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Volume 43(12); Dec 2000
Clinical Lecture
Guideline on the Indication and Timing of Operations
Kwi-Won Park
J Korean Pediatr Soc. 2000;43(12):1533-1535.   Published online December 15, 2000
Original Articles
22q11 Microdeletion and Clinico-Genetic Correlation in CATCH 22 Syndrome
Hong Ryang Kil, Young Ha Lee, Yong Hun Chung, Yong Hun Chung
J Korean Pediatr Soc. 2000;43(12):1536-1544.   Published online December 15, 2000
Purpose : Deletion of chromosome 22q11 is associated with DiGeorge syndrome, velocardiofacial syndrome, and conotruncal anomaly face syndrome. This study was performed to determine the criteria of clinical phenotype as recognizable syndrome and to research the loss of heterozygosity in CATCH 22 patients and their family. Methods : An evaluation of the clinical and genetic profiles of 30 persons of CATCH...
A Study on the Effect of the Combined Use of Gentle Ventilation and High-Frequency Ventilation on the Incidence of Chronic Lung Disease
Ji Yeon Baek, Jae Han Kim, Kyung Ae Park, Suk Ho Kang, Man Hoe Hur, Sang Geel Lee
J Korean Pediatr Soc. 2000;43(12):1544-1551.   Published online December 15, 2000
Purpose : This study was conducted to determine the correlation between the incidence of chronic lung disease and the combined use of gentle ventilation and high-frequency ventilation. Methods : The subject group consisted of 63 very low birthweight infants of less than 1500gm who were born and survived through ventilator treatment in the Fatima neonatal intensive care unit for four...
Effect of Granulocyte-macrophage Colony-stimulating Factor in Neonatal Infection
Il-Young Jo, Sang-Hyun Byun
J Korean Pediatr Soc. 2000;43(12):1552-1557.   Published online December 15, 2000
Purpose : Neutrophils are central to the defences against bacterial infection, and in neonates the number of neutrophils are decreased due to inhibited production and phagocytic function. This induces high mortality rates in infants suffering from neonatal sepsis. Exogenous GM-CSF can increase the number of neutrophils and improve the phagocytic function. To establish the most cost effective dose of exogenous...
Etiology and Clinical Features of Severe Acute Viral Lower Respiratory Tract Infections in Children
Noo Lee Jeon, Bong Seong Kim, Yoo Kyum Kim, Soo-Jong Hong
J Korean Pediatr Soc. 2000;43(12):1558-1568.   Published online December 15, 2000
Purpose : The purpose of the study is to understand the etiology and clinical features of severe acute viral lower respiratory tract infection(LRI), especially in conjunction with the use of ventilator care and/or with bronchiolitis obliterans. Methods : Etiologic agents and clinical features of severe acute viral LRI were studied from July 1998 through June 1999 in children at Asan Medical...
Changes in Incidence of Infantile Transient Methemoglobinemia Associated with Infectious Diarrhea during 1989-1999 in Kyungnam Province
Young Suk Kim, Eun-A Kim, Jae-Young Lim, Myoung-Bum Choi, Chan-Hoo Park, Hyang-Ok Woo, Byung-Kiu Park, Hee-Shang Youn, Yang-Suk Jung, Dong-Jin Lee, Jung Hee Kim, Eun Jeong Kim, Chul Kyu Kim
J Korean Pediatr Soc. 2000;43(12):1569-1576.   Published online December 15, 2000
Purpose : Infantile transient methemoglobinemia(ITM) may develop in association with infectious diarrhea without exposure to any toxic oxidizing agents. We observed that the number of ITM associated with infectious diarrhea have increased at the Gyeongsang National University Hospital (GNUH), located in the western area of Kyungnam province during the last 4 years. To determine whether this phenomenon was similarily observed...
The Changes of Apoptosis and Viability in Stem Cells after Thawing with Lapse of the Time
Seun Joo Park, Sang Young Bae, Kyung Ha Ryu, Il Tae Whang, Kyung Hyo Kim, Young Mi Hong, Kyung Hee Kim, Keun Lee, Joo Young Seoh
J Korean Pediatr Soc. 2000;43(12):1576-1582.   Published online December 15, 2000
Purpose : Thawed stem cells should be infused as early as possible because delay of infusion leads to decrease of cell viability and formation of DNA clumping. The procedure of 10% Dimethyl sulfoxide(DMSO) removal and a long distance from the thawing location to the patient are the main causes of delay of infusion that results in the loss of cell...
