All issues > Volume 35(4); 1992

Original Article

J Korean Pediatr Soc. 1992;35(4):508-514. Published online April 15, 1992.

A Study of Serologically Confirmed Measles

Sang Mook SM Choi¹, Chang Soo CS Oh¹, Sang Chul SC Park¹, Chang Hwi CH Kim¹, Sang Jhoo SJ Lee¹

¹Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea

Abstract

Forty one cases of serologically confirmed measles(positive measles specific IgM antibody) were evaluated among 55 cases of clinically diagnosed measles admitted to Soon Chun Hyang University Hospital from May to August 1990. The results were as follows: 1) Sex ratio was 1.6 : 1 with male predominance in 41 cases, 13 cases(31.7%) were vaccinated and 28 cases(68.3%) were unvaccinated. Primary vaccine failure was presumed to be the cause of measles in the 13 vaccinated cases(31.7%). 2) Among the 22 cases(53.7%) under 15 months of age, 14 cases(34.1%) were under 9 months of age. 3) Fever, rash and cough were noted in all of the cases, but Koplik spot was noted in only 2 9 cases. 4) The most common complication was pneumonia(68.5%). 5) Among the 55 cases of clinical measles, 32 cases were evaluated simultaneously for measles specific IgM and IgG antibodies. Measles specific IgM antibody was detected in 20 cases, with 6 cases in the vaccinated group and 14 cases in the unvaccinated group. Among the 20 cases, showing positive measles specific IgM antibody, measles specific IgG antibody was also detected in 5 of 6 cases in the vaccinated group, whereas 6 of the 14 cases in the unvaccinated group.

Keywords :Measles Specific IgM Antibody