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Clinical Study of Encephalitis and Encephalopathy in Children.

Journal of the Korean Pediatric Society 1989;32(4):500-510.
Published online April 30, 1989.
Clinical Study of Encephalitis and Encephalopathy in Children.
Dong Hunb Lee, Soo Chun Kim, Sa Jun Chung, Chang Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
소아기 뇌염 (Encephalitis) 과 뇌병증 (Encephalopathy) 의 임상적 관찰
이동협, 김수천, 정사준, 안창일
경희대학교 의과대학 소아과학교실
Received: 16 August 1988   • Accepted: 6 October 1988
This study was undertaken to evaluate the electronencephalographic and clinical findings in 132 cases of encephalitis and encephalopathy in the Department of Pediatrics, Kyung Hee University Hospital for 9 years from Jan. 1979 to Dec. 1987. The results were summerized as follows; 1) The incidence of ecephalitis was 0.46%{86 cases) and the incidence of encephalopathy was 0.25 % (46 cases) among total in-patient (18,671). 2) Male to female ratio was 1.6:1 in encephalitis and 1.3:1 encephalopathy and the peak age was 2 to 6 years in both. 3) Autumn was the most prevalent season (45.3% in encephalitis and 37.0% in encephalopathy) and late summer was the 2nd most common (2.3% in encephalitis and 19.6% in encephalopathy). 4) In etiologies, unknown cases were 58.1 % in ecephalitis and 73.9% in encephalopathy and Japanese B encepahlitis was the most common cause (23.2%) among the known etiologies of encepha. litis. 5) In clinical symptoms and signs, Encephalitis; changes of consciousness (91.9%), seizure (67.4%), fever (58.1%)'" Encephalopathy; changes of consciousness (95.7%), seizure (76.1%), fever (58.7%)'" 이 CSF pleocytosis was found in 96.2% of encephalitis but not in all of encephalopathy and CSF protein values were elevated in 50.6% of ecephalitis and only in 18.6% of encephalopathy and CSF glucose value was decreased in 30.4% of encephalitis and 23.2% of encephalopathy. 7) In brain CT findings, Encephalitis; unremarkable findings (30.5%), brain swelling (30.5%), low density (16.7%)' " Encephalopathy; unremarkable findings (43.5%), brain swelling (30.4%), low density (13.0%) .. ' 8) In the EEG findings, abnormal EEG findings was observed in 81.8 of encephalitis and 81.0% of encephalopathy. 9) In the relationship between EEG findings and prognosis, mortality rate was 11.4% in patients with abnormal EEG findings on admission and the highest mortality rate was observed in patients with EEG findings of suppression pattern among the abnormal EEG findings on admission{50.0%).
Key Words: Encephalitis, Encephalopathy, EEG

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