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Volume 36(11); Nov 1993
Medical Lecture Course
Neuropeptide and Immune System: Then Role of Substance P
Hae Ran Lee
J Korean Pediatr Soc. 1993;36(11):1495-1501.   Published online November 15, 1993
Original Articles
Re-evaluation of TSH Screening TEST in Neonates
Jin Young Song, Dong Woo Son, Beyong Il Kim, Sei Won Yang, Jung-Hwan Choi, Chong Ku Yoon, Hyung Ro Moon
J Korean Pediatr Soc. 1993;36(11):1502-1506.   Published online November 15, 1993
Five years ago, we made the cut-off value of TSH by dry filter paper method as 15μU/ml to screening congenital hypothyrodism. Since then, 1,210 term neonates, who had no perinatal problems, screening test with this cut-off point. Neonates had been recalled for measurement of serum T4/TSH to rule out congenital hypothyroidism if their TSH value by screening tests reveal more...
Clincal Study on 12 Cases of Neonatal Group B β-Hemolytic Streptococcal Meningitis
Won Jin Kim, Sang Woog Lee, Sang Lak Lee, Myung Sung Kim, Chin Moo Kang
J Korean Pediatr Soc. 1993;36(11):1507-1515.   Published online November 15, 1993
A clinical study was made on 12 cases of neonatal Group Bβ-hemolytic streptococcal(=GBS)meningitis, who were admitted to the department of Pediatrics, Dong-San Hospital, Keimyung University during the period of 3 years from Aug 1989 to Jul 1992. The following results were obtained 1) GBS was cultured in 12 cases(57.1%) among 21 neonatal meningitis admitted during the same period. 2) Male and female ratio...
A Study of Screening for Anemia in 9 Month Old Infants in Well Baby Clinic
Yong Sik Min, Jae Ock Park, Sang Man Shin, Sang Jhoo Lee
J Korean Pediatr Soc. 1993;36(11):1516-1525.   Published online November 15, 1993
Iron deficiency remains the most common cause of anemia in infants and children despite increasing availability of iron-fortified foods. We screened out anemia in 9-month old infants in well baby clinic to know the prevalence of anemia and the weaning status. The results were as follows. 1) Among 345 infants screened, 24 infants(7%) were found to have anemia. 2) The king of anemia...
The Significance of Nucleated Red Blood Cell Counts in Low Birth Weight Neonates
In Ho Song, Weon Kee Lee, Hye Lim Jung, Dong Hyuck Keum
J Korean Pediatr Soc. 1993;36(11):1526-1533.   Published online November 15, 1993
We studied to assess the relationship between intrauterine growth retardation and the increased nucleated red blood cell counts (NRBC) in small for gestational age (SGA) and appropriate for gestational age (AGA) neonates with low birth weight. We also evaluated the nucleated red blood cell counts in low birth weight neonates who had either perinatal asphyxia or hyaline membrane disease (HMD)...
Intravenous Immunoglobulin for Prophylaxis of Neoneatal Sepsis in the Premature Infants
K.H. Hur, S.H. Kim, H.S. Kim, M.J. Chey, K.H. Kim, H.S. Lee
J Korean Pediatr Soc. 1993;36(11):1534-1541.   Published online November 15, 1993
Newborn premature babies have low levels of transplacentally acquired maternal immunoglobulin which is mostly transferred after 32∼34weeks gestation, therefore they may have IgG deficiencies that incerase their susceptibillity to bacterial infection. We preformed this study to determine whether intravenous immunoglobulin (IVIG) therapy improves mortality or infection occurrence rate. From 1 october 1991 to 31 july 1992, 73premature newborn iffants with gestational age≤34weeks...
Comparison between Preterm and Fullterm infants in Neonatal Sepsis
Sung Hee Kim, Kum Hee Hur, Hee Sup Kim, Myoung Jae Chey, Kil Hyoun Kim, Hak Soo Lee
J Korean Pediatr Soc. 1993;36(11):1542-1554.   Published online November 15, 1993
We retrospectively evaluated datas on 61 cases of neonatal sepsis confirmed by clinical symptoms and blood cultures at the NICU of Gil General Hospital From Mar. 1989, to Reb. 1992. The result obtained were as follows : 1) The mean gestational age was 32.7±2.6 weeks in preterm infants, and 39±1.5weeks on term infants. The mean birth weight was 1,701.4±422.4g in preterm infants,...
A Study on Serum Immunoglobulins and Complements in Newborn Infants by Gestational Weeks
Ji Eun Lee, Kyung Hyo Kim, Kyung Hee Kim
J Korean Pediatr Soc. 1993;36(11):1555-1561.   Published online November 15, 1993
The author investigated serum immunoglobulin (IgG, IgA, and IgM) and complements (C3) of cord blood in 74 cases of normal fulterm infants and 50 cases of premature infants. Serum immunolglobulin and complement levels were measured by the single radial immunodiffusion method. The following results were obtained ; 1) The mean serum IgG levels of cord blood in 74 cases of the normal...
Clinical Analysis of Retinopathy of Prematurity
Nam Su Park, Young Myoung Cho, Mu Young Song, Un Jun Hyoung, Jin Oh Lee
J Korean Pediatr Soc. 1993;36(11):1562-1569.   Published online November 15, 1993
One hundred eighty infants with oxygen therapy who were under 2,500gm birth weight or under 37 weeks of gestational age, were examined between January 1990 and November 1992. We performed clinical analysis and results were as follows. 1) Fifty six infants(31.3%) were diagnosed as retinopathy of prematurity. 2) The first examination was performed at 2.5 weeks of ife on average, and the...
