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Volume 39(4); Apr 1996
Medical Lecture Courses
Immunization and Antibody Responses to Haemophilus influenzae Type b Polysaccharide in Children
Kyung Hyo Kim
J Korean Pediatr Soc. 1996;39(4):445-454.   Published online April 15, 1996
Clinical Application of Molecular Cytogenetics
Won Bae Lee
J Korean Pediatr Soc. 1996;39(4):455-460.   Published online April 15, 1996
Clinical Lecture
Pediatric Endoscopy for the Diagnosis and Management of Gastrointestinal Diseases in Children
Jeong Kee Seo
J Korean Pediatr Soc. 1996;39(4):461-474.   Published online April 15, 1996
Original Articles
Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants
Hwa Young Jang, Haeng Mi Kim
J Korean Pediatr Soc. 1996;39(4):475-481.   Published online April 15, 1996
Purpose : This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. Methods : For a total of ten VLBW infants who had...
Evaluation of Pulmonary Function Test by Pneumotachography and Passive Expiratory Flow-volume Technique in Newborns with Respiratory Diseases with Respiratory Diseases
Hye Jin Lee, Kyung Hyo Kim, Gyoung Hee Kim
J Korean Pediatr Soc. 1996;39(4):482-490.   Published online April 15, 1996
Purpose : Pulmonary function test is an important diagnostic tool in neonatal intensive care. These tests provide a detailed assessment an infant's pulmonary status that can be used in several ways: to monitor the progression of lung disease, to streamline ventilator management, and to assess the infant's response to new treatments, such as surfactant replacement therapy or bronchodilator. The purpose...
A Measurement of Mumps Specific IgG & IgM Antibody in the Seraof Mumps Vaccinated Healthy Children
Yeoung-Bong Park, Eun-Gyeoung Jung, Kyung-Rae Moo
J Korean Pediatr Soc. 1996;39(4):491-496.   Published online April 15, 1996
Purpose : To evaluate the efficacy and need for boosting of mumps vaccine, we measured the degree of immunity of previously vaccinated healthy children with the age from 15 months to 15 years. Methods : We measured mumps specific IgG & IgM antibody titers of 96 children, vaccinated at the age of 15 months, with the age from 15 months to...
Ultrasonography for Diagnosis of Acute Appendicitis in Children
Mi Kyoung Lee, Chang Sung Im, Sun Mi An, Chang Hee Kim, Dong Jin Lee, Jung Hyouk Kwon
J Korean Pediatr Soc. 1996;39(4):497-502.   Published online April 15, 1996
Purpose : Accurate clinical diagnosis of acute appendicitis is more difficult in children since they may not be able to communicate their complaints adequately, and findings on physical examination may be nonspecific.The uncertainty in diagnosis may lead to a delay of surgery or to unnecessary laparotomy. Prompt diagnosis is important due to their complications such as perforation, abscess formation, and...
A Study of Radiocontrast Media Induced Nephrotoxicit
Chong Guk Lee, Jae Ho Cho, Se Wook Oh, Yong Won Park
J Korean Pediatr Soc. 1996;39(4):503-511.   Published online April 15, 1996
Purpose : This study was aimed at determining whether tri-iodinated compounds with greater solubility and low osmolality, Na or meglumine ioxaglate(Hexabrix 320, Guerbet Lab., France) had deleterious effects on renal function after cardiac angiography for the evaluation of congenital heart disease(CHD) and determining whether correction of dehydration using iv hydration given before cardiac angiography were effective in prventing renal dysfunction. Methods...
A Study of Tubular Fluid Effects to Dysmorphic Urinary RBCs in Glomerular Hematuria
Byung Min Choi, Hyun Joo Kwak, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1996;39(4):512-521.   Published online April 15, 1996
Purpose : Urinary red blood cell morphology has been used to localize the site of hematuria in the urinary tract. But the pathologic mechanism for dysmorphic urinary red blood cells remains undefIned. Our study was undertaken to investigate the mechanism of dysmorphic urinary RBCs in glomerular hematuria. We have attempted to reproduce in vitro the changes that occur in red cell...
A Clinical Study on Infantile Spasms with Prednisolone Therapy
Hye Sun Yoon, Young Hoon Choi, Ho Suk Lee, Yong Mook Choi, Sa Jun Chung
J Korean Pediatr Soc. 1996;39(4):522-529.   Published online April 15, 1996
Purpose : Infantile spasms are considered malignant epilepsy of infancy. Primary objectives of treatment are complete control of seizure attack and prevention of further brain damage. The aim of this study is to assess prednisolone(PDL) efficacy in infantile spasms. Methods : From June 1985 to July 1994, 20 children with infantile spasms who were diagnosed at Kyung Hee University Hospital and were...
Periventricular Leukomalacia: Electroencephalographic Features and Neurodevelopmental Outcome
Hee Jung Chung, Young Rae Kim, Mun Chul Kim
J Korean Pediatr Soc. 1996;39(4):530-542.   Published online April 15, 1996
Purpose : Periventricular leukomalacia(PVL) is associated with the characteristic neurologic sequale of spastic diplegia or quadriplegia, and cortical blindness. So early diagnosis of PVL in the neonatal period is of importance because of the prognostic implications of this lesion. Novotny et al reported that Positive Rolandic Sharp waves(PRS) on the EEGs was a marker of PVL because most infants who...
