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Volume 43(10); Oct 2000
Clinical Lecture
Pediatric Urologic Diseases
Jin Il Kim
J Korean Pediatr Soc. 2000;43(10):1303-1310.   Published online October 15, 2000
Original Articles
Organic Acid Analysis on Urine Samples Obtaine3d from Dried Filter Paper in Newborns : Development of Screening Method for Organic Aciduria in Newborns
Eun Ha Lee, Si Houn Hahn
J Korean Pediatr Soc. 2000;43(10):1311-1317.   Published online October 15, 2000
Purpose : Neonatal screening for inherited metabolic disease is aimed at identifying affected infants early, thus permitting medical intervention to prevent or minimize the effect of the disease. However, organic aciduria, most of which causes severe disease and mental retardation, is not yet screened routinely because of the difficulty of tests, sample collection, and expenditure of time and financial resources....
Effects of Ductal Closure on Flow Velocities of Peripheral Pulmonary Arteries in Normal Term Infants
Hae-Soon Kim, Se Jeong Sohn, Young Mi Hong
J Korean Pediatr Soc. 2000;43(10):1318-1322.   Published online October 15, 2000
Purpose : This study was performed to evaluate whether a relationship may exist between transient peripheral pulmonary stenosis and the closure of the ductus arteriosus in term infants. Methods : A total of 69 healthy full-term infants had pulmonary artery and ductal color Doppler flow velocity assessment performed at of 10 hours age(group I), 1-2 days of age(group II), and...
Epidemiologic Characteristics of T Serotyping in Relation to the Outbreak of Erythromycin Resistant Streptococcus pyogenes
Sung-Ho Cha, Kyu Jam Hwang, Young Hee Lee
J Korean Pediatr Soc. 2000;43(10):1323-1329.   Published online October 15, 2000
Purpose : The identification of antigenic specificity of Streptococcus pyogenes using T serotyping is important to understand biologic characteristics of microorganisms. We would like to disover the association of the occurrence of predominant T type, with possible outbreak of erythromycin resistant Streptococcus pyogenes in this country, which has been documented since the late 1990s. Methods : Throat swab cultures were taken...
Molecular Epidemiologic Study of Streptococcus pyogenes Analyzed by T protein Serotyping and Pulsed Field Gel Electrophoresis(PFGE) in Normal Children
Jin Ah Son, Don Hee Ahn, Kyu Jam Hwang, Younghee Lee, Sung-Ho Cha
J Korean Pediatr Soc. 2000;43(10):1330-1342.   Published online October 15, 2000
Purpose : In this study we tried to look at the spreading, duration of colonization, and acquisition of new streptococci which were obtained in one geographical area, as well as the bacteriologic and molecular epidemiology of normal school children carrying group A streptococci and their clonal relationship through the combined application of the serotype of T antigen and Pulsed Field...
Early Results of Stent Implantation in Branch Pulmonary Artery Stenosis after Tetralogy of Fallot Repair
Sung Kyu Lee, Sang Hun Lee, Jae Young Lee, Su Jin Kim, Mi Young Han, Do Jun Cho, In Seung Park, Eun Jung Bae, Sung Ho Kim
J Korean Pediatr Soc. 2000;43(10):1343-1349.   Published online October 15, 2000
Purpose : Pulmonary artery stenosis is mainly complicated by aortopulmonary shunt or total correction of tetralogy of Fallot(TOF). Results of surgical angioplasty are poor and the success rate of balloon angioplasty is 53-72%. Endovascular stents have been applied to these lesions. The purpose of this study is to evaluate the early results of stent implantation in postoperative pulmonary artery stenosis...
Changes of Peripheral IFN-γ-Producing CD4(+) and CD4(-) Cell Frequencies in Kawasaki Disease
Joung-Min Eom, Heon-Seok Han, Youn-Soo Hahn
J Korean Pediatr Soc. 2000;43(10):1350-1355.   Published online October 15, 2000
Purpose : This study was performed to analyze the frequencies of peripheral IFN-γ-producing cells at the single cell level, and to determine concentrations of circulating interferon-γ(IFN-γ) in the acute and subacute phases of Kawasaki disease(KD). Methods : Ten patients with KD were studied and seven healthy children were selected as control subjects. Using immunofluorescent detection of intracellular IFN-γ in CD4(+) and...
The Role of Nitric Oxide in Seizures Induced by Pentylenetetrazole
Jun Ho Kim, Doo Kwun Kim
J Korean Pediatr Soc. 2000;43(10):1356-1363.   Published online October 15, 2000
Purpose : Nitric oxide(NO) is a highly reactive messenger molecule that is synthesized by nitric oxide synthase(NOS) in a number of tissues including the brain. Our aim was to examine the possible role of NO on pentylenetetrazole(PTZ)-induced seizure in rats as a proconvulsant or an anticonvulsant. Methods : Male Sprague-Dawley rats weighing 200-300g were used. PTZ(40mg/kg) was used to induce seizure....
