- Review Articles
- Treatment of steroid-resistant pediatric nephrotic syndrome
- Hee Gyung Kang
- Clin Exp Pediatr. 2011;54(8):317-321. Published online August 31, 2011
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Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these children, renal replacement therapy can also be...
- Complications of nephrotic syndrome
- Se Jin Park, Jae Il Shin
- Clin Exp Pediatr. 2011;54(8):322-328. Published online August 31, 2011
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Nephrotic syndrome (NS) is one of the most common glomerular diseases that affect children. Renal histology reveals the presence of minimal change nephrotic syndrome (MCNS) in more than 80% of these patients. Most patients with MCNS have favorable outcomes without complications. However, a few of these children have lesions of focal segmental glomerulosclerosis, suffer from severe and prolonged proteinuria, and...
- Original Articles
- Clinical characteristics and outcomes among pediatric patients hospitalized with pandemic influenza A/H1N1 2009 infection
- Eun Lee, Ju-Hee Seo, Hyung-Young Kim, Shin Na, Sung-Han Kim, Ji-Won Kwon, Byoung-Ju Kim, Soo-Jong Hong
- Clin Exp Pediatr. 2011;54(8):329-334. Published online August 31, 2011
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Purpose The purpose of this article is to describe the clinical and epidemiologic features and outcomes among children hospitalized with pandemic influenza A/H1N1 2009 infection.
Methods We retrospectively reviewed the charts of hospitalized pediatric patients (<18 years) diagnosed with pandemic influenza A/H1N1 2009 infection by reverse-transcriptase polymerase chain reaction at a tertiary hospital in Seoul, Korea, between September 2009 and February 2010.
Results A total...
- Polymorphisms of methylenetetrahydrofolate reductase are not a risk factor for Kawasaki disease in the Korean population
- Kyung Lim Yoon, Jin Hee Ko, Kye Shik Shim, Mi Young Han, Sung Ho Cha, Su Kang Kim, Joo Ho Jung
- Clin Exp Pediatr. 2011;54(8):335-339. Published online August 31, 2011
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Purpose Hyperhomocysteinemia is known as a risk factor for atherosclerosis. Preclinical arteriosclerosis is noted and premature atherosclerosis is known to be accelerated in Kawasaki disease (KD) patients. Genetic polymorphisms in the 5,10-methylenetetrahydrofolate reductase (
MTHFR ) gene result in elevated plasma homocysteine concentrations and are known to be associated with the development of coronary artery disease. Our hypothesis is that single nucleotide polymorphisms...
- Log-transformed plasma level of brain natriuretic peptide during the acute phase of Kawasaki disease is quantitatively associated with myocardial dysfunction
- Sunhee Bang, Jeong Jin Yu, Myung-Ki Han, Hong Ki Ko, Sail Chun, Hyung Soon Choi, Young-Hwue Kim, Jae-Kon Ko, In-Sook Park
- Clin Exp Pediatr. 2011;54(8):340-344. Published online August 31, 2011
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Purpose Brain natriuretic peptide (BNP) has been considered a biochemical marker for myocarditis in Kawasaki disease. We performed this study to determine its quantitative significance.
Methods We attempted to correlate log-transformed BNP concentrations (log-BNP) and clinical, laboratory, and echocardiographic variables in 81 children with Kawasaki disease. Stepwise multiple linear regression analysis was used to determine the variables independently associated with log-BNP concentration.
Results Serum C-reactive...
- Case Reports
- 2009 H1N1 influenza virus infection and necrotizing pneumonia treated with extracorporeal membrane oxygenation
- Suntae Ji, Ok Jeong Lee, Ji-Hyuk Yang, Kangmo Ahn, Joongbum Cho, Soo In Jeong, Woo-sik Han, Yae-Jean Kim
- Clin Exp Pediatr. 2011;54(8):345-349. Published online August 31, 2011
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A 3-year-old girl with acute respiratory distress syndrome due to a H1N1 2009 influenza virus infection was complicated by necrotizing pneumonia was successfully treated with extracorporeal membrane oxygenation (ECMO). This is the first reported case in which a pediatric patient was rescued with ECMO during the H1N1 influenza epidemic in Korea in 2009.
- Masticator space abscess in a 47-day-old infant
- Eunhee Kim, Ju Hee Jeon, Yoon Hee Shim, Kyu-Seok Lee, So Young Kim, Eun Ryoung Kim
- Clin Exp Pediatr. 2011;54(8):350-353. Published online August 31, 2011
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A 47-day-old male infant presented with fever, poor oral intake, irritability, and right-sided bluish buccal swelling. Contrast-enhanced computed tomography of the neck showed a round mass lesion of about 2.0×1.5 cm that suggested abscess formation in the right masticator space. Ultrasound-guided extraoral aspiration of the abscess at the right masseter muscle was successful. Staphylococcus aureus was identified in the culture...
