All issues > Volume 35(4); 1992

Case Report

J Korean Pediatr Soc. 1992;35(4):539-544. Published online April 15, 1992.

A Case of Congenital Dyserythropoietic Anemia

Il Tae IT Whang¹, Young Sook YS Ko¹, Kyeung Hee KH Kim¹, Gyeung In GI Lee², Han Ik HI Cho³

¹Department of Pediatrics, College of Medicine, Ewah Womans University, Seoul, Korea
²Department of Pathology, College of Medicine, Ewah Womans University, Seoul, Korea
³Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea

Abstract

Congenital dyserythropoietic anemia(CDA) is a rare disease characterized by ineffective erythropoiesis, specific cytopathology of the nucleated red cells in the bone marrow and secondary hemochromatosis. CDA is classified into 4 types on the basis of results of electron microscopic and serologic studies. We experienced a case of congenital dyserythropoietic anemia in a 5/12 year-old boy. Diagnosis was established by macrocytosis, anisopoikilocytosis in PB smear and megaloblastoid change in BM findings. A brief review of related literatures was made.

Keywords :Congenital dyserythropoietic anemia