All issues > Volume 35(5); 1992

Original Article

J Korean Pediatr Soc. 1992;35(5):659-666. Published online May 15, 1992.

MIC and MBC of Oral Antimicrobial Agents Against Staphylococcus aureus

Min Hang MH Kim¹, Jin Won JW Park¹, Yun Joo YJ Chung¹, Kyung Sik KS Ryoo², Myung Woong MW Chang²

¹Department of Pediatrics, Kosin Medical College, Pusan, Korea
²Department of Microbiology, Kosin Medical College, Pusan, Korea

Abstract

Antimicrobial susceptibility for 25 stranis of methicillin senitive Staphylococcus (MSSA) and 25 strains of methicillin resistant Staphylococcus aureus (MRSA), isolated from in-patients at Kosin Medical Center from January, 1989 to July, 1990, were tested by the tube dilution method. 1) For MSSA, sensitivity tests showed 21% was sensitive to cefadroxil. Seventy one percent was intermediate and 8% was resistant. 2) 96% of MSSA was sensitive to methicilline, 79% of MSSA was sensitive to oxacillin and 59% of MSSA was sensitive to amoxacillin/clavulanic acid. 3) 92% of MSSA was sensitive to trimethoprim/sulfamethoxazole while 44% of MRSA was sensitive to the drug and 52% was intermediate. 4) All MRSA stains were resistant to methicillin, oxacillin, amoxacillin/clavulanic acid and cefadroxil. 5) Trimethoprim/sulfamethoxazole may be used for MRSA infection.

Keywords :Sensitivity to antibioctics, Staphylococcus aureus