Serum Secretory CD4 and CD8 Levelsin Kawasaki Disease
Kyung Hyo Kim, Young Mi Hong, Gyoung Hee Kim
J Korean Pediatr Soc. 1996;39(4):543-551.   Published online April 15, 1996
Purpose : Kawasaki disease (KD) is an acute febrile illness of infancy and early childhood characterized by diffuse vasculitis. Although the disease is generally self-limited, up to 25% of untreated patients with KD may develop coronary artery abnormalities. The acute phase of KD is characterized by marked activation of the immune system leading to increased cytokine production by immune effector...
Serial Changes of Blood Glucose Levelsin IDDM Patients Using Intermediate-acting Insulin only Therapy
Ye Sik Kim, Mi Jung Park, Duk Hi Kim
J Korean Pediatr Soc. 1996;39(4):552-557.   Published online April 15, 1996
Purpose : We investigated the clinical characteristics of IDDM patients, treated with NPH only, and evaluated current problems by measurement of serial blood glucose, insulin, C-peptide for 12 hours after administration of intermediate-acting insulin. Methods : We studied 19 IDDM patients who had been diagnosed and followed up on a regular basis at Severance hospital. They were assigned into 2 groups, one(HbA1c...
Case Reports
A Case of Respiratory Syncytial Virus Infection Presented with Apnea
Eun Ha Choi, Seong Hee Jang, Young Min Ahn
J Korean Pediatr Soc. 1996;39(4):558-561.   Published online April 15, 1996
Respiratory syncytial virus(RSV) is currently implicated as the most common and otentially serious viral respiratory pathogen of young infants. Apnea in association with RSV infection occurred in about 18% of the infants. Premature birth and a young postnatal age were risk factors for development of apnea with RSV disease. We experienced a case of RSV infection in a 37 day-old...
Isolated Splenic Infarction in a Girl with Systemic Lupus Erythematosus
Kyung Ran Park, Hee Eun Lee, Yun Ae Jeon, Il Soo Ha, Hae Il Cheong, Joong Gon Kim, Yong Choi
J Korean Pediatr Soc. 1996;39(4):562-566.   Published online April 15, 1996
Splenic infarction is a rare disease and usually detected as a complication of SBE, atrial fibrillation, hemoglobinopathy, or myeloproliperative disorders. Although thrombotic event, such as deep vein, cerebral or renal thrombosis, is a frequent complication of SLE, there have been only a couple of cases documenting splenic infarction complicated in SLE. This is, to our knowledge, the first case report...
A Case of Congenital Lipoid Adrenal Hyperplasia
Seo-Jeong Kim, Joo-Sik Choi, Kyu-Hyung Lee, Dong-Kyu Jin
J Korean Pediatr Soc. 1996;39(4):567-571.   Published online April 15, 1996
Congenital lipoid adrenal hyperplasia is the most severe form of CAH, leading to impaired production of all steroid hormones including glucocorticoids, mineralocorticoid, and sex steroids. The affected individuals are all phenotypically female with a severe salt-losing syndrome that is fatal if steroid replacement is not begun immediately after birth. The lesion of this disorder has been suggested to be in...
A Case of Acute Viral Myositis
Jong-Hoon Kwak, Kyung-Yil Lee, Ji-Whan Han, Sung-Soo Hwang, Jae-Kyun Huh, Kyong-Su Lee
J Korean Pediatr Soc. 1996;39(4):572-576.   Published online April 15, 1996
Diffuse myalgia is common in transient systemic viral infections but overt myositis, with weakness and signs of muscle inflammation, rarely accompanies viral infection in chidren. We describe a 8-year-old boy with severe myalgia and tenderness in both lower extremities, whose unusual skeletal muscle uptake on Technetium-methylene diphosphate bone scan helped to diagnosis of myositis. Clinical course, muscle-derived enzyme studies(AST, ALT,...
A Case of17α-Hydroxylase Deficiency
Yong Kyu Lee, Yun Jong Kang, Chan Young Pak, Soo Young Choi, Moon Soo Park
J Korean Pediatr Soc. 1996;39(4):577-584.   Published online April 15, 1996
A 12-year-old girl with hypertension, hypokalemia, cystic ovaries and absence of secondary sexual development is presented. Hormonal study revealed very low levels of cortisol, testosterone, estrogen, and high levels of progesterone, deoxycorticosterone, corticosterone, FSH and ACTH. Following treatment with dexamethasone and estrogen, the levels of the latter group remarkably decreased. Serum potassium level and blood pressure also became normal. With...
A Case of Chronic Granulomatous Disease Associated with Pyogenic Liver Abscess
S.K. Lee, J.H. Kim, S.Y. Kim, E.T. Oh, H.J. Kang, K.S. Kim
J Korean Pediatr Soc. 1996;39(4):585-590.   Published online April 15, 1996
We have experienced a case of chronic granulomatous disease associated with pyogenic liver abscess in 10 years old male Chronic granulomatous disease(CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. It was diagnosed by clinical finding and laboratory examination including NBT test. Pyogenic liver abscess in old...
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