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Volume 43(5); May 2000
Medical Lecture Course
Recent Advances in Gastroesophageal Reflux Disease of Children
Jeong Wan Seo
J Korean Pediatr Soc. 2000;43(5):599-604.   Published online May 15, 2000
Original Articles
The Utility of Serum Prealbumin as a Biochemical Marker for Nutritional Adequacy in Neonates
Ji A Jung, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee
J Korean Pediatr Soc. 2000;43(5):605-610.   Published online May 15, 2000
Purpose : The purpose of this study was to determine the utility of serum prealbumin as a biochemical marker for nutritional adequacy in neonates. Methods : From March 1998 to May 1999, 71 fullterm(54 AGA, 9 LGA, 8 SGA) and 46 preterm neonates were enrolled. The correlations among prealbumin, albumin, birth weight and gestational age were obtained. Serum concentrations of albumin...
The Clinical Characteristics and Gene Analysis of Korean Gaucher Disease with Central Nervous System Involvement
Hoi Seok Choi, Sung Hwan Kim, Hiroyuki Ida, Hyun Ju Kim
J Korean Pediatr Soc. 2000;43(5):611-618.   Published online May 15, 2000
Purpose : We performed the study to determine the clinical characteristics and natural history of Gaucher disease with CNS involvement in Korea as well as to determine whether gene analysis would be helpful in the identification of neuronopathic Gaucher disease. Methods : We described the initial symptom, clinical manifestations, age of onset, clinical neurophysiologic findings and brain MRI findings from the...
Clinical Study of Recurrent Parotitis in Children
Sam-Hwa Yim, Kye-Nam Yoon, Kyung-Yil Lee, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Jin-Han Kang, Kyung-Tai Whang
J Korean Pediatr Soc. 2000;43(5):619-624.   Published online May 15, 2000
Purpose : Recurrent parotitis is defined as a recurrent parotid inflammation, generally associated with sialectasis of the parotid gland. It can often be misdiagnosed as recurrent mumps. We studied the clinical and laboratory features of recurrent parotitis. Methods : Outpatient clinical records of 23 cases were analyzed retrospectively between April 1993 and March 1999. Follow-up after the last outpatient clinic...
The Relation between Antibiotic Use and Changes of Antimicrobial Resistance of Gram Negative Bacilli Isolated in Chonbuk National University Hospital(1993-1997)
Min Ki Chang, Jung Min Chu, Hae Soo Lee, Jung Soo Kim
J Korean Pediatr Soc. 2000;43(5):625-631.   Published online May 15, 2000
Purpose : Antimicrobial resistance has become a major medical and public health problem. This study was performed to evaluate the changes in antimicrobial susceptibility patterns. Methods : The susceptibility of 8,224 recent clinical isolates during a 5-year period from 1993 to 1997 were tested against 8 antimicrobial agents. Antimicrobial susceptibility test was performed by disc diffusion method. Results : E. coli...
Isolation of Causative Microorganism and Antimicrobial Susceptibility Test in Impetigo Developed in the Past Four Years
Hyun Jeong Lee, Sang Jung Lee, Seog Jun Ha, Chang Kyu Oh, Jin Wou Kim
J Korean Pediatr Soc. 2000;43(5):632-637.   Published online May 15, 2000
Purpose : Recently, Staphylococcus aureus has been reported as the principal microorganism isolated from impetigo, showing variable degrees of antimicrobial resistance. The aim of this work was to study the causative organism of impetigo the their antimicrobial susceptibility developed in impetigo in the past four years. Methods : We performed bacterial cultures and antimicrobial susceptibility tests in 73 patients with impetigo...
Comparative Reactivity of 2 TU and 5 TU PPD Skin Tests
Dae Sun Jo, Kyeong Mee Lee, Dae-Yeol Lee, Jung Soo Kim
J Korean Pediatr Soc. 2000;43(5):638-643.   Published online May 15, 2000
Purpose : These days 5 TU purified protein derivative(PPD) is substituted with 2 TU PPD for the tuberculin skin test, a test essential in the diagnosis of tuberculosis in pediatric population. However, there had been no adequate criteria for the positivity of 2 TU PPD skin test. This study was performed to clarify the criteria of positive reactivity of 2...
