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Volume 48(10); Oct 2005
Clinical Lectures
Can We Predict How Often Nephrotic Syndrome will Relapse into the Patients?
Mee Kyung Namgoong
Korean J Pediatr. 2005;48(10):1033-1037.   Published online October 15, 2005
Pediatric nephrotic syndrome is a well-known illness for its high relapsing rate. If we can predict the relapsing rate and the responses to the steroid therapy of individual patients with nephrotic syndrome, the predictability will be helpful in building a therapeutic plan. Here is my review of research articles on the risk factors for the prediction of relapsing nephrotic syndrome.
Airway Remodelling in Asthma
Dae Hyun Lim
Korean J Pediatr. 2005;48(10):1038-1049.   Published online October 15, 2005
Asthma is characterized by a chronic inflammatory disorder of the airways that leads to tissue injury and subsequent structural changes collectively called airway remodelling. Characteristic changes of airway remodelling in asthma include goblet cell hyperplasia, deposition of collagens in the basement membrane, increased number and size of microvessels, hypertrophy and hyperplasia of airway smooth muscle, and hypertrophy of submucosal glands....
Original Articles
Relactation in the Lactation Clinic
Su Jin Cho, Keun Lee
Korean J Pediatr. 2005;48(10):1050-1054.   Published online October 15, 2005
Purpose : Relactation refers to the re-establishment of a milk supply and nursing after the cessation of nursing for a variable period. We aimed to analyze the practical issues related to successful relactation in the lactation clinic. Methods : The medical records of 51 mothers who had visited the lactation clinic for relactation were retrospectively analyzed. Breastfeeding greater than 90%...
Growth Patterns of Breast Fed and Formula Fed Infants
Ju Young Kwak, Jun Young Park, He Jin Lee, Hi Jin Jung, Sang Hi Son, Soo Jin Jung
Korean J Pediatr. 2005;48(10):1055-1060.   Published online October 15, 2005
Purpose : The purpose of this study is to compare the growth pattern of breast fed and formula fed infants in the first 1 year of life. Methods : Anthropometric data(weight, length, head circumference) of at birth, 1, 3, 6, 9 and 12 months were collected by chart review and characteristics of subjects were collected by questionnaires. Among 358 infants,...
Clinical Analysis of the Pediatric Patients Seen in the Emergency Medical Center
Hee Jung Lee, So Yoon Park, Young Hwan Lee, Byung Soo Do, Sam Bum Lee
Korean J Pediatr. 2005;48(10):1061-1067.   Published online October 15, 2005
Purpose : We studied a clinical analysis of pediatric patients who visited the emergency medical center of Yeungnam University Hospital to compare the characteristics of pediatric emergency patients after year 2000 with the previous studies. Methods : We reviewed 7,034 children under the age of 15 years who visited the emergency medical center of Yeungnam University Hospital during the 2...
Comparision of PCR-RFLP, PCR-SSCP, Amplication Refractory Mutation System(ARMS) in Leu72Met Polymorphism of Ghrelin Gene
Ju Sung Kang, Se Rim Kim, Sun Young Kim, Chan Uhng Joo, Soo Chul Cho, Pyoung Han Hwang
Korean J Pediatr. 2005;48(10):1068-1075.   Published online October 15, 2005
Purpose : The role of ghrelin, which promotes the secretion of growth hormone, was not well known until now. Recently it was found that the mutation of ghrelin gene is related to obesity and diabetes. This study is to find the screening method that can easily and effectively detect the polymorphism of Leu72Met in ghrelin gene of obesity patients and...
Affecting Factors of Insulin Resistance in Obese Children and Adolescents
Duk Hee Kim, Ho Seon Eun, In Kyung Choi, Ho Seung Kim, Bong Soo Cha, Dong Kee Kim
Korean J Pediatr. 2005;48(10):1076-1081.   Published online October 15, 2005
Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods...
The Usefulness of the Abdominal Computerized Tomography for the Diagnosis of Childhood Obesity and Its Correlation with Various Parameters of Obesity
Yoon Hee Shim, Su Jin Cho, Jung Hyun Rhyu, Young Mi Hong
Korean J Pediatr. 2005;48(10):1082-1089.   Published online October 15, 2005
Purpose : Abdominal obesity is encountered as a risk factor for cardiovascular diseases. However, the anthropometric cut-off value to estimate the cardiovascular risk, has not been suggested. This study was designed to find the relationship between the abdominal fat and various parameters of obesity to find the cardiovascular risk factors related to abdominal obesity and to establish practical methods to...
Comparison of Clinical Progress between Single- and Multiple-dose Surfactant Treatment in Neonatal Respiratory Distress Syndrome
Chang Hee Kil, Ho Sang Jeon, Chong Woo Bae
Korean J Pediatr. 2005;48(10):1090-1095.   Published online October 15, 2005
Purpose : In the case of serious respiratory distress syndrome(RDS) or relapse of clinical appearances after single treatment, we obtained more effective results with multiple-dose surfactant replacement therapy. We carried out this investigation for comparing and observing clinical progress between single-dose(group S) and multiple-dose(group M) pulmonary surfactant treatment group of neonatal RDS. Methods : We investigated 48 neonates who were...
