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Volume 41(12); Dec 1998
Expression of AQP-4 in Developing Rat Stomach : An Immunohistochemical Study
Seung Il Kim
Accepted January 1, 1970  
Purpose : AQP-4 is restricted to basolateral membranes of parietal cells located in the gastric glandular base. Whereas, there is no AQP-4 immunoreactivity in the parietal cells of isthmus/neck region of gastric gland. Expression of AQP-4 in parietal cells might be related with the functional differentiation and maturation of parietal cells. The purpose of this study was to establish the...
Clinical Lecture
Diagnosis and Treatment of Childhood Anemia
Kun Soo Lee
J Korean Pediatr Soc. 1998;41(12):1617-1622.   Published online December 15, 1998
Original Articles
A Clinical Analysis on Acute Lower Respiratory Tract Infections in Children Caused by Influenza Virus in Children
Kiehl Hyung Lee, Woo Kyung Kim, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Kyu Man Lee
J Korean Pediatr Soc. 1998;41(12):1623-1631.   Published online December 15, 1998
Purpose : Although annual epidemics occur, there are only a few clinical studies on influenza in Korea. We evaluated the epidemic and clinical features of acute lower respiratory tract infections in children by influenza virus. Methods : From Feb., 1995 to July, 1997, influenza virus isolations and clinical review were performed on hospitalized children with acute lower respiratory tract infections at...
Effects of Cefodizime on Phagocytosis of COS-1 Ccells
Pyoung Han Hwang, Sang Yun Nam, Ho Keun Yi, Min Ho Kim, Kong Soo Kim, Jung Soo Kim
J Korean Pediatr Soc. 1998;41(12):1632-1638.   Published online December 15, 1998
Purpose : Cefodizime is a new third-generation cephalosporin which has a structure and immunomodutation properties similar to cefotaxime. Various studies on cefodizime have demonstrated the direct eradication of bacteria in cooperation with the host defense mechanism, particularly with phagocytosis. We evaluated the effects of cefodizime on the phagocytosis of COS-1 cells transfected with FcγRI/γγ or FcγRIIA cDNA. Methods : Phagocytosis was...
Cardiovascular Doppler Flow Waveforms in Human Fetuses
Young Mi Hong
J Korean Pediatr Soc. 1998;41(12):1639-1649.   Published online December 15, 1998
Purpose : Doppler echocardiography has been used to identify fetal cardiac anatomy and hemodynamics. It can estimate flow velocity, volume, and cardiac output. The purpose of this study was to look at cardiovascular waveforms in fetus and to see if there were any changes in Doppler parameter with fetal growth. Methods : Blood velocity studies were performed across the mitral, tricuspid,...
Study of a Comparison of Ultrasonography with Radiography to Localize the Umbilical Arterial Catheter
Byoung Min Choi, Young Kwan Park, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1998;41(12):1650-1659.   Published online December 15, 1998
Purpose : This study was performed to observe the utilization of ultrasonography in locating the position of UAC and to compare the position with anatomical landmarks seen on radiography. Methods : Optimal position is when the catheter tip is located between T6-T10 or L3-L5 by anteroposterior radiography(AP-R) and above the diaphragm by cross-table lateral radiography(CTL-R). Ultrasonographic studies used a Hewlett Packard...
Anogenital Index of Normal Children and Its Clinical Significance in Children with Constipation
Kyung Rye Moon
J Korean Pediatr Soc. 1998;41(12):1669-1674.   Published online December 15, 1998
Purpose : The purpose of this study was to find an objective criteria to determine the position of normal anus in Korean children and to evaluate the clinical significance of anterior displacement of anus in children with constipation. Methods : Three hundred and thirty-nine normal children and 24 children with idiopathic constipation represented the basis of this study. The position of the normal anus...
Long-term Follow-up Study of Children with Minimal Change Nephrotic Syndrome
Jung Sue Kim, Hae Il Cheong, Hyun Soon Lee, Yong Choi
J Korean Pediatr Soc. 1998;41(12):1675-1684.   Published online December 15, 1998
Purpose : Most of childhood MCNS has a long disease course with frequent relapses. This study was designed to analyze the long-term clinical course of childhood MCNS, focusing at relapsing pattern, treatment response and complications. Mothods : The medical records of 137 children with biopsy-proven MCNS observed during 1976 ti 1996 were analyzed retrospectively. They were classified as initial responders(111 patients,...
The Effect of Low-Dose Dopamine on the Renal Function of Asphyxiated Neonates
Seung Yeon Nam, Eun Ae Par, Seung Joo Lee
J Korean Pediatr Soc. 1998;41(12):1685-1692.   Published online December 15, 1998
Purpose : Low-dose dopamine(0.5-3μg/kg/min) increases renal blood flow, glomerular filtration rate and natriuresis and has protective and therapeutic effects on oliguric renal failures. Asphyxia is the most common cause of acute renal failure in neonates. But the protective effects of dopamine have never been reported in asphyxiated neonates. So we reported the effects of low-dose dopamine on the renal function...
