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Volume 42(2); Feb 1999
Clinical Lecture
Cardiac Murmurs : Differential Diagnosis of Innocent and Pathologic Murmurs
Chang Sung Son
J Korean Pediatr Soc. 1999;42(2):157-163.   Published online February 15, 1999
Original Articles
Clinical Effect and Complication of High Frequency Ventilation on Respiratory Failure
Man Hoe Hur, Yong Gook Kim, Ji Yun Baek, Sang Geel Lee
J Korean Pediatr Soc. 1999;42(2):164-172.   Published online February 15, 1999
Purpose : Flow interruptor high frequency ventilator(HFV) on neonatal respiratory failure caused by various disorders has been applied in order to assess its therapeutic effect and safety. Methods : Premature babies below 1.8kg with respiratory failure from 1991 to 1997 in the Fatima neonatal intensive care unit(NICU) for 6 year and 4 months are included. Flow interruptor HFV with low...
Significance of Polymerase Chain Reaction Test for Diagnosis of Mycoplasma pneumoniae Pneumonia
Hae-kyung Lim, Young-Hun Chung
J Korean Pediatr Soc. 1999;42(2):173-179.   Published online February 15, 1999
Purpose : Mycoplasma pneumoniae is a common cause of lower respiratory disease, especially in children and young adults. The diagnosis, in most cases, is confirmed by serology. M. pneumoniae is difficult to culture because of its fastidious nature, and growth is too slow for diagnostic use. In this prospective study, the sensitivity and specificity of the PCR assay was evaluated...
A Seroepidemiologic Study on Hepatitis A in Seoul, Korea
Dong Woon Yang, Young Ah Lee, Jung Yeon Shim, Jin Young Park, Hye Lim Jung, Moon Soo Park, Dong Hyeuk Keum
J Korean Pediatr Soc. 1999;42(2):180-185.   Published online February 15, 1999
Purpose : The prevalence of hepatitis A(HAV) in a certain community reflects that community’s living standard and hygienic condition. And the pattern of HAV infection differs over time and geography, with varying widely from country to country and even within the same city. Recently a shift in prevalence has been observed in cases from childhood to adulthood. We studied HAV...
Clinical Characteristics of Long-Standing Foreign Body in Airway
Jin Hwa Jeong, Seon Mi Jin, Yun Ae Jeon, Ki Woong Sung, Young Yull Koh
J Korean Pediatr Soc. 1999;42(2):186-194.   Published online February 15, 1999
Purpose : Although the diagnosis of foreign bodies in the airway can be made early, retained and neglected foreign bodies are a common occurrence. The objective of this study was to characterize the clinical features of children diagnosed beyond 14 days following inhalation of a foreign body, long-standing foreign body in airway(LFB). Methods : We reviewed the records of 180 cases...
Clinical Efficiency of Cardiac Troponin T for Myocardial Damage in Neonatal Asphyxia
Nam Soo Kang, Jae Kyun Yoon, Chang Sung Son, Joo Won Lee, Young Chang Tokgo, Sang Hee Kim
J Korean Pediatr Soc. 1999;42(2):195-202.   Published online February 15, 1999
Purpose : The aim of this study was to evaluate the clinical efficiency of cardiac troponin T (cTnT) in detecting myocardial damage in neonatal asphyxia and to compare the diagnostic value of cTnT with creatine kinase MB(CK-MB). Methods : Sixty-three neonates were enrolled in this study, consisting of 27 asphyxiated infants (asphyxiated group; 1-min or 5-min Apgar score≤6) and 36 healthy...
Estimating Fetal Cardiac Output by Doppler Echocardiography
Young Mi Hong
J Korean Pediatr Soc. 1999;42(2):203-210.   Published online February 15, 1999
Purpose : Doppler echocardiography has been used to identify fetal cardiac anatomy and hemodynamics. It can estimate flow velocity, volume, and cardiac output. The purposes of this study were to estimate right and left ventricular stroke volume and cardiac output in fetus, and to see if there were any changes of right and left ventricular parameter with fetal growth. Methods :...
