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Volume 44(10); Oct 2001
Clinical Lecture
Utility Change of Health Care Services after Separation of Dispensary from Medical Practice
Kyoo Duck Lee
J Korean Pediatr Soc. 2001;44(10):1095-1102.   Published online October 15, 2001
Original Articles
Relationship between Serum Leptin Levels and Other Predictors in Obese Children
Se Jin Park, Ki Won Park, Young Mi Hong
J Korean Pediatr Soc. 2001;44(10):1103-1111.   Published online October 15, 2001
Purpose : The product of the ob gene, leptin is an adipocyte specific hormone that might be involved in the regulation of food intake by the central neuroendocrine system. Recent studies reported that serum leptin concentrations were correlated with Body mass index(BMI) and other obesity measurements. The aims of this study were to evaluate leptin concentrations according to degree of...
Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease
Seon Young Kim, Chang Yee Cho, Young Youn Choi
J Korean Pediatr Soc. 2001;44(10):1112-1118.   Published online October 15, 2001
Purpose : This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group. Methods : Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into...
The Relationship of Maternal Disorder with Neonatal Cord Blood Leptin - Preeclampsia, Diabetes Mellitus, Antenatal Steroid Treatment -
Seon Mi Park, Eun Young Kim, Yeong Bong Park, Sang Kee Park
J Korean Pediatr Soc. 2001;44(10):1119-1126.   Published online October 15, 2001
Purpose : Leptin, the product of the ob gene is primarily by adipose tissue but also by the human placenta. Leptin may also have a role as a regulator of fetal growth and development during normal pregnancy as well as in pregnancies associated with anomalous fetal growth. Our study aimed to discover whether or not leptin concentration in neonatal cord...
Clinical Efficacy of Selective Fetal Echocardiography
Su Young Hong, Ji Eun Ban, Young Seok Lee, Hyoung Doo Lee
J Korean Pediatr Soc. 2001;44(10):1127-1134.   Published online October 15, 2001
Purpose : The aims of this study was to assess the indication, diagnostic, accuracy and prognostic influence of fetal echocardiography. Methods : From 1995 to 1999, 283 pregnancies were evaluated with fetal echocardiography at Dong-A University Hospital. We reviewed medical records included indication, fetal echocardiographic findings, postnatal echocardiographic findings, methods of treatment and outcome of prenataly diagnosed patients. Results : Family...
Electrophysiologic Study of Cardiac Conduction System in Children
Chae Ok Shin, Myung Chul Hyun
J Korean Pediatr Soc. 2001;44(10):1135-1140.   Published online October 15, 2001
Purpose : Pediatric cardiac arrhythmias are increasing but there is no normal values of cardiac electrophysiologic studies(EPS) in Korean children. So we performed cardiac EPS in children undergoing cardiac catheterization for mild congenital heart disease without cyanosis and ECG abnormality. Methods : We studied 24 children(male : 9, female : 15) with mild congenital heart disease(PDA : 10, VSD : 8,...
A Study on the Disease Course and Prognosis of Cyclic Vomiting Syndrome
Hye Ran Yang, Jae Sung Ko, Jeong Kee Seo
J Korean Pediatr Soc. 2001;44(10):1141-1156.   Published online October 15, 2001
Purpose : To describe clinical features of cyclic vomiting syndrome(CVS), managements during episodes, prophylactic drugs as long term therapy and to investigate the disease course and prognostic factors of CVS. Methods : Thirty two children who fulfilled the diagnostic criteria of CVS and who presented to Seoul National University Children's Hospital from March 1989 to December 2000, were included. Data were...
Nitroblue Tetrazolium(NBT) Test as a Screening Test of Urinary Tract Infection in Children
Nyun Huh, Chang Hee Oh, Je Woo Kim, Phil Soo Oh, Hae Sun Yoon, Won Keun Song
J Korean Pediatr Soc. 2001;44(10):1157-1161.   Published online October 15, 2001
Purpose : It has been reported that the Nitroblue Tetrazolium(NBT) test is more accurate than the urine pH, leukocyte esterase and nitrite test as a screening test of urinary tract infection (UTI). The purpose of this study is to compare the NBT test with other screening tests and evaluate the clinical usefulness of the NBT test as a screening test. Methods...
Evoked Potentials and Cranial Ultrasonography as a Prognostic Method in Newborn with Asphyxia
Hyung Jin Kim, Hee Kang, Byoung Min Choi, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 2001;44(10):1162-1167.   Published online October 15, 2001
Purpose : This study was aimed at finding a diagnostic tool which is useful in predicting the neurologic outcome of the asphyxiated newborns. Methods : 31 newborns with asphyxia were evaluated by brainstem evoked potentials and cranial ultrasonography(CUS). During the neonatal follow-up, we evaluated the development of the babies with Bayley Scale of Infant Development II and INFANIB on corrected age...