A Study on the Effects of Early Surfactant Replacement and Gentle Ventilation in the Treatment of Respiratory Distress Syndrome
Yong Suk Lee, Ji Hye Lee, Sang Geel Lee
Korean J Pediatr. 2005;48(10):1096-1101.   Published online October 15, 2005
Purpose : Recently, early surfactant replacement and tidal volume based gentle ventilation has been a fundamental treatment of respiratory distress syndrome(RDS). The aims of this study were to survey the changes in ventilator care duration and rate of complication in RDS groups. Methods : We performed a retrospective study of 255 newborn infants less than 1,500 g admitted to the...
Etiology, Management, and Prognosis of Severe Hyperbilirubinemia (Serum Bilirubin Level=25 mg/dL) in Newborn
Jong Hee Hwang, Ji Hyun Lee, Yu Jin Kim, Su Hyun Koo, Jang Hun Lee, Chang Won Cho, Yun Sil Chang, Won Soon Park
Korean J Pediatr. 2005;48(10):1102-1106.   Published online October 15, 2005
Purpose : The present study examined the etiology, management, and the difference of prognosis according to methodology of treatment in severe hyperbilirubinemia with total serum bilirubin levels of more than 25 mg/dL. Methods : Medical records of severe hyperbilirubiemia in newborns(serum level=25 mg/dL) admitted to the NICU of Samsung Medical Center between October 1994 and June 2004 were reviewed retrospectively. Infants...
A Domestic Outbreak of Bacterial Dysentery Caused by Extended-Spectrum β-Lactamase(ESBL)-producing Shigella sonnei
Hyun Taek Lim, So Hee Lee, Jung Hwa Lee, Jeong Eun Kim, Kyo Sun Kim, Eun Ju Jeong, Seung Hyun Lee, Chang Gyu Kang, Seong Jin Hong
Korean J Pediatr. 2005;48(10):1107-1115.   Published online October 15, 2005
Purpose : An outbreak of ESBL-producing Shigella sonnei enteritis was unprecedented not only in Korea but throughout the world in the past. We intended to devise a management guideline for ESBL-producing shigellosis based on analysis of clinical manifestations and response to therapy. Methods : We analyzed 103 patients who were admitted to the hospital with acute GI symptoms and were...
Clinical Study of Rotavirus Gastroenteritis in the Last 2 Years
Hyoung Sik Kim, Myong Wan Jang, Cheol Hong Kim, Hyun Hee Lee, Hwang Jae Yoo
Korean J Pediatr. 2005;48(10):1116-1120.   Published online October 15, 2005
Purpose : Although the rotavirus-related neonatal death occurred in western part of Kyeonggi Province recently, there were just a few reports about rotavirus gastroentertis in domestic since 2000. We proposed to investigate changes of epidemiology and clinical features of rotavirus gastroenteritis for the last 2 years. Methods : We selected 166 patients diagnosed as gastroenteritis from January, 2002 to July,...
Clninical Features of Rotaviral Gastroenteritis in Neonates
Shin-I Park, Hae Oak Kwon, Jun Ho Lee, Su Jin Jung
Korean J Pediatr. 2005;48(10):1121-1125.   Published online October 15, 2005
Purpose : Rotavirus is the main cause of infantile diarrheal disease worldwide, especially in patients 3-24 months of age. Infants younger than 3 months of age are relatively protected by transplacental antibody. So the purpose of this study is to evaluate the clinical features and severity of neonatal rotaviral gastroenteritis less than 1 month of age. Methods : A retrospective chart...
Relationship between △FVC(% fall in FVC at the PC20 Dose of Methacholine) and Serum Eosinophil Cationic Protein(ECP) in 6-8 Year Old Children with Asthma
Dong In Suh, Jinho Yu, Young Yoo, Do Kyun Kim, Hee Kang, Young Yull Koh
Korean J Pediatr. 2005;48(10):1126-1131.   Published online October 15, 2005
Purpose : Bronchial hyperresponsiveness(BHR) is considered a hallmark of asthma. Increased levels of eosinophil cationic protein(ECP) have been identified in serum of asthma patients. Several studies have examined the relationship between serum ECP and bronchial responsiveness, expressed as methacholine PC20 in asthmatic patients, with conflicting results. The aims of this study were to examine the relationship between serum ECP and...
Clinical and Laboratory Features of Korean Mucopolysaccharidoses (MPSs)
Woo Yun Sohn, Jee Hyun Lee, Kyung Hoon Paik, Eun Kyoung Kwon, Ahn Hee Kim, Dong Kyu Jin
Korean J Pediatr. 2005;48(10):1132-1138.   Published online October 15, 2005
Purpose : The mucopolysaccharidoses (MPSs) are a heterogeneous group of lysosomal storage disorders. They are caused by a deficiency of the enzymes involved in the degradation of glycosaminoglycans. Early recognition is important because recombinant enzyme replacement therapy is now available for MPS. We studied the clinical characteristics of 80 MPS children with the object of determining the epidemiological, clinical and...
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Korean J Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Case Report
Transcatheter Closure of a Residual Shunt after Surgical Repair of Traumatic Ventricular Septal Defect
Hee Jeong Jeong, Han Hyuk Lim, Jae Hyun Yu, Jae Hwan Lee, Hong Ryang Kil
Korean J Pediatr. 2005;48(10):1143-1147.   Published online October 15, 2005
The traumatic ventricular septal defect (VSD) is a rare but potentially life threatening complication of chest wall injury. The traumatic VSD occurs in up to 4.5% of penetrating cardiac trauma. Most of the patients are usually operated on because of heart failure and/or significant left-to-right shunt. The feasibility of surgical repair under cardiopulmonary bypass may be affected by coexisting pulmonary,...
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