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Purpose : Applying the present growth curve(established in 1985) in practice, we noticed some difference. And so, we performed this study to know that is it necessary to revise the present standard data in Korea. Methods : We checked the height and weight of 208 children of one primary school in Seoul. And also, we measured arm circumference and triceps thickness... |
Purpose : Intrabventricular hemorrhage is a common neuropathologic finding in premature and low birth weight infants. It is deeply related with neonatal death and neurologic sequelae. We want to know the incidence and the relating factors of intracranial hemorrhage in premature and low birth weight infants. Methods : We performed craniosonography in 170 premature and low birth weight infants in 3-7... |
Purpose : Stable microbubble rating test(SMR) plays an important role in the clinical course and the prognosis of respiratory distress syndrome(RDS) patients, because SMR can be easily performed and it can predict quickly the neonatal RDS. After the success of the pulmonary surfactant replacement therapy in RDS infants by Fujiwara and co-workers in 1980, many supporting studies were presented and... |
Purpose : To study the safety and immunogenicity of new live attenuated varicella vaccine (MAV/06strain) in normal healthy children and immunocompromized children in Korea. Methods : Blood samples for fluorescent antibody to membrane antigen(FAMA) assay were taken before the vaccination among seven hundred forth five healthy children and twenty two nine immunocompromised children. One hundred and seventy seven children and twenty... |
Purpose : Because of increased measles incidence in Korea during 1993 and the recent finding of genomic differences between vaccine virus and contemporary wild measles viruses, we conducted a measles vaccine efficacy study involving children ages 1 to 5 yeark, with the demographic analysis of patients brought to the hospitals during measles outbreak that had occurred 1993 in Seoul and... |
Purpose : In front of the nation wide project of 15-year-old girl rubella immunization plan we performed a seroepidemiologic study to find out the age specific prevalence rate of rubella antibodies in the Southern Central Korea. Methods : Total 600 serum specimens from 20 cord bloods and patients of 400 children and 180 adults were obtained at the Geyongsang National University... |
Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis. Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100... |
Purpose : Adrenocorticotropic Hormone(ACTH) therapy is useful in the treatment of patients with infantile spasm. However, serious side effects including Cushing syndrome, infections, hypertension, and electrolyte imbalance must be encountered. Moreover, hypertrophic cardiomyopathy in association with ACTH therapy has recently reported. We performed thiw study to evaluate the effect of ACTH on heart muscle. Methods : We administered ACTH subcutaneously to... |
Purpose : The relative incidence of fetal cardiac anomalies and associated extracardiac anomalies in Korean fetuses were studied. Methods : Findings in fetal echocardiography and autopsy were reviewed using 129 fetuses with cardiac anomalis detected at a gestational period under 38 weeks from 1991 Jan. to 1994 June. Results : The most common fetal cardiac anomaly was isolated atrial septal defect(28 cases... |
Purpose : Homatopoietic stem cells, which have the ability to undergo self-renewal as well as to develop into multipotential differentiations, have been consistantly demonsteraten in human umbilical cord blood. Recently, there have been a few studies using the umbilical cord blood as a source of stem cell transplantation. However it remains unclear whether umbilical cord blood in safe with regards to... |
Purpose : Insulin dependet diabetes mellitus(IDDM) is a rare disease in children, but it will progress rapidly and falls into a diabetic ketoacidosis or coma. Unfortunately, the characteristics and prevalence rate of children with IDDM are not well known in Korea. With a view to recognizing its importance, we studied clinical course of IDDM patients in Chonbuk province, Korea. Methods : From... |
Purpose : The ability to respond to pharmacologial provovation tests may not necessary reflect actuaol secretory patterns of growth hormone. Therefore, the aim of this study in to evaluate the 24-h IC-GH and compare this with their resposnses to standard pharmacological provocation tests for growth hormone comcentrations and to evaluate peak frequency and peak amplitude during 24-h IC-GH in children... |
Steroid-induced lipodystrophy is preduced by long-acting injectable glucocortiocoids (triamcinolone acetonides) within three weeks after intramuscular injection. It can be caused by inappropriate use of injectable steroids. Although it is recovered spontaneously without medication or plastic surgery, it may lasts for several years. Recently we experienced four cases of steroid-induced lipodystrophy and present a brief review of related literatures. |
A 9-year old boy suffered from fever 20 days. He lived in rural area near farms rearing cows, goats, sheep. He had fever for 20 days with mild respiratory symptom, hepatosplenomegaly and agranulocytosis. Coxiella burnetii infection was confirmed by the blood culture and demonstration of the specific antibodies in the indirect fluorescent antibody test. Four weeks later, agranulocytosis was improved... |
The fetal hydantoin syndrome is broad range of morphologic and developmental disorder in infant born of epileptic mothers exposed to hydantoin during pregnancy. We experienced a case of fetal hydantoin syndrome in a male neonate who had cleft palate, cleft lip, hypertelorism, TOF, finger hypolasia with prenatal history of exposure to diphenylhydantoin. We presented this case with brief review of literatures. |
Vertical transmission of hepatitis C virus(HCV) has been reported recently. The authors experienced one case of vertical transmission of HCV in infant of the mother who had active hepatitis C durig pregnancy. At delivery, HCV RNA(+), IgG anti HCV Ab(+), IgM anti HCV Ab(+), mile elevation of liver aminotransferase level and mile fatty liver of ultrasonography were found in the... |
A 9-year-old girl presented with primary hypothroidism have been followed by the development of hyperthyroidism. The diagnosis of primary hypothyroidism had been made by clinical manifestation, elavated serum thyroid-stimulating hormone level, antithyroglobulin antibody and antimicrosome antibody. Five and a quarter years later, the diagnosis of hyperthyroidism had been made by clinical maifestation such as enlargemetn of thyroid gland, tahcycardia, increased... |
The β-thalassemia minor is a hereditary microcytic, hypochromic anemia characterized by decerased producion of β-globin polypeptide chain. The β-thalassemia minor should be clinically differentiated from iron deficiency anemia. The thalassemia are common in the Medeterranean region, the Middle Ease, the Africa, Indea, and Thailand, but rare in Korea. The authors experienced two cases of familial β-thalassemia minor 4-year 7-month-old female patient and... |
Tuberculosis may affect Iymphnodes of any part of the body as a primary infection or secondary to lymphatic or hematogenous dissemination. But the diagnosis of tuberculous mesenteric lymphadenitis is often difficult to establish, because symptoms and signs are often quite vague and laboratory and radiologic findings ard unhelpful. We have recently experienced a case of tuberculous mesenteric lymphadenitis clinically presenting as... |