Typing of Epstein-Barr Virus in Healthy Korean Children and Adults
Jin Han Kang, Jae Kyun Hur, Joeng Hyun Kim, Ahn Hee Lee
J Korean Pediatr Soc. 2000;43(5):644-649.   Published online May 15, 2000
Purpose : Recently, the list of Epsterin-Barr Virus(EBV)-associated diseases has been growing. It is now known that there are two types(type 1 & 2) of EBV, but it has yet to be fully investigated as to whether type B EBV differs in any way from type A virus in terms of geographical distribution or disease association. We performed this study...
Effects of Umbilical Arterial Catheterization on Intestinal Hemodynamics
Sejung Sohn, Su Jung Choi, Jung An Yang, Eun Ae Park
J Korean Pediatr Soc. 2000;43(5):650-657.   Published online May 15, 2000
Purpose : An umbilical arterial catheter(UAC) in the high position reduces the lumen of the aorta and may thereby impair blood supply to the intestine. Effects of UAC on intestinal blood flow were investigated. Methods : With the measurement of the aortic diameter, pulsed Doppler ultrasonography was performed in 23 fasting newborns to measure blood flow velocities(peak systolic velocity, end-diastolic velocity,...
Outcome of Cardiac Complication in Patients of Kawasaki Disease Treated with High-dose Gammaglobulin
Hyang-Sook Kim, Jong-Tae Kim, Ji-Yon Lee, Jo-Won Jung, Ki-Soo Pai
J Korean Pediatr Soc. 2000;43(5):658-666.   Published online May 15, 2000
Purpose : We performed the study to evaluate the risk factors associated with cardiac complication and the outcome of coronary lesions after high-dose(2g/kg, 1dose) gammaglobulin(IVIG) treatment in patients with Kawasaki disease(KD). Methods : Retrospective studies were performed on 338 cases of KD treated with high-dose IVIG at this hospital from May 1994 to March 1999. Results : Among 338 patients,...
Clinical and Pathologic Features of Nodular Duodenitis in Children
Heon Sang Kim, Jin Hoon Chun, Yong Joo Kim, Se Jin Chang, Eun Kyung Hong
J Korean Pediatr Soc. 2000;43(5):667-673.   Published online May 15, 2000
Purpose : Nodular duodenitis is defined as two or more erythematous nodules in the duodenum, with surrounding inflammation and with or without apical erosions. But the clinical features and natural history of nodular duodenitis remain largely undefined, therefore we examined clinical, endoscopic and pathologic features of nodular duodenitis in children to find about its natural history, relationship between endoscopic and...
Change of Peripheral Blood CD5+ B Lymphocytes in Early Neonatal Period
Ye Ho Lee, Bin Cho, Department of Pediatrics, College of Medicine, Cat , Kyung Tai Whang
J Korean Pediatr Soc. 2000;43(5):674-678.   Published online May 15, 2000
Purpose : This study was aimed to investigate age-related changes of CD5+ B lymphocytes in healthy Korean neonates. Methods : Sixty healthy neonatal infants were enrolled in this study; at birth(n=10), day 1(n=10), day 2(n=10), day 3(n=10), day 4(n=10) and day 5(n=10). Phenotypic analysis of CD5+ B lymphocytes was performed on blood samples using standard flow-cytometric techniques. Results : The percentage of...
Apolipoprotein E Polymorphism and Plasma Lipid Levels in Obese Children
Myoung Hee Han, Sun Jun Kim
J Korean Pediatr Soc. 2000;43(5):679-685.   Published online May 15, 2000
Purpose : The increased prevalence of dyslipoproteinemia in obese children probably contributes to the high risk of cardiovascular disease associated with being overweight. The genetic makeup is possible one of the factors that influence the impact of obesity on lipid metabolism. A relation between apolipoprotein E(Apo E) polymorphism and lipid metabolism has been convincingly demonstrated in large population. The purpose...
