome is a primary immunodeficiency disorder characterized by serious recurrent bacterial infections of the skin and respiratory system in early life, and markedly elevated serum IgE level. These recurrent infections are generally subcutaneous abscesses caused by Staphylococcus aureus. Also, additional characteristrics of this syndrome include coarse facial appearance, chronic pruritic dermatitis and eosinophilia. The baisic immunologic defect mechanism in hyperimmunoglobulin E syndrome is...
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