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Original Article
Nutrition
Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial
Deldar Morad Abdulah, Saad Jbraeil Sulaiman, Zaid Waad Ahmed
Clin Exp Pediatr. 2024;67(4):203-212.   Published online February 19, 2024
Question: Does zinc supplementation along with probiotics affect disease severity or clinical outcomes of children with acute diarrhea?
Findings: This study indicated that zinc supplementation and probiotics had no effect on clinical improvement or disease severity among pediatric patients with acute diarrhea.
Meaning: Children who received probiotics plus zinc recovered faster than those who received probiotics only.
Case Report
A case of acquired acrodermatitis enteropathica with a normal serum zinc level but a low level in the hair
Kyung Il Oh, Jung Hee Kim, Ji Eun Lee, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 2007;50(2):209-212.   Published online February 15, 2007
Acrodermatitis enteropathica (AE) is a rare autosomal recessive disorder of early infancy, and is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Serum zinc levels are usually low in untreated patients and the oral administration of zinc sulfate can clear skin lesions and other symptoms. Although premature and cow`s milk-fed infants are at particular risk of developing AE, there have...
Medical Lecture Course
New Nutritional Concepts of Vitamins and Minerals
Hee-Shang Youn
Clin Exp Pediatr. 2005;48(12):1295-1309.   Published online December 15, 2005
Nowadays, the nutritional deficits are rarely seen in Korea. However, an increased availability of the highly palatable energy dense, nutrient-poor foods increases the risks of obesity and deficits of vitamins and minerals in the general population. Also, optimum intake of vitamins and minerals, which varies with age and genetic back ground, might not suffice the poor, young, obese, and elderly...
Original Article
The Effect of Anticonvulsants on Serum Copper and Zinc Concentrations
Hee Jeong Jeong, Hye Won Youn, Keon Su Lee
Clin Exp Pediatr. 2005;48(4):406-410.   Published online April 15, 2005
Purpose : Anticonvulsants have a number of side effects and some of them may be attributed to a disturbance of serum trace metal homeostasis. Although they are minor building components in tissues, they play important functional roles in the peripheral and central nervous system. We measured serum copper and zinc levels in epileptic children who were treated with anticonvulsants to...
The Levels of Zinc and Neuron-specific Enolase in Febrile Convulsion
Hong Sang Cho, Jun Hun Shin, Ji Yeoung Seo, Cho Ae Lee, Se Hyun Kim, Kyu Young Chae
Clin Exp Pediatr. 2004;47(10):1087-1092.   Published online October 15, 2004
Purpose : To determine the role of zinc in febrile convulsion and to evaluate whether febrile convulsion causes neuronal damage, serum and cerebrospinal fluid(CSF), zinc and CSF neuron-specific enolase(NSE) levels were measured in patients with febrile convulsion, epilepsy and aseptic meningitis. Methods : Three groups were formed as follows : group I : 53 children with febrile convulsion; group II :...
Long-term Clinical Follow-up of Korean Children with Wilson Disease; Twenty Years` Experience
Jin Soo Moon, Jae Sung Ko, Jeong Kee Seo
Clin Exp Pediatr. 2001;44(2):127-138.   Published online February 15, 2001
Purpose : To investigate the clinical features of long-term follow-up, and the treatment responses in Korean children with Wilson disease(WD). Methods : The clinical data from ninety-two children with WD, diagnosed at Seoul National University Hospital from 1976 to 1999, were reviewed. Mean duration of follow-up was 5¡¾4.5 years. We analysed the patient's records based on the clinical manifestations, laboratory findings,...
Zinc and Copper Concentrations and Their Correlation with Protien in Cerebrospinal Fluid of Children with Neurologic Disorders
Myung Joon Cha, Young Joon Kim, Ha Joo Choi, Woo Kap Chung
Clin Exp Pediatr. 1997;40(8):1062-1070.   Published online August 15, 1997
Purpose : The importance of trace elements in their effect on the physiology and pathology of the central nervous system is well recognized. Changes in the concentrations of these elements in the brain could take place in pathological states. Recently, a greater emphasis has been given to the role of trace elements in the function of the nervous system both in normal and pathological...
HDL Cholesterol, Copper, Ceruloplasmin, Zinc, Iron Values of the Blood in Newborn
Kyeong Sang Kim, Chun Hang Lee, Hong Jin Lee, Won Ill Park, Kyung Ja Lee, Tae Hyon Yoon, Won Chan Tae
Clin Exp Pediatr. 1992;35(8):1096-1101.   Published online August 15, 1992
HDL choleaterol, copper, ceruloplasmin, zinc, and iron values of the blood of 85 newborns delivered at hallym University hospital from September, 1989 to February, 1991 were analysed. The results were as follows: 1) The mean value of HDL cholesterol in 50 normal newborns was 31.37¡¾9.47mg/dl, that of copper 80.54¡¾17.54ug/dl, that of ceruloplasmin 11.34¡¾6.37mg/dl, that of zinc 92.81¡¾79.74ug/dl, that of iron 198.98¡¾86.07 ug/dl. 2)...
Transient symptomatic zinc deficiency in a breast-fed, post term infant.
Jin Bok Hwang, Soon Young Song, Woo Hyun Kwon, Chang Ho Han, Hye Li Chung, Young Dae Kwon
Clin Exp Pediatr. 1991;34(1):101-106.   Published online January 31, 1991
Acrdermititis enteropathica is a rare autosomal recessive disorder of zinc absorption and its cardinal symptoms appear at the time of weaning from breast milk which has been referred to as most appropriate formula to prevent and treat this disease. However, recent reports presented Transient Symptomatic Zinc deficiency (TSZD) in infants fed breast milk whom they treated with transitory zinc supplement with no recurrence. We experienced...
Zinc and Copper Contents in Infant Formula.
Ji Tae Choung, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(8):831-836.   Published online August 31, 1987
In 22 samples of infant formula, marketed in Korea, from Apr. 1986 to Oct. 1986, trace elements especially Zn and Cu levels were examined by Atomic Absorption Spectrophotometer. The results were as follows; 1) B-milk, zinc supplemented, contained Zn 863.23 ±50.52 ㎍/100 g, there were no relations with manufacturing date. 2) A-milk and C-milk contained variable levels from absent to 641.19 ㎍/100 g in Zn, 20.02㎍/100g in...
Zinc and Copper Concentrations in Human Milk.
Hwa Young Kim, Hyun Young Ahn, Young Yoon Choi, Tae Ju Hwang, Chull Sohn
Clin Exp Pediatr. 1985;28(4):305-313.   Published online April 30, 1985
Human milk is the most appropriate of all available milks for the human infant since it is uniquely adapted to his or her needs. Zinc and Copper are essential for not only as the constituents of enzymes and their activators, but also growth, development and normal metabolism. Zn and Cu concentrations were observed according to the stage of lactation, parity,...
Serum and Urine Zinc Values in Infectious Diseases.
Yong Tai Suh, Hwa Young Kim, Jai Sook Mah, Tai Ju Hwang
Clin Exp Pediatr. 1984;27(3):237-245.   Published online March 31, 1984
Using atomic absorption spectrophotometer, serum-and urine zinc levels of healthy children aging 4.7 to 6.9 years, and of various infectious diseases, including acute viral hepatitis， tuberculosis, salmonellosis, and shigellosis were determined. The mean zinc levels in healthy children were 76±15.2^g/100 ml in serum and 275土 142.4/ug/L in urine respectively. There was no statistical difference attributable to sex. No remarkable changes...
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