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<article article-type="letter" dtd-version="1.0" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">CEP</journal-id>
<journal-title-group>
<journal-title>Clinical and Experimental Pediatrics</journal-title><abbrev-journal-title>Clin Exp Pediatr</abbrev-journal-title></journal-title-group>
<issn pub-type="epub">2713-4148</issn>
<publisher>
<publisher-name>Korean Pediatric Society</publisher-name></publisher></journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3345/cep.2021.01298.r1</article-id>
<article-id pub-id-type="publisher-id">cep-2021-01298-r1</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Correspondence and Reply</subject>
<subj-group subj-group-type="heading">
<subject>Psychiatric/Psychology</subject>
</subj-group></subj-group></article-categories>
<title-group>
<article-title>Association between polycystic ovary syndrome and risk of attention-deficit/hyperactivity disorder in offspring: a meta-analysis</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Rastad</surname><given-names>Hadith</given-names></name>
<xref ref-type="aff" rid="af1-cep-2021-01298-r1"><sup>1</sup></xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0003-1882-5951</contrib-id>
<name><surname>Seifi Alan</surname><given-names>Mahnaz</given-names></name>
<xref ref-type="corresp" rid="c1-cep-2021-01298-r1"/>
<xref ref-type="aff" rid="af1-cep-2021-01298-r1"><sup>2</sup></xref>
</contrib>
<aff id="af1-cep-2021-01298-r1"><label>1</label>Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, <country>Iran</country></aff>
<aff id="af2-cep-2021-01298-r1"><label>2</label>Cardiovascular Research Center, Alborz University of Medical Sciences, Karaj, <country>Iran</country></aff>
</contrib-group>
<author-notes>
<corresp id="c1-cep-2021-01298-r1">Corresponding author: Mahnaz Seifi Alan Cardiovascular Research Center, Alborz University of Medical Sciences, Karaj, Iran Email: <email>m_seifi2012@yahoo.com</email></corresp>
</author-notes>
<pub-date pub-type="collection">
<month>3</month>
<year>2022</year></pub-date>
<pub-date pub-type="epub">
<day>17</day>
<month>2</month>
<year>2022</year></pub-date>
<volume>65</volume>
<issue>3</issue>
<fpage>152</fpage>
<lpage>152</lpage>
<history>
<date date-type="received">
<day>22</day>
<month>08</month>
<year>2021</year></date>
<date date-type="accepted">
<day>28</day>
<month>10</month>
<year>2021</year></date>
</history>
<permissions>
<copyright-statement>Copyright &#x000a9; 2022 by The Korean Pediatric Society</copyright-statement>
<copyright-year>2022</copyright-year>
<license>
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/">http://creativecommons.org/licenses/by-nc/4.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions>
<related-article related-article-type="commentary-article" id="ra1-cep-2021-01536" vol="65" page="85"/>
</article-meta></front>
<body>
<p><bold>To the editor:</bold> We read with great interest a meta-analysis by Maleki et al. &#x0005b;<xref ref-type="bibr" rid="b1-cep-2021-01298-r1">1</xref>&#x0005d; on the association between prenatal excess of androgen exposure in the offspring of mothers with polycystic ovary syndrome (PCOS) and risk of attention-deficit/hyperactivity disorder (ADHD) in them. They found that maternal PCOS increases the offspring risk of ADHD. However, we have to point out a deficiency of this study, we noted that 1 of 6 articles that were included in this study did not meet the eligibility criteria as it&#x02019;s object was different &#x0005b;<xref ref-type="bibr" rid="b2-cep-2021-01298-r1">2</xref>&#x0005d;. Herg&#x000fc;ner et al. &#x0005b;<xref ref-type="bibr" rid="b2-cep-2021-01298-r1">2</xref>&#x0005d; aimed to compare ADHD symptoms between women with PCOS and controls. This deficiency may introduce bias and lead to a false conclusion.</p>
</body>
<back>
<fn-group>
<fn fn-type="conflict"><p><bold>Conflicts of interest</bold></p><p>No potential conflict of interest relevant to this article was reported.</p></fn>
<fn fn-type="financial-disclosure"><p><bold>Funding</bold></p><p>This letter received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.</p></fn>
</fn-group>
<ref-list>
<title>References</title>
<ref id="b1-cep-2021-01298-r1">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name><surname>Maleki</surname><given-names>A</given-names></name>
<name><surname>Bashirian</surname><given-names>S</given-names></name>
<name><surname>Soltanian</surname><given-names>AZ</given-names></name>
<name><surname>Jenabi</surname><given-names>E</given-names></name>
<name><surname>Farhadinasab</surname><given-names>A</given-names></name>
</person-group>
<article-title>Association between polycystic ovary syndrome and risk of attention-deficit/hyperactivity disorder in offspring: a meta-analysis</article-title>
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</element-citation></ref>
<ref id="b2-cep-2021-01298-r1">
<label>2</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name><surname>Herg&#x000fc;ner</surname><given-names>S</given-names></name>
<name><surname>Harmanc&#x00131;</surname><given-names>H</given-names></name>
<name><surname>Toy</surname><given-names>H</given-names></name>
</person-group>
<article-title>Attention deficit-hyperactivity disorder symptoms in women with polycystic ovary syndrome</article-title>
<source>Int J Psychiatry Med</source>
<year>2015</year>
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</element-citation></ref></ref-list>
</back></article>