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Volume 35(3); Mar 1992
Effect of Intralipid infusion on the Metabolism
Baek Keun Lim
J Korean Pediatr Soc. 1992;35(3):289-295.   Published online March 15, 1992
Original Articles
A comparison Study on Soluble FcεR II/CD23 and IL-4 Activities nin the Serum of Children with Allergic and Non-allergic Diseases
Ha-Baik Lee, Han Young Lee, Hahng Lee
J Korean Pediatr Soc. 1992;35(3):296-305.   Published online March 15, 1992
Allergy classically rfes to hypersensitivity reaction induced by chemical mediators released from mast cells and basophils activaed by binding allergens contained in house dust, animal dander, pollen, fungus, food and others to IgE (reaginic antibody) bound on these cells. The significance of low affinity Fc receptor for IgE ( FcεR II, CD23, FcεR II/CD23) on B and T lymphocyts, macrohage ,...
The Effec of Conditiond Media Cultued from the Thymocytes and the Splenocytes on the Regulation of Antibody Isotypes; In Vitro Immunization-III
Dong Soo Kim, Geun Woong Noh, Soon Hwan Oh
J Korean Pediatr Soc. 1992;35(3):306-314.   Published online March 15, 1992
We had developed a method of in-vitro immunization to increase antibody titer using several cnditioned media which were developed from mouse splenocyts and thymocytes. Using fetal calf serum, the splenocytes of the mouse were divided into two types; adherent cells and non-adherent cells. We used PHA to stimulate the adherent cells to produce PHA-stimulated adherent cell conditioned medium (ACSM-P). Non-adherent...
Clinical Study on Congenital Anomalies
Young Soo Kwon, Heung Keun Oh, Jin Jae Kim, Chang Ok Soh, Jin Hee Jung, Jin Young Jung
J Korean Pediatr Soc. 1992;35(3):315-321.   Published online March 15, 1992
Congenital malformations are known as a major cause of perinatal death. But the causes and Mechanisms of malformations ae still not understood in many cases. So, a clinical stduy was one about congenital malformaions on 8,584 deliveries a Haesung Hospital during the period of 5 and 7/12years from Jan. 1, 1985 to Jul. 31, 1990. The results were as follows: 1) The incidence...
Clinical Observation on Newborn using Artificial Ventilator
Hyun Seung Park, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn
J Korean Pediatr Soc. 1992;35(3):322-329.   Published online March 15, 1992
Retrospective clinical analysis of 5 and a half yeas experience with artificial ventilaion on 187 neonas in NICU of National Medical Center, from Jan. 1985 to Dec. 1990, was done. The results were as follows; 1) Number of patients, who required respiratory therapy with aritificial ventilation, was 187 and the percentage of these patients to all hospitalized neonates was 11.4%. 2) Number...
The Clinical Observation in Kawasaki Disease
Young Jin Jang, Joong Gon Kim, Yong Soo Yun
J Korean Pediatr Soc. 1992;35(3):330-341.   Published online March 15, 1992
The one-hundred thirty five cases with Kawasaki disease who wre diagnosed and treated at the department of pediatrics, Seoul National University Children뭩 Hospital from September 1984 to December 1990, were investigated for clinical pattrns and laboratory correlations. The results were as follows; 1) Most patients (86%) were under 4 years of the age. 2) boys wee more prevalent than girls, as a ratio...
Treatment of Kawasaki Disease with Single High-dose Intravenous Gammaglobulin
Mi Koo Kang, Eun Young Cho, Young Hwue Kim, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
J Korean Pediatr Soc. 1992;35(3):342-348.   Published online March 15, 1992
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children under 5 years of age. Coronary aneurysms are the most serious complications and 15-20% of patient develop coronary aneurysm. We studied 50 children who wre diagnosed as Kawasaki disease and treated simultaneously with single high-dose gammaglobulin (2 gm/kg/day) and aspirin at Asan Medical Canter...