High-Resolution Computed Tomography(HRCT) Findings of the Lung in Asthmatic Children and Their Correlation with Clinical Characteristics
Do Kyun Kim, Yang Park, Young Yull Koh, Jung Eun Chun, Woo Sun Kim
J Korean Pediatr Soc. 2000;43(12):1583-1590.   Published online December 15, 2000
Purpose : The purposes of this study were to determine the abnormal high-resolution computed tomography(HRCT) findings of the lung in uncomplicated asthmatic children, to compare the clinical characteristics between normal and abnormal HRCT finding groups and to correlate abnormal HRCT findings with clinical characteristics, especially FEV1 and PC20. Methods : Forty asthmatic children were studied. Inspiratory and expiratory HRCT scans were...
The Clinical Types and Characteristics of Diabetes Mellitus in Korean Children
Eun Gyong Yoo, Hye Jung Shin, Duk Hi Kim
J Korean Pediatr Soc. 2000;43(12):1591-1598.   Published online December 15, 2000
Purpose : Diabetic children should be classified into type 1 or 2 for adequate diabetic control. However, there is a shortage of information of the appropriate criteria in Korea. This study is desinged to discover the clinical types and characteristics of diabetes mellitus(DM) in Korean children. Methods : We studied the clinical characteristics and laboratory findings of 177 diabetic children. Classification...
Case Reports
Identification of a Novel Mutation of Bruton`s Tyrosine Kinase(BTK) Gene in a X-linked Agammaglobulinemia(XLA) Family
Young-Jong Baek, Jae-Ho Lee, Jung-Soo Kim, Chang-Hwa Song, Jeong-Kyu Park, Hwa-Jung Kim, Eun-Kyeong Jo
J Korean Pediatr Soc. 2000;43(12):1599-1607.   Published online December 15, 2000
X-linked agammaglobulinemia(XLA) is a heritable humoral immunodeficiency disease characterized by inefficient expansion of pre-B cells into later B cell stages or incomplete differentiation of B cell precursors to pre-B cells. The gene mutated in XLA was identified as a cytoplasmic tyrosine kinase, named Bruton`s tyrosine kinase(BTK). In this report we investigated the characteristics of immune cells, the patterns of intracellular...
A Case of Ramsay-Hunt Syndrome
Ok Ja Jeong, Se Wook Oh, Se Chang Ham, Yong Won Park
J Korean Pediatr Soc. 2000;43(12):1608-1612.   Published online December 15, 2000
Ramsay Hunt Syndrome was initially described by Ramsay Hunt in 1907 as herpes zoster of the geniculate ganglion. The frequency of RHS in patients with herpes zoster has been calculated to be about 1%. RHS affects mostly adults; however a small number of children with herpes zoster oticus have been reported. We describe a case of RHS in a healthy...
Two Cases of Congenital Paraesophageal Hiatal Hernia in Infancy
Ji Yeon Hong, Kih Yeon Song, Woo Ki Lee, Kwang Woo Kim, Jong Gon Ha, Soon Ok Choi
J Korean Pediatr Soc. 2000;43(12):1613-1620.   Published online December 15, 2000
Herniation of the stomach through the esophageal hiatus into the posterior mediastinum is a commom affliction of humans. The incidence of hiatal hernia is difficult to determine because of the absence of symptoms in a large number of patients. Hiatal hernias are classified into two major types; type I sliding hiatal hernia and type II paraesophageal hiatal hernia. Sliding hernia...
A Case of Congenital Epulis of the Newborn
Dong Gon Lee, Eun Young Kim, Sang Kee Park, eong Ryoul Yang, Dong Chool Kim, Jae Hong Seo
J Korean Pediatr Soc. 2000;43(12):1621-1625.   Published online December 15, 2000
Congenital epulis of the newborn refers to a very rare gingival tumor that occurs along the anterior alveolar ridge in newborn infants. We report a neonate with 3¡¿2¡¿1.5cm mass protruding from the mouth. This was a pinky, red solid pedunculated mass, attached to the maxillar left canine region of the alveolus at birth. The tumor's large size partially obliterated the...
Langerhans` Cell Histiocytosis Associated wjth Secondary Aneurysmal Bone Cyst, One Case Report
Yong-Koo Park, Kyung Nam Ryu, Won Leem
J Korean Pediatr Soc. 2000;43(12):1626-1629.   Published online December 15, 2000
Seconnday aneurysmal bone cyst is the disease that occurrs in the primary bone tumor and/or tumorus conditions Meticulous search is needed to make a correct diagnosis which dose not overlook the primary diseases. We have experinced an osteolytic lesion on the 7-year-old boy on his skull bone. Plain radiography of the skull revealed osteolytic lesion in the parieto-occipital bone. On...
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