Assessment of Myocardial Ischemia using Myocardial Perfusion Scan in Kawasaki Disease
Hong Ryang Gil, Jung Yun Choi, Myeong Ja Yoon, Soon Seong Park, Ho Sung Kim, Chung Il No, Yong Soo Yoon, Myung Chul Lee, Dong Soo Lee
J Korean Pediatr Soc. 1999;42(2):211-220.   Published online February 15, 1999
Purpose : Myocardial scintigraphy has been reported to be useful in adults, but its usefulness in children is limited. This study was done to determine the feasibility and accuracy of 99mTc-MIBI SPECT(sestamibi, methoxy-isobutyl-isonitrarite myocardial single emission computed tomography, Dp-SPECT) after dipyridamole infusion to detect coronary obstructive lesions in Kawasaki disease (KD). Methods : Dp-SPECT was performed in 21 control(group 1), 8...
Predictive Factors of Saline Reduction under Ultrasound-guidance in Patients with Intussusception
Jung-Hye Min, Hye-Young Lee, Eun-Sun Yo, Jeong-Wan Seo, Seung-Joo Lee, Sun-Hwa Lee
J Korean Pediatr Soc. 1999;42(2):221-226.   Published online February 15, 1999
Purpose : The purpose of this study was to investigate the predictive factors of saline reduction under ultrasound-guidance in patients with intussusception. Methods : Ultrasound-guided saline enema reductions were performed in 105 patients with intussusception from September 1993 to April 1996 at Ewha Womans University Mok-dong Hospital. Clinical characteristics and ultrasonographic findings were analyzed as the predictive factors of ultrasound-guided saline...
Clinical Study of Post-Traumatic Seizure in Childhood and Adolescence
Jang Weon Moon, Soo Ahn Chae, Dong Keun Lee
J Korean Pediatr Soc. 1999;42(2):227-232.   Published online February 15, 1999
Purpose : As morbidity and mortality resulting from physical trauma have significantly increased, the importance of trauma concerning medical, legal, and socioeconomic issues has been widely documented. Studies of post-traumatic seizure after head trauma have been reported, but mostly in adults. So this study was performed to analyse clinical findings on head trauma patients under 20 years of age. Methods :...
A Clinical Study on Infantile Spasms with Vigabatrin Therapy
Seung Jung Oh, Sung Gun Park, Hyun Ho Kang, Sa Jun Chung
J Korean Pediatr Soc. 1999;42(2):233-238.   Published online February 15, 1999
Purpose : Infantile spasms are considered an age-specific and malignant epilepsy. It is not controlled easily by general anticonvulsants. Therefore, this study aimed to assess vigabatrin(VGT) efficacy in infantile spasms. Methods : From January 1992 to December 1995, 35 children with infantile spasms, who were diagnosed at Kyung Hee University Hospital and treated vigabatrin, were analyzed retrospectively. Results : The ratio of...
Distribution and Expression of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid(AMPA) Receptor Subunits in Moderate Hypoxic Newborn Piglet Brain
Na Yeon Kim, Woo Taek Ki
J Korean Pediatr Soc. 1999;42(2):239-248.   Published online February 15, 1999
Purpose : The mechanism of hypoxic damage is mainly intracellular influx of calcium ions through the glutamate ionotropic receptor(NMDA, AMPA/kainate). This study was performed to determine alterations in distribution and expression of AMPA receptor subunits after 1-hour of moderate hypoxia in the newborn piglet brain, in a state of mild to moderate perinatal hypoxic-ischemic encephalopathy. Methods : Ten newborn piglets were...
Clinical Study of Status Epilepticus in Children
So Young Lee, Seung Hee Jung, Yong Kuk Kim, Byung Hak Lim
J Korean Pediatr Soc. 1999;42(2):249-256.   Published online February 15, 1999
Purpose : Convulsive status epilepticus(SE) is a serious, life-threatening neurological condition that requires immediate treatment to avoid significant morbidity and mortality. Despite improvements in the diagnosis and treatment of SE in the last two decades, SE in young infancy is still associated with high morbidity and mortality. Thus, understanding the varied etiology and clinical presentation and prognosis of SE is...
Diagnostic Utility of D-dimer Test in Disseminated Intravascular Coagulation with Sepsis
Jung Eun Kim, Young Mi Hong, Gyung Hee Kim
J Korean Pediatr Soc. 1999;42(2):257-263.   Published online February 15, 1999
Purpose : Disseminated intravascular coagulation(DIC) is a confusing disorder from both a diagnostic and therapeutic standpoint. In order to investigate the effectiveness of D-dimer test in disseminated intravascular coagulation associated with sepsis, D-dimer level and other laboratory tests were performed. Methods : Fifty patients with disseminated intravascular coagulation associated with sepsis, who were admitted to the department of pediatrics, were evaluated by...
