- Review Articles
- Pathogenesis and clinical manifestations of juvenile rheumatoid arthritis
- Youn-Soo Hahn, Joong-Gon Kim
- Clin Exp Pediatr. 2010;53(11):921-930. Published online November 30, 2010
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Juvenile rheumatoid arthritis (JRA) is the most common rheumatic childhood disease; its onset is before 16 years of age and it persists for at least 6 weeks. JRA encompasses a heterogeneous group of diseases that is classified according to 3 major presentations: oligoarthritis, polyarthritis, and systemic onset diseases. These presentations may originate from the same or different causes that involve...
- Juvenile idiopathic arthritis: Diagnosis and differential diagnosis
- Ki Hwan Kim, Dong Soo Kim
- Clin Exp Pediatr. 2010;53(11):931-935. Published online November 30, 2010
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Juvenile idiopathic arthritis (JIA) is comprised of a heterogeneous group of several disease subtypes that are characterized by the onset of arthritis before the age of 16 years and has symptoms lasting at least 6 weeks. The previous classification of JIA included seven different categories, whereas its current classification was compiled by the International League of the Association for Rheumatology,...
- Treatment of juvenile rheumatoid arthritis
- Kwang Nam Kim
- Clin Exp Pediatr. 2010;53(11):936-941. Published online November 30, 2010
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The systematic approach to pharmacologic treatment is typically to begin with the safest, simplest, and most conservative measures. It has been realized that the more rapidly inflammation is under control, the less likely it is that there will be permanent sequelae. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of initial treatment for inflammation. In addition, the slow-acting antirheumatic drugs (SAARDs)...
- Original Articles
- Analysis of causes of injuries among children in Daegu, Korea
- Geol Ha, Man Joong Jeon, Joon Sakong
- Clin Exp Pediatr. 2010;53(11):942-950. Published online November 30, 2010
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Purpose The purpose of this study was to determine the mechanisms and exact causes of injuries to children by analyzing the medical records of children who visited emergency medical centers.
Methods We reviewed the medical records of 7,114 pediatric patients (aged below 15 years) who visited the emergency care center (ECC) of a Yeungnam university hospital in Daegu between January 2007 and December...
- The role of inhaled and/or nasal corticosteroids on the bronchodilator response
- Ju Kyung Lee, Dong In Suh, Young Yull Koh
- Clin Exp Pediatr. 2010;53(11):951-956. Published online November 30, 2010
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Purpose To compare the profiles of the bronchodilator response (BDR) among children with asthma and/or allergic rhinitis (AR) and to determine whether BDR in these children is reduced by treatment with inhaled and/or nasal corticosteroid.
Methods Sixty-eight children with asthma (mean age, 10.9 years), 45 children with comorbid asthma and AR (mean age, 10.5 years), and 44 children with AR alone (mean age,...
- Prognostic significance of minimal residual disease detected by a simplified flow cytometric assay during remission induction chemotherapy in children with acute lymphoblastic leukemia
- Kyung Nam Koh, Meerim Park, Bo Eun Kim, Ho Joon Im, Chan-Jeoung Park, Seongsoo Jang, Hyun Sook Chi, Jong Jin Seo
- Clin Exp Pediatr. 2010;53(11):957-964. Published online November 30, 2010
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Purpose Our study attempted to determine the prognostic significance of minimal residual disease (MRD) detected by a simplified flow cytometric assay during induction chemotherapy in children with B-cell acute lymphoblastic leukemia (B-ALL).
Methods A total of 98 patients were newly diagnosed with precursor B-ALL from June 2004 to December 2008 at the Asan Medical Center (Seoul, Korea). Of those, 37 were eligible for...
- Survival analysis of spinal muscular atrophy type I
- Hyun Bin Park, Soon Min Lee, Jin Sung Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
- Clin Exp Pediatr. 2010;53(11):965-970. Published online November 30, 2010
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Purpose The life expectancy of patients with spinal muscular atrophy (SMA) type I is generally considered to be less than 2 years. Recently, with the introduction of proactive treatments, a longer survival and an improved survival rate have been reported. In this study, we analyzed the natural courses and survival statistics of SMA type I patients and compared the clinical characteristics...
- Case Reports
- Isolated pulmonary cryptococcosis in an immunocompetent boy
- Siegfried Bauer, Ji Eun Kim, Kyong Suk La, Young Yoo, Kee Hyoung Lee, Sang Hee Park, Ji Tae Choung, Chul Whan Kim
- Clin Exp Pediatr. 2010;53(11):971-974. Published online November 30, 2010
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Pulmonary cryptococcosis is rare in immunocompetent subjects. Here, we present the case of a 16-year-old boy who was referred to our pediatric department for the management of multiple consolidations detected on chest radiography, which was routinely performed when the patient was being evaluated for an ankle fracture. Fine needle aspiration biopsy was performed, and the definitive diagnosis was established as...
- Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
- Sun Ju Park, Dong Kyun Han, Hee Jo Baek, Sang Young Chung, Jong Hee Nam, Hoon Kook, Tai Ju Hwang
- Clin Exp Pediatr. 2010;53(11):975-978. Published online November 30, 2010
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A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PEComa). PEComa in the colon is very rare. Only a few cases have been reported so far. An effective treatment method for...
