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Volume 41(9); Sep 1998
Clinical Lecture
Recent Advances in Neonatal Hyperbilirubinemia
Young-Youn Choi
J Korean Pediatr Soc. 1998;41(9):1165-1170.   Published online September 15, 1998
Original Articles
A Study on the Factors Affecting Neonatal Birth Weight
Eun Young Hwang, Soo Beom Hwang, Jin Kil Par, Byung Mann Cho
J Korean Pediatr Soc. 1998;41(9):1171-1179.   Published online September 15, 1998
Purpose : A low birth weight(LBW) rate is associated with perinatal morbidity and mortality. Many different factors are related to birth weight and LBW. This study examined the effects of various factors on birth weight. Methods : The study was conducted from January 1997 to August 1997 through direct interview with mother and medical history. Sample were drawn from 1,248 pairs...
Effect of Dexamethasone on Preventing the Laryngeal Edema Following Extubation in Neonates
Joon Sung Kim, Young Youn Choi, Jae Sook Ma, Tai Ju Hwang
J Korean Pediatr Soc. 1998;41(9):1180-1187.   Published online September 15, 1998
Purpose : We performed this study to evaluate the clinical efficacy and safety of dexamethasone in preventing laryngeal edema following exubation. Methods : We retrospectively reviewed the medical records of 100 neonates who underwent endotracheal intubation and mechanical ventilation. Subjects were divided into two groups; dexamethasone treated(60 cases, dexamethasone group) and non-treated(40 cases, control group). We examined the underlying diseases of...
Prognostic Factors for Mortality in Neonates with Respiratory Distress Syndrome After Surfactant Replacement Therapy
Nam Soo Kang, Byung Min Choi, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1998;41(9):1188-1197.   Published online September 15, 1998
Purpose : To evaluate the association between neonatal mortality and the initial response to surfactant replacement therapy, and to examine the correlation between the response type and other prognostic factors. Methods : Sixty-seven neonates with respiratory distress syndrome(RDS) were divided into two groups; group I(n=51) who survived and group II(n=16) who died within the first 28 days of life after one...
Delayed Cerebral Energy Failure After Acute Hypoxia-Ischemia in Neworn Piglet Under 48hours of Continuous Monitoring Using Near-Infrared Spectroscopy
Yun Sil Chang, Won Soon Park, Munhyang Lee, Ki-Soo Kim, Jung-Hwan Choi, Son Moon Shin
J Korean Pediatr Soc. 1998;41(9):1198-1210.   Published online September 15, 1998
Purpose : To test the hemodynamic and biochemical sequences of secondary cerebral energy failure after acute reversed hypoxic ischemic brain insult(HI) can be reproduced in newborn piglets. Methods : Fifteen anesthetized, ventilated newborn piglet(<3 day) were studied. Eight(HI) were induced transient HI by breathing 8% oxygen and complete occlusion of bilateral common carotid arteries for 30 minutes followed by reoxygenation...
The Effect of Empirical Antibiotics in Febrile Neutropenia
Ju Suk Lee, Young Tak Lim
J Korean Pediatr Soc. 1998;41(9):1209-1215.   Published online September 15, 1998
Purpose : This study was designed to evaluate the safety and efficacy of early cessation of antibiotic treatment regardless of absolute neutrophil count in children with febrile neutropenia and no identifiable infectious source. Methods : A prospective randomized clinical trial was performed in 93 episodes of fever in 37 neutropenic children with cancer, who were admitted to the Department of...
Clinical Manifestations and Hematologic Complications of Epstein-Barr Virus Infection in Korean Children
Seong Hoi Jeon, Chan Wook Woo, Jung Hwa Lee, Kwang Chul Lee, Young Chang Tocko
J Korean Pediatr Soc. 1998;41(9):1216-1223.   Published online September 15, 1998
Purpose : Epstein-Barr virus(EBV) is associated with various diseases and complications caused by the host's immune reactions. This study focuses on various clinical findings and hematologic complications in childhood EBV infection. Methods : The study group was thirty-eight EBV infected children(Anti-EBV VCA IgM; positive) who were admitted to the Department of Pediatrics, Korea University from January 1996 to July 1997. Patients...
Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus
Young Choi, In Seok Lim, Tae Sub Shim, Mi Kyung Lee, Ae Ja Park
J Korean Pediatr Soc. 1998;41(9):1224-1233.   Published online September 15, 1998
Purpose : Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by mecR1 and mecI. Deletion or mutation which occurred in mecI is considered to be associated with constitutive production of PBP 2a. We investigated the distribution of mec regulator genes...
Gastroesophageal Reflux Disease in Children with Chronic Cough
Pan Joo Lim, Jae Ock Park, Dong Hwan Lee, Sang Mann Shin, Dong Won Kim
J Korean Pediatr Soc. 1998;41(9):1234-1242.   Published online September 15, 1998
Purpose : We investigated the incidence of gastroesophageal reflux disease(GERD) by 24-hour esophageal pH monitoring in patients who had chronic cough for more than 3 weeks. Methods : From January 1995 to August 1996, 33 patients with chronic cough which had lasted for more than 3 weeks were enrolled in the 24-hour esophageal pH monitoring. The result was interpreted with the...
Prevalence and Clinical Features of Wolff-Parkinson-White(WPW)- Type Ventricular Preexcitation Syndrome in Children
Byung Ju Kim, Jae Sook Ma
J Korean Pediatr Soc. 1998;41(9):1243-1249.   Published online September 15, 1998
Purpose : This study was conducted to establish the prevalence and clinical features of WPW- type ventricular preexcitation syndrome in children. Methods : Eighteen patients were discovered by the mass heart disease screening using ECG on 47,691 elementary school children in Kwangju from September 1992 to December 1994(group 1), and 14 patients were diagnosed at the Department of Pediatrics, Chonnam...
Thyroid Function Studies in Patients Who Underwent Open Heart Surgery
Hyung Joo Sohn, Yu In Park, Chang Sung Son, Joo Won Lee, Young Chang Tockg
J Korean Pediatr Soc. 1998;41(9):1250-1255.   Published online September 15, 1998
Purpose : Alteration in the serum level of thyroid hormone can occur following open heart surgery due to major stress and hemodilution after extracorporeal circulation but these changes have been ignored. The purpose of this study is to evaluate the changes of thyroid hormone level after open heart surgery and if these changes influence the prognosis. Methods : We evaluated 26...
Short Term Effect of Recombinant Human Growth Hormone Therapy in Children with Chronic Renal Failure
Si-Whan Ko, Dong-Kyu Ji
J Korean Pediatr Soc. 1998;41(9):1256-1261.   Published online September 15, 1998
Purpose : Growth retardation is one of the major side effects of chronic renal failure. In this study, the short-term growth promoting effect, effect on the chemical parameters, and probable side effects of growth hormone treatment to child patients with chronic renal failure were examined. Methods : The research sample was 5 child patients diagnosed with chronic renal failure and receiving...
The Clinical Significance of Serum Sodium Concentration in Febrile Convulsion
So Young Park, Seung Joo Lee
J Korean Pediatr Soc. 1998;41(9):1262-1267.   Published online September 15, 1998
Purpose : Recently hyponatremia was reported to be common in febrile convulsion and related to the probability of a repeated convulsion. It was documented that hyponatremia lowers the threshold for convulsion in experiment animals. We therefore studied the relationship between hyponatremia and febrile convulsion. Methods : Serum sodium concentration was measured in 82 children with febrile convulsions and 66 age-matched febrile...
Thymopentin Therapy in Atopic Dermatitis
Geun Woong Noh, Ki Young Lee
J Korean Pediatr Soc. 1998;41(9):1268-1272.   Published online September 15, 1998
Purpose : Atopic dermatitis is a chronic relapsing inflammatory skin disease that results from allergic reaction. Steroid therapy has become a major therapeutic modality for treatment of atopic dermatitis. Several immunomodulatory therapies have been tried for atopic dermatitis. In this study thymopentin therapy was performed and its clinical effects and laboratory results were evaluated. Methods : Atopic dermatitis with typical clinical...
