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Volume 38(9); Sep 1995
Original Articles
Measurement of Malonate Concentration using Malonyl-CoA Synthetase and its Relationship with Disease
Seung-Kyoo Han, Jeung-Kyu Kim, Seung-Ryeoul Paik, Chung-Soon Chang, Yu-San Kim
J Korean Pediatr Soc. 1995;38(9):1167-1175.   Published online September 15, 1995
Purpose : Malonate is an effective competitive inhibitor of succinate dehydrogenase isolated from brain and other organs. It has been shown that malonate level is proportional to the growth of fetal rat brain. However, little is known about its biological effects on central nervous system and other organs. In this communication. we have measured malonate levels in neonates and patients...
Serum 2-microglobulin and Retinol Binding Protein and Urine 2-microglobulin and 1-microglobulin in Early Neonatal Period
Jong Duck Kim, Jae Kak Choi, Yong Hwoe Moon
J Korean Pediatr Soc. 1995;38(9):1176-1184.   Published online September 15, 1995
Purpose : For evaluation of usefulness of the serum .2-microglobulin(B2MG), retinol binding protein(RBP), urine 1-microglobulin(A1MG), and B2MG on neonatal renal function and renal tubular injuries, we detected and compared these values in 20 neonates. Methods : They were grouped into premature neonate, gestational age was 30-50 weeks(group Ⅰ), and full term neonate, gestational age was 38-40 weeks(group Ⅱ), The group Ⅱ...
Riboflavin Status of Normal Newborn Infants and the Changes of Riboflavin During Phototherapy in Hyperbilirubinemic Newborn Newborn Infants
Eun Ae Park, Gyoung Hee Kim
J Korean Pediatr Soc. 1995;38(9):1185-1192.   Published online September 15, 1995
Purpose : Riboflavin is the most important water soluble vitamin in infant nutrition. Riboflavin is converts to flavin mononucleotide (FMN), Flavin adenine dinucleotide(FAD) and then, participiates in the metabolism of energy, protein cellular oxidation-reduction reactions as a cofactor of reactions. Also riboflavin, a light sensitive vitamin, has a maximum absorption spectrum at a wave length similar to that at which...
Clinical Observations of Transient Idiopathic Hypocalcemia
Jeong Nyun Kim, Mi Jung Park, Duk Hi Kim, Ho Sung Kim
J Korean Pediatr Soc. 1995;38(9):1193-1200.   Published online September 15, 1995
Purpose : In concern of diagnosis and treatment of transient idiopathic hypocalcemia, a major cause of infantile, we studied the onset of age, clinical characteristics, laboratory findings, and duration of treatment and recovery of transient idiopathic hypocalcemia. Methods : The author observed 19 infants with transient idiopathic hypocalcemia who had been admitted to Yonsei university hospital due to convulsion for 4...
Natural Anti-PRP Antibody Levels to Haemophilus Influenzae Type b(Hib) and Changes of Antibody Levels after Three Doses of Vacination
Eun Sun Yoo, Eun Ae Park, Gyoung Hee Kim
J Korean Pediatr Soc. 1995;38(9):1201-1209.   Published online September 15, 1995
Purpose : The Haemophilus influenzae type b(Hib) was the most common cause of meningitis and invasive bacterial disease mainly in children 2 months to 5 years old in the United States. The conjugated Hib vaccines have recently been licensed by the US Food and Drug Administration for routine use in infants beginning at 2 months of age, and the Infectious...
A Study of Relationship between Bronchial Hyperreactivity (BHR) and Atopic Findings in Mycoplasma pneumoniae Pneumonia
In Kyeong Seo, Weon Jeong Bae, Jae Ook Lee, Im Ju Kang
J Korean Pediatr Soc. 1995;38(9):1210-1219.   Published online September 15, 1995
Purpose : The respiratory infection due to Mycoplasma pneumoniae among school aged children and adolescents was recognized as an important cause of wheezing or BHR. This study was performed to evaluate relationship between BHR to Mch inhalation challenge and atopic findings in M. pneumoniae pneumonia. Methods : 61 patients with M. pneumoniae pneumonia who were admitted to the department of Pediatrics,...
Results of the Mechanical Valve Replacement in the Right Side of the Heart in Children
Hyeon Jin Park, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim
J Korean Pediatr Soc. 1995;38(9):1220-1231.   Published online September 15, 1995
Purpose : We performed this study in order to evaluate the outcome of the mechanical valve replacement in the right side of the heart in children. Methods : Retrospective analysis of the clinical records of 26 patients who had undergone a right sided valve replacement between October 1986 and September 1992 at Seoul National University Children뭩 Hospital. Results : Twenty six children...
Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
J Korean Pediatr Soc. 1995;38(9):1232-1241.   Published online September 15, 1995
Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to...
Analysis of Radiologic Findings in Children with Urinary Tract Infection
Won Suk Kuk, Il Kyung Kim, Ho Seong, Chang Hee Choi
J Korean Pediatr Soc. 1995;38(9):1242-1252.   Published online September 15, 1995
Purpose : Because some patients with urinary tract infection (UTI) may combine vesicoureteral reflux and progress to reflux nephropathy, the early diagnosis and treatment of UTI are important. We have performed this study to recognize the meaning of the radiologic examination centering around technetium 99m- labelled dimercaptosuccinic acid renal scan(DMSA scan) in pediatric UTI patients. Methods : We have studied 55...
