- Review Article
- Pulmonology
- Mechanism of resistance acquisition and treatment of macrolide-resistant
Mycoplasma pneumoniae pneumonia in children - Hyeon-Jong Yang, Dae Jin Song, Jung Yeon Shim
- Clin Exp Pediatr. 2017;60(6):167-174. Published online June 22, 2017
-
Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics in Korea occurred in 2006–2007, 2011, and 2015–2016. Although MPP is known to be a mild, self-limiting disease with a good response to macrolides, it can also progress into a...
- Original Articles
- Neonatology (Perinatology)
- Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants
- Jeonghee Shin, Eun Hee Lee, Jee Hyun Lee, Byung Min Choi, Young Sook Hong
- Clin Exp Pediatr. 2017;60(6):175-180. Published online June 22, 2017
-
Purpose Plasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal closure. We investigated the usefulness of serial BNP measurement as a guide for individual identification of early constrictive responses to ibuprofen in preterm infants with symptomatic PDA (sPDA).
Methods Before March 2010, the...
- Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis
- Ji Eun Jeong, Jae Hyun Park, Chun Soo Kim, Sang Lak Lee, Hai Lee Chung, Woo Taek Kim, Eun Joo Lee
- Clin Exp Pediatr. 2017;60(6):181-188. Published online June 22, 2017
-
Purpose Hypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is emerging as a therapeutic candidate for neuroprotection. Therefore, this study was designed to determine the neuroprotective role of recombinant human EPO (rHuEPO) and the possible mechanisms by which mitogen-activated protein kinase (MAPK) signaling pathway including extracellular signal-regulated kinase (ERK1/2), JNK, and p38 MAPK is modulated in...
- Neurology
- Effects of lamotrigine on attention-deficit hyperactivity disorder in pediatric epilepsy patients
- Seung-A Han, Eu Jeen Yang, Mi-Kyoung Song, Sun Jun Kim
- Clin Exp Pediatr. 2017;60(6):189-195. Published online June 22, 2017
-
Purpose The purpose of this study was to investigate the effects of lamotrigine for the treatment of attention-deficit hyperactivity disorder (ADHD) symptoms in children with epilepsy.
Methods Pediatric patients newly diagnosed with epilepsy (n=90 [61 boys and 29 girls]; mean age, 9.1±3.4 years) were enrolled. All patients were evaluated with the Korean ADHD rating scale (K-ARS)-IV before treatment with lamotrigine and after doses...
- Cardiology
- The evolution of electrocardiographic changes in patients with Duchenne muscular dystrophies
- Woo Hyun Yoo, Min-Jung Cho, Peter Chun, Kwang Hun Kim, Je Sang Lee, Yong Beom Shin
- Clin Exp Pediatr. 2017;60(6):196-201. Published online June 22, 2017
-
Purpose Myocardial dysfunction and dysrhythmias are inevitable consequences of Duchenne muscular dystrophy. We aimed to evaluate specific trends of electrocardiographic changes that reflect the progress of cardiomyopathy in patients with Duchenne muscular dystrophy.
Methods Fifty electrocardiograms (ECGs) of 30 patients (ages 1 to 27 years) who had not been prescribed medications for heart failure treatment at the time of examination were retrospectively analyzed...
