All issues > Volume 35(2); 1992

Original Article

J Korean Pediatr Soc. 1992;35(2):226-233. Published online February 15, 1992.

Clincal Observations on Human Rotavirus (HRV) Gastroenteritis

Seung Ryong SR Han¹, Seung Hyun SH Seo¹, Ki Sik KS Min¹, Jong Wan JW Kim¹, Kwang Nam KN Kim¹, Ki Yang KY Ryoo¹

¹Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea

Abstract

Clinical observations were made on 787 patients who were admitted to pediatric department of Kangdong Sacred Heart hospital because of watery diarrhea and vomiting between Jan. 1987 and Dec, 1989. ELISA study was done to detect HRV antigen for all patients. The results were as follows : 1) HRV antigen was detected in 492 patients (62.5%) by ELISA among 787 patients with watery diarrhea and vomiting. 2) Out of 192 patients who had HRV antigen, 409 patients (83.1%) were between 6~24 months of age. Most of the patients were seen durng cold seasons in autumn (57.1%) and winter (26.6%). 3) The mean duration of hospitalization was 5.4¡¾1.8 days in HRV gastroenteritis and 5.5¡¾2.1 days in non-HRV gastroenteritis. 4) The frequency of diarrhea less than 6 times per day was 67.3%(331/492) in HRV gastroenteritis and 67.8% (200/295) in non-HRV gastroenteritis. There was no difference in frequency of diarrhea between two groups. 5) In addition to diarrhea, the major symptoms in order of frequency were vomiting(79.9%), fever (45.7%), and coughing(22.8%) in HRV gastroenteritis, and vomiting( 53.6%), fever (50.5%), and coughing (31.5%) in non-HRV gastroenteritis. The incidence of vomiting in HRV gastroenteritis was higher than in non-HRV gastroenteritis (p<0.05). 6) AST elevation above normal was significantly increased in HRV gastroenteritis than non-HRV gastroenteritis (p<0.05). but ALT elevation between two groups was not correlated statistically. 7) Mean concentration of AST was significantly increased in HRV gastroenteritis than non-HRV gastroenteritis (p<0.05). but mean concentration of ALT between two groups was not correlated statistically.

Keywords :Human Rotavirus, Gastroenteritis