Characteristics of Childhood Asthma According to the Onset of Wheezing
Yoon Jeong Kim, Bong Seong Kim, Soo-Jong Hong
J Korean Pediatr Soc. 2000;43(5):686-693.   Published online May 15, 2000
Purpose : To understand the characteristics of early childhood asthma, we evaluated and compared the characteristics between early persistent wheezers and late wheezers. Methods : From January, 1998 to December, 1998, 106 children aged six to seven years were divided into three groups according to the onset of wheezing : Early persistent wheezers(n=36) who had wheezing both before three years of...
Case Reports
A Case of Partial Trisomy 9 by Balanced Maternal Translocation
Mi Kyung Kim, Young Kyoo Shin, Baik Lin Eun, Sang Hee Park, Sun Hwa Park, Soon Hyuk Lee
J Korean Pediatr Soc. 2000;43(5):700-703.   Published online May 15, 2000
Trisomy 9p syndrome was first described by Rethore et al in 1970 and about 100 cases have been reported since. The phenotypic spectrum of this syndrome is characterized by craniofacial malformation, facial deformity, skeletal and dermatoglyphic anomalies with variable degrees of mental retardation. We experienced a case of partial trisomy 9 syndrome in a 15-month-old female who had multiple congenital...
Two Cases of Successful Treatment with Atropine Sulfate in Persistent Vomiting beyond Pyloromyotomy of Infantile Hypertrophic Pyrolic Stenosis
Won Jung Kim, Min Jung Kim, Woo Jae Jo, Jae Young Kim, Sung Won Kim
J Korean Pediatr Soc. 2000;43(5):704-709.   Published online May 15, 2000
Infantile hypertrophic pyloric stenosis(IHPS) is the most common condition requiring abdominal surgery in early infancy, and is caused by hypertrophied pyloric muscle. The development of successful surgical treatment in the early 1900s by Fredet and Ramstedt made it possible for infants worldwide to survive. Modern pediatric anesthetic techniques have virtually eliminated mortality from surgical management. Atropine sulfate is a cholinergic...
A Case of Neuromyelitis Opitica(Devic Disease)
Hee Taeg Kim, Yun Jong Kang
J Korean Pediatr Soc. 2000;43(5):710-714.   Published online May 15, 2000
Neuromyelitis optica(Devic disease) is a rare demyelinating disorder of unknown etiology in which unilateral or bilateral optic neuritis and transverse myelitis occur within 8 weeks. The disease has no clinical involvement beyond the spinal cord or optic nerves. This illness occurs more commonly in adults than in children. The prognosis is better in children than in adults. The authors experienced...
A Case of Fibromuscular Dysplasia Associated with Hypertensive Encephalopathy
Ju Suk Lee, Sang Nam Bae, Sang Ook Nam, Su Young Kim, Hee Ju Park
J Korean Pediatr Soc. 2000;43(5):715-719.   Published online May 15, 2000
Fibromuscular dysplasia is the single leading etiology of renovascular hypertension in children. We report an eight-year-old girl who was admitted for generalized tonic seizure with fibromuscular dysplasia of right renal artery. On admission, she presented hypertension and altered mentality. She had suffered from intermittent severe headache for the past year. Renal angiography of right renal artery showed stenosis, beaded pattern...
A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
J Korean Pediatr Soc. 2000;43(5):720-724.   Published online May 15, 2000
Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG...
A Case of Congenital Long QT Syndrome with Reccurent Syncope
Jong Hwa Hwang, Hong Bae Kim
J Korean Pediatr Soc. 2000;43(5):725-729.   Published online May 15, 2000
Congenital long QT syndrome(LQTS) is a disease characterized by prolongation of ventricle repolarization and by the occurrence, usually during emotional or physical stress, of life-threatening arrhythmias that lead to sudden death in most symptomatic and untreated patients. Two variants have been initially identified : the original Jervell and Lange-Nielsen syndrome of congenital deafness and autosomal recessive inheritance, and the more...
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