Detection Limit of Minimal Residual Disease in Leukemia Using Fluorescence in situ Hybridization
Jung Hyun Lee, So Young Kim, Hyun Hee Kim, Byung Kyu Suh, Wonbae Lee, Kyung Tai Whang
J Korean Pediatr Soc. 2000;43(10):1364-1371.   Published online October 15, 2000
Purpose : The close relationship between the size of a tumor burden and the curability of acute leukemia is well established. Therefore, it is very important to detect residual leukemia accurately at low levels. Fluorescence in situ hybridization(FISH) techniques rely on chromosome-specific and gene specific DNA probes to identify numerical and structural chromosomal abnormalities. But the detection limit of FISH...
Study on the Interrelationship of Air Pollution and Respiratory Diseases in Inchon City Via Children Who Visited the Emergency Room of Inha University Hospital
Hyun Choi, Dae Hyun Lim, Jung Hee Kim, Byong Kwan Son, Jong Whan Lim, Youn Chol Hong
J Korean Pediatr Soc. 2000;43(10):1372-1379.   Published online October 15, 2000
Purpose : It is generally accepted that air pollution can cause acute respiratory diseases. This study assessed the relationship between air pollution and development of pediatric respiratory diseases in Inchon city. Methods : We studied a number of pediatric patients who developed respiratory diseases such as bronchial asthma, bronchiolitis, URI, bronchitis and pneumonia and visited the Inha University Hospital emergency room...
Effectiveness of Polaroid Photoscreening for Amblyogenic Fctors in Infants & Young Children
Su Mi Ihn, Sang Hyun Byun, Hang Jin Cho, Byung Mu Min
J Korean Pediatr Soc. 2000;43(10):1380-1385.   Published online October 15, 2000
Purpose : Amblyopia is the commonest cause of defective vision in childhood. It develops during the sensitive period of visual maturation which continues until about 7-8 years of age. The authors investigated the effect of a polaroid photoscreening camera designed to detect amblyogenic factors, including asymmetric and abnormal refractive errors, strabismus, ptosis and media opacities. Methods : Fifty-four children aged...
Case Reports
A Case of Omphalocele-Exstrophy-Imperforate Anus-Spina Bifida(OEIS syndrome)
Hyeon Jong Yang, Lae Kyung Park, Han Jin Kim, Hye Kyung Lee, Young Chang Kim
J Korean Pediatr Soc. 2000;43(10):1386-1389.   Published online October 15, 2000
Omphalocele-exstrophy-imperforate anus-spinal defects(OEIS Syndrome) is a single defect in early mesoderm, and its incidence is about one in 250,000. If was first described by Littre in 1709. The characteristics of this disorder is omphalocele, extrpohy of bladder, imperforate anus and spina bifida. There have been reports of longtime survival made possible by several operations, but for most cases normal life...
A Case of Ventricular Tachycardia after Chloral Hydrate Ingestion
Hye Kyung Lee, Yoon Seop Jeong
J Korean Pediatr Soc. 2000;43(10):1390-1394.   Published online October 15, 2000
Chloral hydrate is widely used as a sedative or hypnotic, especially in pediatric patients, but cardiac arrhythmia following chloral hydrate administration has rarely been reported in literature up to date. The most common cardiac arrhythmia is ventricular extrasystole. We describe a 17- year-old Down syndrome patient who developed a life-threatening cardiac arrhythmia developed after chloral hydrate administration of 100mg/kg body...
A Case Successfully Treated by Local Low-dose Urokinase Infusion in Neonate with Blalock-Taussig Shunt Partially Occluded by Thrombus
Yong Chan Park, Hyoung Doo Lee, Gyu Tae No
J Korean Pediatr Soc. 2000;43(10):1395-1398.   Published online October 15, 2000
For some cyanotic children with deficient pulmonary blood flow, the Blalock-Taussig shunt is a life-saving or temporizing form of palliation. Extensive experience has been gathered, and mortality and morbidity as well as the incidence of shunt stenosis and thrombosis have significantly decreased. However, even nowadays, the most frequently encountered complication excluding mortality in early postoperative course is occlusion of the...
Three Cases of Hemolysis After Transcatheter Closure of A Patent Ductus Arteriosus
Sang-Bum Lee, Myung Chul Hyun
J Korean Pediatr Soc. 2000;43(10):1399-1403.   Published online October 15, 2000
Severe hemolysis occurred after transcatheter occlusion of a patent ductus arteriosus in 3 patients among 41 patients who underwent transcatheter occlusion of a patent ductus arteriosus. The problems were managed by a standard surgical ligation of the duct, leaving the occlusion device(the Rashkind umbrella and a detachable coil) in situ in one patient, surgical removal of the detachable coil and...
A Case of Pericentric Inversion of Chromosome 5(p15.1q11.2)
Sun Ju Lee, Jin Hwa Jeong, Sung Min Cho
J Korean Pediatr Soc. 2000;43(10):1404-1408.   Published online October 15, 2000
Pericentric inversion of chromosome 5 is a rare chromosomal aberration, which has familial inheritance in a few cases. Many reports demonstrated that the phenotype is similar to the cri-du- chat syndrome. There are many problems regarding the clinical significance for genetic counseling and parental diagnosis. The authors encountered a male neonate who presented clinodactyly, campylodactyly, closed fists with 4th and...
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