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Volume 37(3); Mar 1994
Pediatrics and Pediatrician's commitment
J Korean Pediatr Soc. 1994;37(3):295-299.   Published online March 15, 1994
Original Articles
The Correlation between the Bone Age and Predicted Adult height, Final Adult Height in the Children with Congenital Adrenal Hyperplasia, Especially 21-Hydroxylase Deficiency
Sei Won Yang, Hyung Ro Moon
J Korean Pediatr Soc. 1994;37(3):300-308.   Published online March 15, 1994
We studied the correlation between the bone age and the predicted adult height, final adult height in the 69 children (30 salt losing form and 39 non-salt losing form) diagnosed as 21-hydroxylase deficiency, retrospectively. The results were as belows; 1) The bone age was similar to the chronological age in the children with salt-losing form (5.3±3.5 years, respectively), but the bone age...
The Effect of Long-Acting Gonadotropin-Releasing Hormone (GnRH) Analog on the Growth Velocity and Final Adult Height in the Children with True Precocious Puberty
Sei Won Yang, Hyung Ro Moon
J Korean Pediatr Soc. 1994;37(3):309-316.   Published online March 15, 1994
The final adult height in the children with true precocious puberty are destined to be short due to excessive bone maturation, compared to the growth velocity, regardless of its etiologies. To improve this final shortness, long-acting GnRH analog have been tried to the children with true precocious puberty. We evaluated the parameters of the growth, including the growth velocity, height...
The Mitral Regurgitation in Patent Ductus Arteriosus (PDA)
Hyang Suk Yoon, Soon Ho Choi
J Korean Pediatr Soc. 1994;37(3):317-321.   Published online March 15, 1994
Mitral regurgitation (MR) was analyzed by Doppler echocardiography, preoperatively and postoperatively, in 59 patients with patent ductus arteriosus (PDA). The ratio of left atrial dimension and aortic root dimension (LAD/LOD) and the maximal velocity of the mitral valve (MV max) were compared in pre, postop group. The degree of the regurgitation was given to the MR group. In preop MR...
Hypercalciuria in High Risk Neonate
Eun Sun Kim, Seung Joo Lee
J Korean Pediatr Soc. 1994;37(3):322-331.   Published online March 15, 1994
The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992. The results were as follows: 1) The incidences of hypercalciuria were 73.9%...
The Metabolic Acidosis and Clinical Outcome in Acute Infantile Diarrhea
Ae Yeon Lim, Yo Ahn Rho, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1994;37(3):332-338.   Published online March 15, 1994
To determine the types of metabolic acidosis using anion gap in acute infantile diarrhea and to correlate it with clinical outcome, we examined 103 infants admitted with acute diarrhea. The serum electrolytes (sodium, potassium, chloride, phosphorus), creatinine, CO2 content and anion gap were measured on first admission day. They were classified group A with normal anion gap (8~16 mEq/L) and...
The Effect of Alfacalcidol in the Treatment of Idiopathic Myelofibrosis in Children
Soon Ki Kim, Jeong Hee Kim, Dae Hyun Lim, Jong Woon Choi, Byong Kwan Son, Hyo Seop Ahn
J Korean Pediatr Soc. 1994;37(3):339-346.   Published online March 15, 1994
Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extramedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposition in IMF using 1, 25-dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F = 1:4) with IMF before and after treatment...
Clinical Observation of Neonatal Group B β-Hemolytic Streptococcal Meningiti
Yeon Chung Chung, Mi Won Kim, Yong Kyu Lee, Yun Jong Kang, Jung Wan Seo, Jin Keun Chang
J Korean Pediatr Soc. 1994;37(3):347-355.   Published online March 15, 1994
Neonatal meningitis caused by the Group Bβ-hemolytic streptococcus was first reported in 1958. In recent years this organism has assumed major importance in the etiology of neonatal infection. In Korea, this organism is likely to play an increasing role in neonatal infection. So this investigation was designed to report the 9 cases of Group B β-hemolytic streptococcus infected neonates admitted to...
Coxiella Burnetii Infection In Patients With Various Diseases
Kyo Sun Kim, Won Young Lee
J Korean Pediatr Soc. 1994;37(3):356-367.   Published online March 15, 1994
Coxiella burnetii(C. burneii) was first recognzed as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatos-plenomegaly,...
The Effect of Long-term Phenobarbital Administration on the Bone Mineral Density of Children
Yoon Suck Suh, Young Guk Kim, Jung Hwa Lee, Kee Hwan Yoo, Joo Won Lee, Young Chang Tockgo
J Korean Pediatr Soc. 1994;37(3):368-375.   Published online March 15, 1994
The long term administration of anti-convulsants on children with convulsive disorders may cause osteomalacia, depending on the dosage, duration, type and combination of anti-convulsants administred. Fifteen children, comprising 10 male and 5 female, dignosed with convulsive disorders and administered with phenobarbital for a long term period of more than 9 months but less than 84 months and 15 healthy children...
