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Volume 36(3); Mar 1993
Clinical Lectures
Neonatal resuscitation
J Korean Pediatr Soc. 1993;36(3):303-311.   Published online March 15, 1993
Original Articles
The Variability of Growth Hormone(GH) Response to Growth Hormone-Releasing Hormone(GHRH) according to the intrinsic Growth Hormone Secretory Rhythm in Children with Normal Growth Hormone Reserve
Sei Won Yang, Hyung Ro Moon
J Korean Pediatr Soc. 1993;36(3):312-319.   Published online March 15, 1993
The diagnostic value of GHRH in assenssing GH secretion in biochemical GH suficient short children was examined. GHRH(1㎍/kg i.v bolus) was given to three groups (upslope, trough, downslope) arbitrarily classified according to the basal pulsatile GH secretory pattern before GHRH administration. Cmax following GHRH administration were variable and overlapping. Two children in downslope group, three children in though group, and one...
The Side Effects of Antiepileptic drugs in Epileptic Children Treated withMonotherapy
Kon-Hee Lee, Hae-Sun Yoon
J Korean Pediatr Soc. 1993;36(3):320-327.   Published online March 15, 1993
The goal of therapy of epileptic children is to control of seizures with minimal side effects of antiepileptic drug(AED). The relationship between side effects, serum levels and doses of AED were examined prospectively in 72 epileptic children who received monotherapy with phenobarbital, phenytoin, valproate, or carbamazepine for 6 to 26 months. Our results were as follows: 1) Side effects were observed in...
A Study of Valproic Acid Therapy in Epileptic Children
Hae Jin Choi, Keon Su Rhee
J Korean Pediatr Soc. 1993;36(3):328-337.   Published online March 15, 1993
A study was made on 50 cases of epileptic children who had been observed at the pediatric department of Chungnam National University Hospital and Taejeon Eul Ji Hospital during the period from July, 1986 to June, 1991 The result are as follows : 1) Epilepsy was most frequent in children from 1 yar to 10 year of age(80%). Epilepsy was commoner in...
Obesity in Elementary School Children
Ji Hee Park, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
J Korean Pediatr Soc. 1993;36(3):338-346.   Published online March 15, 1993
Obesity has been implicated as a significant risk factor for multiple medical condition including hypertention, glucose intolerance, hyperlipidemia, hyperisulinemia and fatty liver. Furthermore, obesity in childhood is believed to be a reliable predictor of a similar condition in adulthood. During the recent yars, there has been a rapid rise in the incidence of childhood obesity in Korea due to increased...
Clinical Study on Infants of Diabetic Mothers
Eun Eui Kim, Min Jeong Kim, Yang Sook Choi, Son Sang Seo
J Korean Pediatr Soc. 1993;36(3):347-355.   Published online March 15, 1993
A clinical observation was performed on the 80 cases of neonates born from diabetic mothers among the total of 34,936 neonates delivered at Il Sin Christian Hospital from January 1985 to December 1989. The results were as follows : 1) The incidence of infants of diabetic mothers was 0.23%, among whom gestational diabetic mothers were 63 cases(78.7%) and overt diabetic mothers...
Neonatal Mortality
Min Jeong Kim, Eun Eui Kim, Ock Seung Jeong, Son Sang Seo
J Korean Pediatr Soc. 1993;36(3):356-363.   Published online March 15, 1993
A review of all 919 perinatal deaths occuring in Il Sin Christian Hospital From 91985 to 1989 was carried out. The results of clinical analysis were as follows : 1) The overall perinatal mortality rate was 26.30 per 1,000 birth. 2) The perinatal mortality rate was lowest in the gestation group between 37~41 week and in the weight group between 2,501~4,000gm. 3) The perinatal...
A Clinical Survey of Prematurity
Jee Won Lee, Sang Hee Lee, Ock Seung Jeong, Son Sang Seo
J Korean Pediatr Soc. 1993;36(3):364-370.   Published online March 15, 1993
A clinical observaton was performed on 2,122 cases of premature infants who were admitted to Ilsin Christian during the past 5 years from Jan. 1986 to Dec. 1990. The results were as follows ; 1) The incidence of prematurity was 5.7%, overall mortality rate was 15.8%, and the sex ratio of male to female was 1.5:1. ...
A Study of Serum CK-BB Activity as a Diagnostic Method and a Predictor of Neurologic Out come in Asphyxiated Infants
J Korean Pediatr Soc. 1993;36(3):371-378.   Published online March 15, 1993
Asphyxia is the most important perinatal cause of neurologic morbidity in infants. Recently, elevated levels of CK-BB have been demonstrated in serum after asphyxic insult in infants. To evaluate the possibility of using serial measurements of CK-BB activity as a diagnostic method and a predictor of neurologic outcome in asphyxiatic infants. We studied CK-BB activity in serum of asphyxiated infants(16...
Influenza Epidemic in the Pediatric Patients in Seoul 1991
Hyun Mi Kim, Se Ho Oh, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Young Suhn Kim, Kee Duk Park
J Korean Pediatr Soc. 1993;36(3):379-385.   Published online March 15, 1993
Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january 1991 to March,1991. The results were as follows : 1) Of the total 149 patients, influenza virus were isolated in the 15 cases. : 15 isolates were characterized by the WHO Collaborating Center for influenza : 7...