Intractranial Hemorrhage in Full-Term Neonates by Ultrasonography
Chang Gyu Lim, Joon Soo Park, Woo Ryong Lee, Jae Ock Park, Sang Mann Shin, Sang Jhoo Lee
J Korean Pediatr Soc. 1993;36(11):1570-1577.   Published online November 15, 1993
Intracranial hemorrhage is the most common neuropathologic finding in premature infants. But in full-term infants, It is less common and rarely causes death. We found out intracranial hemorrhages in 21 full-term neonates by real-time neurosonography and concluded as followings. 1) Among 21 neonates, 17 infants were male and 4 infants were female. 2) In 11(52.3%) infants the hemorrhage was detected within 7...
The Effect of Testosterone on the Response of Grow Hormone Secretion in Cultured Rat Pituitary Cells
Ho Seong Kim, Duk Hi Kim, Deok Bae Park
J Korean Pediatr Soc. 1993;36(11):1578-1582.   Published online November 15, 1993
The effects of testosterone on the pituitary growth hormone(GH) response directly and to hypothalamic growth hormone-releasing hormone(GHRH) were evaluated in vitro using a male pituitary cell monolayer culture system. Wistar male rats were gonadectomized at 22 days of age, and 21 days later their anterior pituitaries were removed and trypsinized for cell dispersion. Testosterone 0.01, 1.0, 10.0nM was added to...
Chronic Idiopathic Intestinal pseudo-obstrucion Syndrome in Childhood
Jae Geon Sim, Jeong Kee Seo, Kui Won Park, Je Geun Chi
J Korean Pediatr Soc. 1993;36(11):1583-1595.   Published online November 15, 1993
Chronic idiopathic intestinal pseudo-obstruction syndrome is a clinical condition induced by an impaired function of intestinal motility. Although its clinical symptoms are those of intestinal obstruction, mechanical obstruction of the intestine cannot be found by vigorous studies, even by operative exploration. We have experienced nine cases of chronic idiopathic intestinal pseudo-obstruction syndrome. It will help in diagnosis and treatment of the...
A Genetic Linkage Study of Wilson Disease in Korean Families
Jong Won Kim, Sang In Kim, Jeong Kee Seo
J Korean Pediatr Soc. 1993;36(11):1596-1612.   Published online November 15, 1993
Wilson disease gene (WND) locus is presumed to be located in chromosome 13q. There are studies on the clinical heterogeneities and variations between ethnic groups in Europe, North America, and the Middle East and it requites the study of another ethnic group, especially Asian population for the confirmation. This study was an analysis of restriction fragment length polymorphism of the Wilson's...
Case Reports
A Case of Transfusion-Associated Gragt-Verus-Host Disease in a Preterm Infant
Hye Jung Joo, Seung Mo Park, Ran Namgung, Kook In Park, Jin Sung Lee, Chul Lee, Dong Kwan Han, Kir-Young Kim, Kwang-Hoon Lee, Kwang-Gil Lee
J Korean Pediatr Soc. 1993;36(11):1613-1620.   Published online November 15, 1993
Graft-versus-host disease is commonly observed after allogeneic bone marrow transplantation but rarely recognized transfusion or solid-organ transplantation. Transfusion-associated graft-versus-host disease can occur in immunosuppressed recipients and immunocompetent transplant recipients. The clinical manifestations of gastrointestinal or hepatic dysfunction, rash and pancytopenia should heighten the physician's index of suspicion for GVHD. Among premature infants, only four cases have been reported to develop...
A Case of Hypodipsic Hypernatremia
Seung Hee Park, Hong Sin Jeon, Sun Hwa Kim, Don Hee Ahn
J Korean Pediatr Soc. 1993;36(11):1621-1625.   Published online November 15, 1993
Hypodipsic hypernatremia is characterized by chronic or recurrent episodes of severe hypernatermia associated with dehydration and a lack of thirst. This constellation of deficits suggests that the syndrome is due to hypodipsia of destruction of the hypothalamic osmoreceptors that regulate thirst and ADH secretion. We report a child with abnormalities of the central nervous system who had hypernatremia and a...
A case of Aberrant Right Subclavian Artery Associated with Innominate Artery Compression Syndrome
Kyung Ho Ko, Young-Ill Park, Churl Young Chung
J Korean Pediatr Soc. 1993;36(11):1626-1629.   Published online November 15, 1993
An aberrant right subclavian artery, the most common congenital anomaly of the aortc arch, is rarely symptomatic during the infancy, if an anomalous origin of a right common carotid artery is also associateda varient of innomiate artery comperssion syndrome. We experienced a case of an aberrant right subclavian artery associated with an anomalous origin of the right common carotid artery in...
A Case of Carbamazepine-Induced Toxic Epidermal Necrolysis
Gi Chan Na, Kyung Seok Kim, Eun Gyeoung Jung, Kyyng Rae Moon, Sang Kee Park, Yeoung Bong Park
J Korean Pediatr Soc. 1993;36(11):1630-1634.   Published online November 15, 1993
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A case of TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of...
A Case of Poststreptococcal Reactive Polyarthralgia
Sung Ho Cha, Byong Soo Cho, Taekyu Hame
J Korean Pediatr Soc. 1993;36(11):1635-1637.   Published online November 15, 1993
Poststreptococcal reactive arthritis/arthralgia is characterized as an evidence of group A beta hemolytic streptococcal infection and does not fulfill the modified Jones criteria for a diagnosis of acute rheumatic fever. We had used to meet the patients with incomplete acute rheumatic fever who had more than 3 items of minor Jones criteria, or arthralgia or arthritis with one or two...
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