Case Reports
A Case of Pure Red Cell Anemia Complicated by Antiepileptic Drugs
Hyunmi Kim, Sang Gyu Park, Sung Ryeul Kim
J Korean Pediatr Soc. 1999;42(2):264-267.   Published online February 15, 1999
A 12-year-old boy developed pure red cell anemia(PRCA) during a combination therapy of antiepileptic drugs(AEDs) for epilepsy. His complex partial seizure was intractable to monotherapy. During 7 months of treatment, he was treated with Vigabatrin, Carbamazepine and Valproate. While switching from Carbamazepine to Valproate, he presented anemia but with no jaundice. His hemoglobin was 4.1g/dl bone-marrow biopsy revealed erythroid hypoplasia...
A Case of Type Ⅱ Ehlers-Danlos Syndrome
Dong Hwan Oh, Jin Kuk Kim, Beuyng Do Nam, Ju Eun Lee, Je Hong Park
J Korean Pediatr Soc. 1999;42(2):268-273.   Published online February 15, 1999
Ehlers-Danlos syndrome represents a group of inherited connective tissue disorders characterized by varying degrees of joint laxity, skin fragility and hyperextensibility, and a bleeding tendency. The essential defect is a quantitative deficiency of collagen. At present, 10 clinical forms have been recognized on the basis of extent and severity of the principal features, in combination with other abnormalities and the...
A Case of Microscopic Polyangitis Presented as Pulmonary Hemorrhage and Rapidly Progressive Glomerulonephritis
Jae Eun Lee, Young Sook Chae, Oh Keyng Lee, Dae Youl Lee
J Korean Pediatr Soc. 1999;42(2):274-278.   Published online February 15, 1999
Microscopic polyangitis(MPA) is defined as a systemic necrotizing vasculitis that affects small- sized vessels without granulomata. MPA is associated with focal segmental necrotizing glomerulonephritis. Clinical manifestations are similar to those of polyarteritis nodosa, but are characterized by the presence of rapidly progressive glomerulonephritis and pulmonary involvement, including pulmonary hemorrhage. We reported a case of microscopic polyangitis presenting pulmonary hemorrhage and...
A Case of Septic Pulmonary Emboli in Ventricular Septal Defect
Keum Bong Jee, Jae Kook Cha, Kon Hee Lee, Kwan Seop Lee
J Korean Pediatr Soc. 1999;42(2):279-283.   Published online February 15, 1999
Septic pulmonary emboli(SPE) is derived from a variety of sources, including infected heart valves, peripheral sites of septic thrombophlebitis and infected venous catheters or pacemaker wires. In adult intravenous drug users, the most common cause of septic emboli is tricuspid valve endocarditis, but infective endocarditis in the non-complicated ventricular septal defect is a relatively rare condition in infants and...
A Case of Allergic Bronchopulmonary Aspergillosis During Childhood
Kyoung Ah Ha, Chang Keun Kim, Churl Young Chung, Jung Sook Kim
J Korean Pediatr Soc. 1999;42(2):284-288.   Published online February 15, 1999
Allergic bronchopulmonary aspergillosis(ABPA) is an inflammatory disease which causes a hypersensitivity to Aspergillus spores growing in the bronchi. The clinical syndrome is characterized by asthma, recurrent pulmonary infiltrations or mucoid impaction, eosinophilia, and central bronchiectasis. A 12-year-old boy was admitted to our hospital because of right lower chest pain and cystic mass-like shadows on a chest X-ray film. He had...
A Case of Ulcerative Colitis with Growth Disturbance
Ki Hyun Jeon, Dong Hyun Choi, Eun Yung Seol, Kyung Eun Oh, Mun Ki Cho, Chul Son, Jong Soon Kim
J Korean Pediatr Soc. 1999;42(2):289-295.   Published online February 15, 1999
Ulcerative colitis is a chronic relapsing inflammatory disease of the colonic and rectal mucosa, which affects children as well as adults. Inflammation caused by ulcerative colitis is limited to the colon and rectum, to the mucosa and submucosa, and is involved continuously, with varying degrees of ulceration, hemorrhage, edema, and regenerating epithelium. Ulcerative colitis most commonly presents with the onset...
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