All issues > Volume 35(3); 1992

Original Article

J Korean Pediatr Soc. 1992;35(3):330-341. Published online March 15, 1992.

The Clinical Observation in Kawasaki Disease

Young Jin YJ Jang¹, Joong Gon JG Kim¹, Yong Soo YS Yun¹

¹Department of Pediatrics, Seoul National University College of Medicine, Seoulk, Korea

Abstract

The one-hundred thirty five cases with Kawasaki disease who wre diagnosed and treated at the department of pediatrics, Seoul National University Children뭩 Hospital from September 1984 to December 1990, were investigated for clinical pattrns and laboratory correlations. The results were as follows; 1) Most patients (86%) were under 4 years of the age. 2) boys wee more prevalent than girls, as a ratio of 1.8:1. 3) The incidence of principal symtoms were fever over 5 days (95%), bilatral conjunctival injection (96%), lip and oral mucosa change (93%), skin eruption (90%), cervical lymphadenopathy (83%), changes in extremities (indurative edema or erythema of hands and feet (57%), desquamation (69%). 4) The main laboratory findings observed were positive CRP (96%), increased peak level of ESR (91%), thrombocytosis (88%), leukocytosis (74%), anemia (25%), increased SGOT (18%), increased SGPT (23%), proteinuria (1%), pyuria (21%), microscopic hematuria (1%). 5) The abnormalities of chest P-A were 34%, that of electrocardiography were 34% and coronary aneurysm by echocardiography was found in 49% of examed cases, among which regressed cases was 36%. 6) Abdominal ultrasonography showed gallbladder hydrops (56%). 7) Coronary aneurysm developing group compared with non-developing group was that age of onset was younger, male was moe prevalent, duration of fever was longer, peak WBC count was higher, and duration of abnormal CRP was longer. There were more cases which duration of fever was more than 16 days and duration of abnormal CRP was 30 days in coronary aneurysm developing group. 8) Coronary aneurysm rgressing group compared with non-regressing group was that duration of fever was longer, peak platelet count was higher, duration of abnormal CRP was longer, and there was more cases which anemia was present.

Keywords :Kawasaki disease