Inteleukin-6 Level in Systemic Lupus Erythematosus
Young Nae Yim, Dong Soo Kim
J Korean Pediatr Soc. 1993;36(3):386-393.   Published online March 15, 1993
Systemic lupus erythematousus(SLE) is a disease affecting blood vessels and connective tissue, which are damaged by deposition of pathogenic autoantibodies and immune complexes.Although a complex disease, SLE provides a number of insights into autoimmune pathogenesis. Autoimmune disease, in general, is characterized by B cell hyperactivity which results in hypergammaglobulinemia and production of a variety of autoantibodies reactive to organ-nonspecific antigens...
Case Reports
A Case of MELAS Syndrome
J Korean Pediatr Soc. 1993;36(3):394-402.   Published online March 15, 1993
MELAS syndrome is a rae but distinct clinical entity belonging to a group of mitochondrial encephalomyopathies characterized by the tetrad of mitochondrial myopathy, encephalopaphy, lactic acidosis, and stroke-like episodes. We experienced a case of MELAS syndrome in an 8 year-old boy who showed headache, pain of the eyeball, vomiting, stroke-like episodes such as visual disturbance and dysarthria, myoclonic seizure, confusion,...
Changes of Serum IgG4 in Allergic Patients
Soo Young Cho, Sun Kyu Park, Pyoung Han Hwang, Jung Soo Kim
J Korean Pediatr Soc. 1993;36(3):403-408.   Published online March 15, 1993
This study ws performed to evaluate the changes of serum IgG4 level in children with allergic diseases. Serum IgE, IgG and IgG4 level were measured using enyzme immunoassay(IgE) and radial immunodiffusion method (IgG and IgG4) in 21 children with bronchial asthma, allergic rhinitis or urticaria. Eosinophil counts in peripheral blood and the values fo serum IgE were significantly increased in allergic...
Characterization of the Novel Late T Cell Activation Proteins, 519 and 520
Dae-Yeol Lee, Alan M Krensky
J Korean Pediatr Soc. 1993;36(3):409-416.   Published online March 15, 1993
The late T cell activation gene, 519, is expressed in antigen specific, growth factor dependent T cell lines and clones but not in T or B cell tumors, other hematopoietic cells, tonsil, muscle, lung, or liver. Resting peripheral blood ymphocytes(PBLs)express little or no 519mRNA, but levels increase dramatically 5~7 days after activation with alloantigen or mitoen. Four alternatively spliced transcripts...
A Case of Cavernous Lymphangioma in Mediastinum
Jin Kee Jung, Sang Du Lee, Kee Yong Park, Dock Yong Chung, Mi Sun Lee, Jong Gun Kim
J Korean Pediatr Soc. 1993;36(3):417-422.   Published online March 15, 1993
Cavernous lymphangioma in mediastinum is a rare congenital malformation of lymphatic system and is caused by lack of adequate drainage from the sequestrated lymphatic vessels to the venous system due to insufficiency or atresia of the efferent lymphatic channels The authors experienced 10 month-old male patient with cavernous lymphangioma in mediastinum documented by chest CT and open biopsy. The review of the...
A Case of Intracranial Lipoma
Hyun Cheol Lee, Hae Yong Lee, Jae Seung Yang, Beak Keun Lim, Jong Soo Kim
J Korean Pediatr Soc. 1993;36(3):423-427.   Published online March 15, 1993
While lipomas are common in the rest of the rest of the body, intracranial lipomas are rare condition which are usually found in the midline of the brain. The majority of these lesions show few or even no symptoms and hardly ever produce alarming neurological defects. We experienced a case of corpus callosum lopoma in a 7 year old boy, who...
A Case of Incontinentia Pigmenti
Soo Am Chung, Won Rae Kim, Hyung Kun Nam, Jin Sam No, Jung Hee Park
J Korean Pediatr Soc. 1993;36(3):428-433.   Published online March 15, 1993
Incontinentia pigmenti (Bloch-Sulzberger syndrome)is a genetic disease of the skin with generalized ectodermal and mesodermal dysplasia. Skin lesions are uually present at birth or shortly after in the form of eythermatous eruptions with linear vesiculations. The final stage is characterised by irregular macular streaks of brown to slate-grey pigmentation. We experienced five cases of incontinentia pigmenti maternal female relative of a...
A Case of Monozygotic Twin with Dwn Syndrome
Seong Heon Jeon, Choong Hyun Yoon, Young Wook Kim, Ki Bok Kim
J Korean Pediatr Soc. 1993;36(3):434-438.   Published online March 15, 1993
Down syndrome is the most common autosomal chromosomal abnormality characterized by mental and growth retardation, and by various typical features including prominent epicanthal fold, oblique palpebral fissure, flat nasal bridge, short and broad hand, wide toe interspace, etc. The overall incidence has been shown to be 1:800 deliveries, increasing with advancing maternal age. However, twin cses are extremely rare, and...
A Case of Wiskott-Aldrich Syndrome
Dong Un Kim, Seung Hoon Han, Jin Han Kang, Joon Sung Lee
J Korean Pediatr Soc. 1993;36(3):439-446.   Published online March 15, 1993
Wiskott-Aldrich syndrome s an X-linked combined immunodeficency disorder characterzed by severely decreased number of platelets which are small in size, eczema resembling atopic dermatitis and recurrent infection. The serum of the patient contains elevated concentrations of IgA and IgE, whereas the IgG level is usually normal and IgM level is deecreased. The patient also shows skin test anergy and progressive...
Clinical Lectures
Kawasaki Disease
J Korean Pediatr Soc. 1993;36(3):447-452.   Published online March 15, 1993
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