The Pharmacokinetics and Biological Effects of Yeat Dervied Recombinant Methionyl Growth Hormone in growth Hormone Deficient Children
Byung Churl Lee
J Korean Pediatr Soc. 1992;35(3):349-354.   Published online March 15, 1992
The parmacokinetics and biological effects of an recombinant methionyl growth hormone(LBD-003) produced by the expression of genomic hGH in a yeast cell line, were studied in growth hormone deficient children. Twelve patients were randomly assigned to two age-matched subcutaneous and intramuscular groups. Each group consists of 6 patients. Each subject received an dosage of 0.1 U hGH(LBD-003)/kg, BW, Blood was drawn before...
Effucact of Adenosine Triphosphate in Infants and Children with Supraventricular Tachycardia
Yae Kyung Suh, Chung Il Noh
J Korean Pediatr Soc. 1992;35(3):355-363.   Published online March 15, 1992
Acute tachyarrhythmia in infancy and childhood may be life-threatening if it is not treated promptly and accurately. The selection of a safe and effective pharmacologic agent is work in hand. We tried ATP (adenosine triphosphate) to pediatric patients with acute epidsodes of supraventricular tachycardia for therapeutic or diagnostic purpose and determined the safety and effectiveness of the drug. ATP was given...
The Effect of Prostaglandin E1 Infusion for Palliation of Ductus Dependent Cyanotic Congenital Heart Disease in Neonates
Ji Hee Park, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
J Korean Pediatr Soc. 1992;35(3):364-370.   Published online March 15, 1992
Prostaglandin E1 (PGE1) was administered to 12 neonates with cyanotic congenital heart disease in whom pulmonary or systemic blood flow were entirely or significantly dependent on persistent patency of the ductus arteriosus. 10 neonates responded favorably to PGE1, by showing significant increase of PaO2 after PGE1 infusion but remaining 2 neonates with hypoplastic left heart syndrome failed to respond. The...
Ifosfamide in the Pediatric Malignant Solid Tumors
Sang Wook Choi
J Korean Pediatr Soc. 1992;35(3):371-380.   Published online March 15, 1992
Ifosfamide (IFO), one of a number of alkylating agents, has been given with Adriamycin (ADR) or Etopsoide (VP-16) to the thirteen malignant solid tumor patients (five neuroblastoma, six osteosarcoma, one rhabdomyosarcoma, one leigomyosarcoma). IFO 1.8g/m2/d was given for an hour with mensa uroprotection for the consecutive five days. All but two relapsed patients had response. The number of courses were...
Case Reports
Three Cases of Brain Tumors with Bone Metastasis
Eun Joo Kim, Kyung Duk Park, Eun Sil Dong, Hye Jung Park, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Je Geun Chi
J Korean Pediatr Soc. 1992;35(3):381-389.   Published online March 15, 1992
Medulloblastoma and primitive neuroectodermal tumor(PNET) are relatively common intracranial neoplasms in childhood. Their extracranial metastasis were thought to be rare occurrences. But they are more frequent compared to other intracranial tumors. The most frequent site of metastasis deposits in medulloblastoma is bone, and metastasis to lymph node, peritoneum, liver or lung have been reported infrequently. The authors experienced three cases...
A Case of Holoprosencephaly, Alobar Type
Kyu Sun CHoi, Kang Seo Park, Young Tack Jang, Wan Seob Kim
J Korean Pediatr Soc. 1992;35(3):390-394.   Published online March 15, 1992
A case of Holoprosencephaly, alobar type , was presented here and 13-month follow-up has been made. He had dyspnea, polikilothermia, frequent atypical seizures, hypernatremia & pitressinresponsive Diabetes insipidus as clinical manifeststions. Chromosome studies showed normal male karyotype (46XY). The diagnosis was confirmed by brain CT scan. A brief review of the related literature was made.