Hypophosphatemic Rickets
Jae un, June Huh, Il Soo Ha, Hae Il Cheong, Yong Choi
J Korean Pediatr Soc. 1994;37(3):376-382.   Published online March 15, 1994
The clinical data of 27 patients with hypophosphatemic rickets treated with phosphate and 1 α-hydroxyvitamin D were analysed retrospectively. The median age at diagnosis was 4 years, and the main clinical manifestations were bowleg and short stature. Among total 24 families, 5 families(21%) had X-linked dominant mode of inheritance, 1 family (4%) had autosomal dominant mode and 17 families (71%)...
Clinical analysis of Serum and Urine N-Acetyl-β-D-Glucosaminidase (NAG) in Renal Disease
Yo Han Chung, In Seok Lim, Chul Ha Kim, Byoung Hoon Yoo, Tae Sub Shim
J Korean Pediatr Soc. 1994;37(3):383-389.   Published online March 15, 1994
Recently, NAG activity has gained increasing importance as an aid in the diagnosis of renoparenchymal diseases. Elevation of urine NAG activity has been found to be an indicator of renoparenchymal diseases. To evaluate the diagnostic value of the NAG activity test in the renal disease, we carried out clinical study on 31 cases of renal disease patients who had been...
Clinical Analysis of 29 Cases of Germ Cell Tumor in Children
Tae Geun Song, Gyeong Ah Lee, Jae Sun Park
J Korean Pediatr Soc. 1994;37(3):390-396.   Published online March 15, 1994
Germ cell tumors(GCT) are not infrequently encounted tumor in pediartic age group. In order to study the clinical behaviors of the disease, we reviewed 29 cases of GCT diagnosed and treated at Kosin Medical Center in the period of 7 years from Jan. 1984 to Dec. 1991 and the results are summarized as follows: 1) The age distriution is the highest...
Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy
Hye Young Kang, Kook In Park, Ran Namgung, Chul Lee, Chang Jun Coe, Dong Gwan Han, Tae Sub Chung, Woo Hee Jung
J Korean Pediatr Soc. 1994;37(3):397-404.   Published online March 15, 1994
Functional brain imaging is very important in the diagnosis and evaluation of the various neurologic disorders. In addition to electroencephalography (EEG) and positron emission tomography (PET), single photon emission computed tomography (SPECT) have increasingly gained importance in determination of disturbances in regional brain functions. Both ictal and interictal Tc-99m hexamethyl-propyleneamine oxime single photon emission computed tomography (Tc-99m HMPAO SPECT) was done...
Case Reports
A Case of Subcutaneous Fat Necrosis Of the Newborn
Hong Shin Jeon, Myung Ik Lee, Don Hee Ahn, Hee Jun Yoo
J Korean Pediatr Soc. 1994;37(3):405-409.   Published online March 15, 1994
A 7 day old female baby suffered from perinatal asphyxia and trauma at birth. Subsequently, she had a violeceous subcutaneous plaque on back. The clinical setting, the skin manifestation and the histologic findings of the lesion were diagnostic of subcutaneous fat necrosis of the newborn. Histologic findings revealed fat necrosis with infiltration of inflammatory cells, foreign body giant cells and...
A Case of Rotor Syndrome
Jin Nyoung Park, In Joon Seol
J Korean Pediatr Soc. 1994;37(3):410-415.   Published online March 15, 1994
We experienced a case of Rotor syndrome in an 8 year 6 month old boy who presented with icteric sclera and icteric skin on whole body. His clinical and laboratory characteristics were as follows; 1) Jaundice appeared from several months ago before admission without any clinical disturbance. 2) Direct bilirubin was more increased than indirect bilirubin. 3) Plasma indocyanine green (ICG) kinetics test...
Transient Methemoglobinemia with Acidosis in Newborn
Heng Mi Kim
J Korean Pediatr Soc. 1994;37(3):416-421.   Published online March 15, 1994
methemoglobinemia is an uncommon clinicl problem generally caused by inherited disorders of hemoglobin metabolism or environmental toxicity from oxidizing agents. Since methemoglobin has no oxigen carrying capacity, patient with severe methemoglobinemia may have dangerous hypoxia even when arterial oxygen tension is normal. Degree of exposure to oxidants which are benign for older individuals may produce severe methemoglobinemia in newborns. Acidosis without...
A Case of Congenital Hypoprothrombinemia
Jong Kwang Lee, Hae Won Cheon, Jung Hwa Lee, Kwang Chul Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1994;37(3):422-429.   Published online March 15, 1994
Congenital hypoprothrombinemia is a rare congenital coagulation defect. The clinical signs are manifestation of generalized bleeding tendency such as; mucosal bleeding, hypermenorrhea and post tooth extraction hemorrage. It is associated with prolongation of PT and PTT with normal thrombin time and decreased serum prothrombin level. A case with congenital hypoprothrombinemia was experienced by the authors. A 36 days old male baby...
Congenital Lobar Emphysema
Cheal Gee Kim, Do Hee Choi, Jin Bok Hwang, Chang Ho Han, Hye Li Chung, Young Dae Kwon
J Korean Pediatr Soc. 1994;37(3):429-433.   Published online March 15, 1994
We had experienced a case of congenital lobar emphysema in a 3months old male infant. Chief symptoms included tachypnea, respiratory difficulty, cyanosis. Chest X-ray or chest CT scan revealed extensive emphysematous changes of the right upper and middle lobes, compression of the right lower lobe and shifted of mediastinum to the left side. This condition was appeared in the absence...
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