The Significance of Family History, Immunoglobulin E, Total Eosinophils and Eosinophil Cationic Protein as a Predictor of Allergic Diseases
Dong Su Park, Hyun Hee Kim, Joon Sung Lee
J Korean Pediatr Soc. 1998;41(9):1273-1282.   Published online September 15, 1998
Purpose : Family history of allergy and cord blood immunoglobulin E concentration have been proven to be predictors of the development of allergic diseases in children. The purpose of this study is to evaluate whether maternal, cord and baby's blood total eosinophils or eosinophil cationic protein(ECP) in addition to the above two predictors could be a predictor of subsequent allergic...
Case Reports
A Case of Congenital Tuberculosis Misdiagnosed as Fungal Pneumonia
Hye Kyung Lee, Young Chang Kim, Young Tong Kim
J Korean Pediatr Soc. 1998;41(9):1283-1287.   Published online September 15, 1998
A Case of Nutcracker Esophagus Combined with Hypertensive Lower Esophageal Sphincter
Seong-Hun Kim, Ju-Suk Lee, Su-Eun Park, Sang-Ook Na, Jae-Hong Park
J Korean Pediatr Soc. 1998;41(9):1288-1292.   Published online September 15, 1998
Nutcracker esophagus and hypertensive lower esophageal sphincter(LES) are primary esophageal motility disorders. Nutcracker esophagus have demonstrated distal esophageal contraction amplitude that exceeds the normal range(>160mmHg), without association abnormalities of the esophageal contraction wave, or lower esophageal sphinter relaxation. The criteria for diagnosing hypertensive LES take the mean LES pressure >45mmHg, LES relaxation >75% and normal peristalsis, which is a poorly...
A Case of Congenital Intestinal Lymphangiectasia
Pan Joo Lim, Jae Ock Park, Dong Hwan Lee, Sang Mann Shin, Dong Won Ki
J Korean Pediatr Soc. 1998;41(9):1293-1298.   Published online September 15, 1998
Intestinal lymphangiectasia is a primary or secondary disorder of lymphatics which is associated with protein-losing enteropathy, hypoalbuminemia, edema, abdominal distension and growth failure. The patients with this disease lose albumin, immunoglobulins, and lymphocytes through the bowel. We have experienced one case of intestinal lymphangiectasia in 8 month-old boy, whose chief complaint was abdominal distension and watery diarrhea. He had hypoalbuminemia(1.7gm/dl)....
A Case of Polyglandular Autoimmune Syndrome
Kyung Ah Choi, Ji Yeoun Kang, Chul Hoe Koo, Wha Mo Lee, Young Suk Jeon
J Korean Pediatr Soc. 1998;41(9):1299-1303.   Published online September 15, 1998
When dysfunction of two or more endocrine glands occurs in association with circulating organ specific antibodies directed against the involved glands, the term polyglandular autoimmune(PGA) syndrome is applied. This syndrome is usually classified into three groups. The autoimmune nature of this disease has been based on the presence of lymphocytic infiltration of the affected glands, organ specific autoantibody in serum,...
A Case of Septic Pulmonary Embolism in Neonate
Sang Hee Lee, In Hoon Lee, Jin Kuk Kim, Byung Do Nam, Ju Seok Lee, Jae Hong Park
J Korean Pediatr Soc. 1998;41(9):1304-1308.   Published online September 15, 1998
Septic pulmonary embolization is an uncommon condition in which the clot or fibrin matrix, contaminated with micro-organisms, lodge in the pulmonary arterial tree, leading to infarction, suppuration and other complications. The septic emboli reach the lung from a variety of sources, including acute suppurative pelvic thrombophlebitis, infective endocarditis involving tricuspid and pulmonary valve, osteomyelitis, suppurative lesions of the neck, infected...
Opinion regarding RT 23 PPD 2TU: The committee on infectious disease, Korean Pediatrics Society.
J Korean Pediatr Soc. 1998;41(9):1309.   Published online September 15, 1998
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