Serum Level of G-CSF and GM-CSF and CFU-GM Response to Hematopoietic Growth Factors in a Patient with Cyclic Neutropenia
Youn-Kyung Lee, Seok-Hun Kim, Kwang-Woo Kim, Soon Lee, Heung-Sik Kim, Dong-Seok Chun, Kun-Soo Lee
J Korean Pediatr Soc. 2001;44(10):1168-1175.   Published online October 15, 2001
Purpose : Serum levels of G-CSF and GM-CSF were measured and CFU-GM assay using G- CSF, GM-CSF and SCF was conducted to evaluate the influence of hematopoietic growth factor on the precursor cells of cyclic neutropenia. Methods : A 7-year-old male with cyclic neutropenia was studied. Marrow mononuclear cells were isolated at neutrophil nadir and recovery and cultured in methylcellulose media...
Case Reports
A Congenital Cutis Laxa Fatality Caused by Early Onset Pulmonary Emphysema
Tae Won Lee, Seung Jun Seong, Yoo Mi Jeung, Jae Bok Kim, Eun Ryoung Kim, Yong Su Yoon
J Korean Pediatr Soc. 2001;44(10):1176-1181.   Published online October 15, 2001
Cutis laxa is a rare disorder of the elastic tissue characterized by loosely hanging and folded skin giving a premature senile appearance, often with internal organ involvement. Recently, we experienced a case of cutis laxa in a neonate. The patient who presented with dyspnea and loose skin at birth was delivered by Cesarean section in our hospital. He was the...
A Case of Nemaline Myopathy
Bu Jin Kim, Im Jeong Choi, Dae Sung Kim, Sang Ook Nam
J Korean Pediatr Soc. 2001;44(10):1182-1186.   Published online October 15, 2001
Childhood onset nemaline myopathy, first described in 1963 by Shy, et al and Conen, et al, is rare congenital myopathy, characterized by nonprogressive or slowly progressive muscle weakness associated with rod-like structures in muscle fibers, often with dysmorphic features. This myopathy was confirmed by muscle biopsy. The light microscopic features noted generally small round fibers that showed variation in size...
Nonrhizomelic Type of Chondrodysplasia Punctata Suspected in the Brothers
Jeum-Su Kim, Hae-Seoung Jung, Yong-Suk Kim, Chan-Hoo Park, Myoung Bum Choi, Hyang-Ok Woo, Hee-Shang Youn
J Korean Pediatr Soc. 2001;44(10):1187-1192.   Published online October 15, 2001
Chondrodysplasia punctata is a heterogenous skeletal dysplasia characterized by small focal calcifications in articular and other cartilages in infancy, with subsequent epiphysial dysplasia and associated anomalies of the face, eyes, and skin. Chondrodysplasia punctata is classified with autosomal recessive rhizomelic type, autosomal dominant nonrhizomelic type(Conradi-Hunermann type), and X-linked dominant type. These types have different clinical manifestations respectively. We report cases...
A Case of Annular Pancreas and Endocardial Cushion in the Abscence of Down Syndrome
Hae Jung Cho, Jeong Jin Yu, Yoo Ryung Lee, Chul Moon
J Korean Pediatr Soc. 2001;44(10):1193-1196.   Published online October 15, 2001
Annular pancreas is a rarely found gastrointestinal tract malformation, and is frequently associated with Down syndrome. Endocardial cushion defect is a type of congenital heart disease, commonly also related to Down syndrome. However, a combination of endocardial cushion defect with annular pancreas has not been reported previously. We recently experienced such a case in 2 month old boy. Moreover Down...
A Case of Menetrier's Disease Associated with Cytomegalovirus Infection
Ju Rae Cho, Sung Kil Kang, Yun Hee Kim, Yon Ho Choe
J Korean Pediatr Soc. 2001;44(10):1197-1200.   Published online October 15, 2001
We report the case of a 4 year-old boy with Menetrier's disease, who was presented with edema and hypoalbuminemia. Gastroduodenal endoscopy showed the characteristic features of giant hypertrophy of the gastric rugae and large quantities of adherent gelatinous material. Histologic findings revealed foveolar hyperplasia. The presence of CMV infection was identified by serology. His symptoms resolved spontaneously, and he has...
Fanconi-Bickel Syndrome Presented with Diabetes Mellitus and Galactosemia : Identification of a Novel Mutation in the GLUT2 Gene
You-Jeong Kim, Sun-Hee Rim, Young-Lim Shin, Han-Wook Yoo
J Korean Pediatr Soc. 2001;44(10):1201-1205.   Published online October 15, 2001
Fanconi-Bickel syndrome is a rare autosomal recessive disorder of the carbohydrate metabolism recently demonstrated to be caused by mutations in GLUT2, the gene for the glucose transporter protein 2 expressed in the liver, pancreatic β islet-cells, intestine and kidney. Typical clinical and laboratory findings of Fanconi-Bickel syndrome are hepatomegaly secondary to glycogen accumulation, glucose and galactose intolerance, fasting hypoglycemia, a...
Two Cases of HHH Syndrome in Siblings
Min Ho Hwang, Bo Sun Kim, Dong Hwan Lee
J Korean Pediatr Soc. 2001;44(10):1206-1210.   Published online October 15, 2001
Hyperornithinemia-hyperammonemia-homocitrullinuria(HHH) syndrome is a rare autosomal recessive disorder caused by a defect in the urea cycle. Protein intolerance, mental retardation, seizure, ataxia, and stupor are characteristic symptoms. Patients showing these symptoms may also present symptoms of acute hepatic disease at the same time. When fed with a high protein diet, they may refuse to eat, vomit, become lethargic, or go...
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