Article 54(1); Jan 2011
Review Articles
Asthma in childhood: a complex, heterogeneous disease
Hai Lee Chung
Clin Exp Pediatr. 2011;54(1):1-5.   Published online January 31, 2011

Asthma in childhood is a heterogeneous disease with different phenotypes and variable clinical manifestations, which depend on the age, gender, genetic background, and environmental influences of the patients. Several longitudinal studies have been conducted to classify the phenotypes of childhood asthma, on the basis of the symptoms, triggers of wheezing illness, or pathophysiological features of the disease. These studies have...

Oral food challenges in children
Hye Yung Yum, Hyeon Jong Yang, Kyung Won Kim, Tae Won Song, Woo Kyung Kim, Jung Hee Kim, Kang Mo Ahn, Hyun Hee Kim, Soo Young Lee, Bok Yang Pyun
Clin Exp Pediatr. 2011;54(1):6-10.   Published online January 31, 2011

Many patients assume that allergic reactions against foods are responsible for triggering or worsening their allergic symptoms. Therefore, it is important to identify patients who would benefit from an elimination diet, while avoiding unnecessary dietary restrictions. The diagnosis of food allergy depends on the thorough review of the patients's medical history, results of supplemented trials of dietary elimination, and in...

Original Articles
Clinical manifestations of CNS infections caused by enterovirus type 71
Cheol Soon Choi, Yun Jung Choi, Ui Yoon Choi, Ji Whan Han, Dae Chul Jeong, Hyun Hee Kim, Jong Hyun Kim, Jin Han Kang
Clin Exp Pediatr. 2011;54(1):11-16.   Published online January 31, 2011
Purpose

Enterovirus 71, one of the enteroviruses that are responsible for both hand-foot-and-mouth disease and herpangina, can cause neural injury. During periods of endemic spread of hand-foot-andmouth disease caused by enterovirus 71, CNS infections are also frequently diagnosed and may lead to increased complications from neural injury, as well as death. We present the results of our epidemiologic research on the...

Percutaneous endoscopic gastrostomy in children
Jye Hae Park, SeonKyeong Rhie, Su Jin Jeong
Clin Exp Pediatr. 2011;54(1):17-21.   Published online January 31, 2011
Purpose

Percutaneous endoscopic gastrostomy (PEG) can improve nutritional status and reduce the amount of time needed to feed neurologically impaired children. We evaluated the characteristics, complications, and outcomes of neurologically impaired children treated with PEG.

Methods

We retrospectively reviewed the records of 32 neurologically impaired children who underwent PEG between March 2002 and August 2008 at our medical center. Forty-two PEG procedures comprising...

Characteristics of late-onset epilepsy and EEG findings in children with autism spectrum disorders
Haneul Lee, Hoon Chul Kang, Seung Woo Kim, Young Key Kim, Hee Jung Chung
Clin Exp Pediatr. 2011;54(1):22-28.   Published online January 31, 2011
Purpose

To investigate the clinical characteristics of late-onset epilepsy combined with autism spectrum disorder (ASD), and the relationship between certain types of electroencephalography (EEG) abnormalities in ASD and associated neuropsychological problems.

Methods

Thirty patients diagnosed with ASD in early childhood and later developed clinical seizures were reviewed retrospectively. First, the clinical characteristics, language and behavioral regression, and EEG findings of these late-onset epilepsy...

Sleep patterns and school performance of Korean adolescents assessed using a Korean version of the pediatric daytime sleepiness scale
Seonkyeong Rhie, Sihyoung Lee, Kyu Young Chae
Clin Exp Pediatr. 2011;54(1):29-35.   Published online January 31, 2011
Purpose

Korean adolescents have severe nighttime sleep deprivation and daytime sleepiness because of their competitive educational environment. However, daytime sleep patterns and sleepiness have never been studied using age-specific methods, such as the pediatric daytime sleepiness scale (PDSS). We surveyed the daytime sleepiness of Korean adolescents using a Korean translation of the PDSS.

Methods

We distributed the 27-item questionnaire, including the PDSS and...

Case Reports
Renal transplantation in a patient with Bartter syndrome and glomerulosclerosis
Se Eun Lee, Kyoung Hee Han, Yun Hye Jung, Hyun Kyung Lee, Hee Gyung Kang, Kyung Chul Moon, Il Soo Ha, Yong Choi, Hae Il Cheong
Clin Exp Pediatr. 2011;54(1):36-39.   Published online January 31, 2011

Bartter syndrome (BS) is a clinically and genetically heterogeneous inherited renal tube disorder characterized by renal salt wasting, hypokalemic metabolic alkalosis and normotensive hyperreninemic hyperaldosteronism. There have been several case reports of BS complicated by focal segmental glomerulosclerosis (FSGS). Here, we have reported the case of a BS patient who developed FSGS and subsequent end-stage renal disease (ESRD) and provided...

A case of tacrolimus-induced encephalopathy after kidney transplantation
Myoung Uk Kim, Sae Yoon Kim, Su Min Son, Yong Hoon Park
Clin Exp Pediatr. 2011;54(1):40-44.   Published online January 31, 2011

We present a case of tacrolimus-induced encephalopathy after successful kidney transplantation. An 11-year-old girl presented with sudden onset of neurologic symptoms, hypertension, and psychiatric symptoms, with normal kidney function, after kidney transplantation. The symptoms improved after cessation of tacrolimus. Magnetic resonance imaging (MRI) showed acute infarction of the middle cerebral artery (MCA) territory in the right frontal lobe. Three days...


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