- Review Articles
- Gastroenterology
- The role of fecal calprotectin in pediatric disease
- Su Jin Jeong
- Clin Exp Pediatr. 2019;62(8):287-291. Published online March 28, 2019
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Fecal calprotectin (FC) is a calcium- and zinc-binding protein of the S100 family, mainly expressed by neutrophils and released during inflammation. FC became an increasingly useful tool both for gastroenterologists and for general practitioners for distinguishing inflammatory bowel disease (IBD) from irritable bowel syndrome. Increasing evidences support the use of this biomarker for diagnosis, follow-up and evaluation of response to...
- Cardiology
- Reality of Kawasaki disease epidemiology
- Gi Beom Kim
- Clin Exp Pediatr. 2019;62(8):292-296. Published online July 9, 2019
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Epidemiologic studies of Kawasaki disease (KD) have shown a new pattern or change of its occurrence suggestive of its pathophysiology or risk factors from the first patient with KD reported in 1961. The incidence of KD in Northeast Asian countries including Japan, South Korea, China, and Taiwan is 10–30 times higher than that in the United States and Europe. Knowing...
- Editorials
- Cardiology
- Can iron be a risk factor for coronary lesions in Kawasaki disease?
- Kyung Lim Yoon
- Clin Exp Pediatr. 2019;62(8):297-298. Published online June 7, 2019
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- Allergy
- Why should we monitor for hematologic adverse drug reactions to oxcarbazepine?
- Gwang Cheon Jang
- Clin Exp Pediatr. 2019;62(8):299-300. Published online June 24, 2019
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- Original Articles
- Cardiology
- Iron deficiency anemia as a predictor of coronary artery abnormalities in Kawasaki disease
- Sohyun Kim, Lucy Youngmin Eun
- Clin Exp Pediatr. 2019;62(8):301-306. Published online February 8, 2019
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Purpose: Coronary artery abnormalities (CAA) are the most important complications of Kawasaki disease (KD). Iron deficiency anemia (IDA) is a prevalent micronutrient deficiency and its association with KD remains unknown. We hypothesized that presence of IDA could be a predictor of CAA. Methods: This retrospective study included 173 KD patients, divided into 2 groups according to absence (group 1) and presence...
- Neonatology (Perinatology)
- The relation between serum levels of epidermal growth factor and necrotizing enterocolitis in preterm neonates
- Heba Mostafa Ahmed, Nsreen Mostafa Kamel
- Clin Exp Pediatr. 2019;62(8):307-311. Published online March 15, 2019
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Purpose: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a major role in intestinal barrier function, increases intestinal enzyme activity, and improves nutrient transport. The aim of this study was to assess the role of epidermal growth factor in the...
- Neurology
- Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine
- Gu Hyun Jung, Su Jeong You
- Clin Exp Pediatr. 2019;62(8):312-316. Published online April 11, 2019
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Purpose: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the rate and types of the hematologic side effects of OXC. Methods: The medical records of 184 patients diagnosed with epilepsy or movement disorder and on OXC monotherapy, at the Department of...
- General Pediatrics
- Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: analysis based on the 2016–2017 Korea National Health and Nutrition Examination Survey
- Jung Hyun Lee
- Clin Exp Pediatr. 2019;62(8):317-323. Published online June 24, 2019
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Purpose: Investigating the prevalence of hyperuricemia and its association with metabolic syndrome (MetS) and cardiometabolic risk factors (CMRFs) in Korean children and adolescents. Methods: This cross-sectional survey used data from the 7th Korea National Health and Nutrition Examination Survey (2016–2017); 1,256 males and females aged 10–18 years were included. Hyperuricemia was defined as serum uric acid levels were >6.6 mg/dL at...
