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Purpose : Since Caffey et al. first described the anomaly in pelvis among the Down patients, decreased iliac and pelvic indexes have been helpful in diagnosing the syndrome. For Korean cases, however, no definitive data are available as yet, prompting us to evaluate the pelvic changes in Korean Down's patients. Methods : Subjected to this study were 68 children with Down's syndrome. As... |
Purpose : The pertussis vaccines are divided into whole-cell vaccine and acellular vaccine. Purified component acellular pertussis vaccine, originally developed in Japan, has been used for primary immunization series in Korea since 1984. We performed this study to evaluate the prevalence of pertussis antibodies following vaccination with acellular pertussis vaccine. Methods : We randomized 80 children who were immunized according to vaccine schedules... |
Purpose : Enzyme immunoassay (EIA) is now a widely used technique. We have described the application of enzyme amplification (sensitive ELISA) in the field of immunoassays of pediatric population. There are two issues with the sensitive ELISA. First is that one can minimize the serum volume, an important concern for pediatricians. The second is the problem of background signal. We demonstrate that it... |
Purpose : Most of invasive Haemophilus influenzae diseases occur in children under 5 years of age, and are due almost exclusively to type b strain. Although antibodies to several surface antigens of H.influenzae play a role in conferring immunity, antibody to the type b capsular polysaccharide appeared to have the most important protective functions. However, the antibody response to vaccines or natural... |
Purpose : Pneumothorax, pneumomediastinum and subcutaneous emphysema rarely complicate pediatric respiratory disease such as bronchial asthma, bronchiolitis, bronchopneumonia. But physicians unfamiliar with natural history of these complications may feel that surgical intervention is necessary. So this study was done to to recognize the pulmonary air leak syndrome associated with respiratory disease in infancy and childhood. Methods : I reviewed retrospectively the medical... |
Purpose : Most patients suffer from croup only once in a life time. However, a small group of patients suffer from it several times. A type of croup from which they suffer more than 3 times is called recurrent croup. The cause of recurrent croup has not been clearly described, but in recent years the allergic reaction is considered as a... |
Purpose : We investigated the occurrence rate of recurrent abdominal pain(RAP) in general population of elementary school children, accompanied symptoms, symptomaggravating factors such as emotional stresses, food and personality characters, which time of day the pain develops and whether they visited hospital for RAP. Methods : From 1995. 4. 27. to 1995. 5. 12. questionnaires were given to the parents of 1,783... |
Purpose : Cyclic vomiting syndrome is characterized by repeated, unpredictable, explosive and unexplained bouts of vomiting and recur after intervals of uncertain length. In the absence of either known etiology or pathogenesis, deciphering the mystery of cyclic vomiting syndrome presents us with a daunting clinical challenge. As we seek to understand this mysterious vomiting disorder of unknown etiology and pathogenic mechanism,... |
Purpose : There have been controversies on the hematologic effects of antiepileptic drugs according to the mono or combined antiepileptic therapy. We evaluated the hematologic changes of the patients who have been taking antiepileptic drugs for more than 4 months and compared the changes of these values according to the mono or combined therapy. Methods : From May,1989 to April,1995, we had examined the blood... |
Purpose : Febrile convulsion is classified as simple or complex type, the latter being characterized by frequent recurrence of febrile convulsion itself and progression to epilepsy. This study was performed to seek the predisposing factors to complex febrile convulsion. Methods : This study was retrospectively undertaken to review medicalrecords of 472 children under 15 years of age with febrile convulsions, who were... |
Purpose : This study is to assess the occurence rate, severity, and duration of the back pain after lumbar puncture. Methods : The occurence rate, severity and duration of the back pain that developed after lumbar puncture were recorded prospectively in patients with aseptic meningitis who had been admitted to the department of Pediatrics, St. Benedict Hospital in Pusan, from May 1993 to July... |
Purpose : Cough variant asthma is characterized as a persistent, nonproductive cough with minimal or no wheezing and dyspnea. Cough variant asthma can be overlooked or misdiagnosed because it is a common problem amongst all ages that frequently is unrecognized. The patho-physiology of cough variant asthma is still unclear. Methods : To characterize the pathophysiological abnormalities of cough variant asthma, bronchial provocation tests with methacholine... |
Malaria is a protozoan disease transmitted by the bite of female Anopheles mosquitoes. Only four species of Plasmodium can infect human, which are P.vivax, P. ovale, P. malariae, and P. falciparum. We experienced four cases of the imported falciparum malaria in children who were admitted due to fever, vomiting, diarrhea, abdominal pain, lethargic state, and/or altered mentality after traveling Kenya and Tanzania without... |
Ischemic enteritis is caused by embolism or thrombosis of superior mesenteric artery and nonocclusive ischemia. Mesenteric venous thrombosis, drugs, and vasculitis are less frequent etiologic factors. In children, occlusion of microcirculation by fibrin thrombi initiated by endotoxemia may be an etiology. Severe abdominal pain, vomiting, and diarrhea with evidence of gross or microscopic bleeding are common presenting symptoms. Angiography may be... |
Hereditary stomatocytosis is a rare congenital hemolytic anemia, named after mouth shaped or stomatocytic erythrocyte morphology. In this report, we present a case of a hereditary stomatocytosis in a 1 month old boy. During the initial identification process, we overlooked the morphology of the RBC in peripheral blood smear and tentatively diagnosed it to be a hereditary spherocytosis case. In order to... |
Narcolepsy is a serious, lifelong, disabling disorder characterized by a tetrad of symptoms including excessive daytime sleepiness, cataplexy, hypnagogic hallucination, and sleep paralysis. We experienced a 14 year old boy with a narcolepsy diagnosed by typical clinical symptoms above mentioned and multiple sleep latency test. A brief review of the related literatures was also made. |
Neurofibromatos is originally described by von-Recklinhausen in 1882, is often depicted as a chronic progressive hereditary disease characterized by pigmentation of the skin, cutaneus lesions, and numerous tumors developing in association with elements of both the central and peripheral nervous tissue. Mesenteric involvements in neurofibromatosis are very rare in childrens. We experienced a case of neurofibromatosis with multiple neurofibromas on mesentery in... |
Arteriovenous malformation in the gastrointestinal tract is very rare in children. However, when present they are frequently a source of either acute and massive, or chronic occult hemorrhage, and may be difficult to diagnosis. In reviewing Korean literature, only 2 cases has been reported in adults. We have experienced a rare case of arteriovenous malformation in a 1 year and 10 month-old female... |
Juvenile granulosa cell tumor(JGCT) is one of the sex cord stromal tumors of the ovary ocurring in the first two decades of life. These tumors are different from adult granulosa cell tumor(AJCT) with regard to clinical and pathological fetures. Follicles are often irregular, Call-exner bodies are rare, and luteinization is frequent. The tumor may besolid, cystic, orboth. The most common presenting... |
Aneurysm of the pulmonary artery is a rare entity. Aneurysm of the peripheral artery are even less common. An 14-year-old girl was admitted for the evaluation of cardiac murmur. There was a variable grade 2/6 systolic murmur along the left sternal border. The chest x-ray showed a round mass in the right perihilar region. Echocardiogram demonstrated a small muscular ventricular septal defect with mild... |