Longterm Follow-up of Autosomal Recessive Polycystic Kidney Disease
June Huh, Il Soo Ha, Hae Il Cheong, Jeong Kee Seo, Yong Choi
J Korean Pediatr Soc. 1998;41(12):1693-1699.   Published online December 15, 1998
Purpose : This study was aimed to assess the clinical manifestations and courses of autosomal recessive polycystic kidney disease(ARPKD). Methods : The medical records of 10 children diagnosed as infantile or juvenile ARPKD at Seoul National University Children's Hospital between January, 1984 and December, 1996, were reviewed, retrospectively. Results : The average age at diagnosis was 3 8/12 years(4months-7 3/12 years)...
Inhibitory Effects of Actinomycin-D and Pentoxifylline on the Production of IL-1α and TNF-α by Human Cord and Adult Blood Mononuclear Cells
Eun Ae Park, Kyung Hyo Kim, Gyoung Hee Kim
J Korean Pediatr Soc. 1998;41(12):1700-1708.   Published online December 15, 1998
Purpose : An area of intense intrest is assessment of new therapeutic modalities that regulate the inflammatory response in acute bacterial infection is proving to be an area of interest these days. So we conducted this study to compare the inhibitory effects of actinomycin-D and pentoxifylline on the production of IL-lα and TNF-α from cord blood mononuclear cells(MC) to those...
Case Reports
A Case of Intracoronary Collaterals Misinterpreted as Segmental Stenosis in Kawasaki Disease - Descriptive Method of Coronary Arterial Lesions -
Hee-Sun Chung, Young-Yoo Kim, Seung-Il Kim, Jong-Wan Kim, yung-Tai Whang
J Korean Pediatr Soc. 1998;41(12):1709-1716.   Published online December 15, 1998
Visualization of coronary collaterals in coronary arteriography performed in vivo constitutes an important finding, and particularly in the presence of coronary artery disease, it allows observations related to the hemodynamic consequences of the disease process. Undoubtedly, the presence of collateral flow indicates that a compensatory mechanism has developed to ameliorate the detrimental effect of blood flow cessation due to obstruction...
A Case of FGFR2 Exon Ⅲc Mutation in Crouzon Syndrome
Seon Chan Bae, Eun Ha Lee, Moon Sung Park, Si Houn Hah, Chang Ho Hong
J Korean Pediatr Soc. 1998;41(12):1717-1721.   Published online December 15, 1998
Crouzon syndrome, an autosomal dominant disorder, has characteristic features of craniosynostosis, hypertelorism, exophthalmos, maxillary hypoplasia and relative mandibular prognathism. Mutations of fibroblast growth factor receptor 2(FGFR2) gene are associated with craniosynostotic conditions, such as Crouzon syndrome, Jackson-Weiss syndrome, Pfeiffer syndrome, Apert syndrome and Beare-Stevenson cutis gyrata. We found one child with common morphological features of Crouzon syndrome. Interestingly, she...
A Case of VURD Syndrome
Sun Young Kim, Eu Jun Yang, Jae Hong Park, Su Young Kim, Sang Don Lee
J Korean Pediatr Soc. 1998;41(12):1722-1725.   Published online December 15, 1998
VURD syndrome is a disorder characterized by a posterior urethral valve, unilateral reflux, and ipsilateral renal dysplasia. This syndrome is not uncommon, with an incidence in the range of 15 to 20% in patients with posterior urethral valve. Etiology is not clear, but there are a few reports that renal dysplasia is either a result of hydrostatic pressure transmitted to...
A Case of Congenital Factor Ⅶ Deficiency Associated with Intraventricular Hemorrhage and Hydrocephalus
Hyoung Jun Kim, Jin Hwa Jung, Jeong Ho Lee, Jong Dae Jo
J Korean Pediatr Soc. 1998;41(12):1726-1730.   Published online December 15, 1998
Congenital factor Ⅶ deficiency is a rare bleeding disorder with an estimated incidence of 1 in 500,000. It is inherited as an autosomal recessive pattern with variable expression and high penetrance. In severely affected patients, repeated hemarthroses, chronic crippling hemarthropathy, and dangerous hematomas can occur. Other types of hemorrhage include epistaxis, menorrhagia, hematuria, gastrointestinal and gingival bleeding. Fetal cerebral hemorrhage...
A Case of Imported Falciparum Malaria in a Child
J Korean Pediatr Soc. 1998;41(12):1731-1735.   Published online December 15, 1998
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