Iron Deficiency Anemia in Infants
Woon Ja Chung, Kue Sook Kim, Mi Kyung Kim, Shin Na Kim
J Korean Pediatr Soc. 1995;38(9):1253-1261.   Published online September 15, 1995
Purpose : To study the incidence of iron deficiency anemia we conducted blood tests with questionnaire regrarding weaning status. We tried to figure out the relation between iron deficiency anemia and financial and educational levels of their parents. The purpose of this study is to emphasize the importance of screening for iron deficiency anemia at well baby clinic and educate mothers...
Relation between Airway Responsiveness and Serum IgE in Children with History of Asthma, Allergic Rhinitis, and Atopic Dermatitis
Su- Jin Park, Ki-Hyun Chung, Wan-Seob Kim, Kang-Seo Park
J Korean Pediatr Soc. 1995;38(9):1262-1269.   Published online September 15, 1995
Purpose : Asthma is known to be related to serum IgE levels. But it is not ascertained whether there is a relation between serum IgE levels and airway hyperresponsiveness to methacholine challenge. For this reason we studied the relation between the serum IgE levels and airway hyperresponsiveness or responsiveness in regard to asthma, allergic rhinitis, and atopic dermatitis. Methods : The...
Case Reports
Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister
Jin Hwa Jung, Jeong Ho Lee, Yong Sub Kim, Jong Dae Jo
J Korean Pediatr Soc. 1995;38(9):1270-1275.   Published online September 15, 1995
We recently experienced three cases of Rotor syndrome in monozygotic twin brothers and their elder sister. The only clinical manifestation was persisting mild jaundice for several years. In all three cases serum bilirubin, mainly of direct reacting was increased with normal liver function and normal hepatic histology without pigmentation by needle liver biopsy. Indocyanine green test showed marked serum retention after...
Two Cases of Conjoined twins
Hyung Jo Jung, Swi Sook Kim, Il Kyung Kim, Ho Sung, Chang Hee Choi, Hyo Jin Lee
J Korean Pediatr Soc. 1995;38(9):1276-1282.   Published online September 15, 1995
Conjoined twins are known to be very rare congenital malformations and may be viewedas examples of incomplete twining. Because of their associated anomalies, particularly of cardiovascular system, they usually survive only short postnatal period. We have experienced 2 cases of conjoined twins. One case of dicephalus dipus dibrachius and another case of thoracopagus are presented with brief review of literature.
A Case of Acyclovir Induced Acute Tubular Necrosis
Mi Ya Park, Mee Kyung Namgoong, Hwang Min Kim, Baek Keun Lim, Sun Hee Jung
J Korean Pediatr Soc. 1995;38(9):1283-1287.   Published online September 15, 1995
Acyclovir is generally regarded as a safe and highly effective antiviral agent in normal, as well as in immunocompromised hosts. Major renal complication was unusual. However, reversible renal dysfunction has been reported. The impairment of renal nephropathy resulting from crystal formation in the renal tubules or the collecting ducts. But we experienced a case of immunocompetent patient who developed severe...
A Case of Spontaneously Remitted Congenital Minimal Change Nephrotic Syndrome
Tae Sun Ha, Kyung Hee Lee, Beom Soo Park, Heon Seok Han
J Korean Pediatr Soc. 1995;38(9):1288-1292.   Published online September 15, 1995
Nephrotic syndrome is a condition with severe proteinuria, hypoalbuminemia, and edema. When the syndrome develops within the first 3 months of life, it is generally considered as congenital and the overall outcome in this group seems to be worse than in miniaml change lesion that occurs at an older age regardless of the pathologic findings. A female infant with congenital nephrotic...
Arthrogryposis Multiplex Congenita in Siblings
Kyoung Hee Choi, Jeong Ah Park, Kyoung Sim Kim, Ki Bok Kim
J Korean Pediatr Soc. 1995;38(9):1293-1298.   Published online September 15, 1995
Arthrogryposis multiplex congenita is a rare congenital disorder characterized by multiple fixed-joint deformities of the upper and lower extremities. Most cases are sporadic, although rare cases of familial recurrence are reported worldwide. Recently, we experienced 2 cases of arthrogryposis multiplex congenita in a family (a brother and a sister). They were born with micrognathia, low set ears, broad and short...
A Case of Meckel-Gruber Syndrome
Hye Jin Lee, Eun Ae Park, Gyoung Hee Kim
J Korean Pediatr Soc. 1995;38(9):1299-1303.   Published online September 15, 1995
We report a case of male neonate that showed multiple congenital anomalies that could be designated as Meckel-Gruber syndrome. The principle signs of Meckel-Gruber syndrome are encephaolcelem, polydactly, and polycystic kidneys with normal karyotype. Due to rarity of the Meckel-Gruber syndrome, the cause was still unknown. At present, autosomal recessive is thought to be as one of the causes. This malformation...
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