Subacute Necrotizing Encephalomyelopathy (=Leight's Disease)
So Young Kim, Heung Ki Min, Byung Churl Lee
J Korean Pediatr Soc. 1992;35(3):395-398.   Published online March 15, 1992
Subacute necrotizing encephalomyelopathy or Leigh's disease is a familial neurodegenerative disorder characterized by focal bilateral and usually symmetric lesions of both gray and white matter in the brain and the spinal cord. The lesions are strikingly similar to those of thiamine deficiency encephalopathy. The diagnosis of subacute necrotizing encephalomyelopathy was usually made by typical clinical manifestation and typical bran CT...
A Case of Dermatomyositis Remitted with Cyclosporin A
Jo Won Jung, Ki Soo Pai, Pyung-Kil Kim, Woo Hee Jung
J Korean Pediatr Soc. 1992;35(3):399-405.   Published online March 15, 1992
Cyclosporin A has highly selective immunce suppressive action through inhibition of the production of interleukin 2 by helper T-cells. A case of dermatomyositis remitted with cyclosporin A in a 2-year-old girl is reported. She was admitted due to progressive weakness of lower extremities and facial flushing. The diagnosis was made by typical clinical findings with aids of laboratory data, electromyographic and...
A Case of Poststeroid Panniculitis
Moon Sang Park, Mee Kyung Nam, Hae Yong Lee, Baek Keun Lim, Jong Soo Kim, Sun Won Hong
J Korean Pediatr Soc. 1992;35(3):406-410.   Published online March 15, 1992
Poststeroid panniculitis occuring after steroid treatment is an extremely rare entity. Multiple subcutaneous, firm, pruritic, tender nodules occur chiefly over the cheeks, arms, and trunk in young children following sudden discontinuation of large dose of steroids. We experiened a case of poststeroid panniculitis in a 2day-old female infant with complaints of multiple subcutaneous nodules on cheeks and neck...
A Case of Poststeroid Panniculitis
Hee Seok Koh, Sha Young Choi, Sung Jin Ha, Oh Kyung Lee
J Korean Pediatr Soc. 1992;35(3):411-416.   Published online March 15, 1992
Poststeroid panniculitis occuring after steroid treatment is an extremely rare entity. Multiple subcutaneous, firm, pruritic, tender nodules occur chiefly over the cheeks, arms, and trunk in young children following sudden discontinuation of large dose of steroids. We experiened a case of poststeroid panniculitis in a 2day-old female infant with complaints of multiple subcutaneous nodules on cheeks and neck for 10 days....
A Case of Incontinentia Pigmenti
Soo Young Kweon, Hyun Joo Choi, Gyung Hee Kim
J Korean Pediatr Soc. 1992;35(3):417-421.   Published online March 15, 1992
Incontinentia Pigmenti is an uncommon genodermatosis that usually affects female infants. The dermatosis may be only a part of more generalized disorder which may affect with great variability the teeth, the eyes, the bones or central nervous system, or may be associated with other malformations or developmental disturbances. We experienced a case of Incontinentia Pigmenti associated with defect of a eye...
A Case of 7q-Syndrome
Ja Hyun Park, Baek Gil Lee, Il Kyung Kim, Jung Sik Min, Chang Hee Choi
J Korean Pediatr Soc. 1992;35(3):422-427.   Published online March 15, 1992
7q-syndrome, although rare, is a well defined syndroime which usually arises de novo. Characteristic clinical features include severe growth and metal retardation, microcephaly, low birth weight, broad nasal bridge with bulbous nasal tip, large, low set ears and genital anomalies. We experienced a male newborn with clinical features suggestive of chromosomal anomaly which was confirmed to be a 7q-(q32-qter) syndrome...
A Case of Right Lung Agenesis
Seung Hyun Seo, Yu Sub Shin, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
J Korean Pediatr Soc. 1992;35(3):428-433.   Published online March 15, 1992
Lung agenesis is the very rare disease which is defined as total absence of the pulmonary parenchyma, its vascular supporting structure, and bronchi beyond the carina. In many cases, there are coexisting anomalies involving the skeletal, cardiovascular, gastrointestinal, and genitourinary systems. Also, severe respiratory infections are common in infancy and may lead to pneumonia and death. When associated anomalies are...
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