All issues > Volume 35(2); 1992

Original Article

J Korean Pediatr Soc. 1992;35(2):211-218. Published online February 15, 1992.

Thrombocytosis in Childhood

Seung Wan SW Lee¹, Young Jin YJ Hong¹, Soon Wha SW Kim¹, Don Hee DH Ahn¹

¹Department of Pediatrics, National Medical Center, Seoul, Korea

Abstract

Hundred and twenty five cases of thrombocytosis were observeed at National Medical Center between Jan. lst 1989 and June 30, 1990. The results were as follows; 1) In thrombocytosis, sewual difference was not noticed(61 male and 50 female children). 2) Age distributed from newborns to 15 years of age with median age of 5 months. 3) The platelet counts ranged from 750 to 1650×103 m㎥ : With 112 counts less than and 13 counts greater than 1000×103 m㎥. 4) Conditions associated with thrombosytosis were as follows. Infection was the most common cause of thrombocytosis(45.6%), followed by respiratory (10.4%), traumatic (9.6%), renal (8.8%), hematologic (8%), collagen vascular disease (8%), neoplatic (4.8%) and miscellaneous (4.8%) in the order of frequency. The most common infectious cause of thrombocytosis involved the respiraltory system (45.6%) followed by urinary tract (24.6%), intestinal (8.9%), CNS (5.3%) and miscelloneous (17.7%) in the order of frequency. 5) There were 13 cases that platelet counts exceeded 1000×103 m㎥ : MCLS (3 episodes), bacterial meningitis (2 episodes), CML (2episodes), surgery (2 episodes), viral pneumonia (1 episode), croup (1 episode), IDA (1 episodes), ulcercative colitis (1 epidose) etc. 6) Thrombocytosis seldom persisted, the platlet count decreased to less than the 750×103 m㎥level after median of 1 week (range 1 to 23 day) with only two episodes persisting for more than 40days, all of these being in the patient of CML. 7) Reactive thrombocytosis associated with leukoytosis were noted in 34 episodes (27.2%). 8) Lows Hb level for his or her age wre 47 episodes (37.6%).

Keywords :Thrombocytosis, Childrehood