All issues > Volume 35(7); 1992

Case Report

J Korean Pediatr Soc. 1992;35(7):989-994. Published online July 15, 1992.

A Case of Addison's Dlisease

Baek Gil BG Lee¹, Hyang Sook HS Lee¹, Il Kyung IK Kim¹, Ho H Sung¹, Chang Hee CH Choi¹

¹Department of Pediatrics, Seoul Adventist Hospital, Seoul, Korea

Abstract

A 14-year-old Korean boy with Addison's disease probably of tuberculosis origin is presented with a brief review of the literature. The patient was admitted to our hospital on July, 23th, 1990, because of dark brown pigmentation of the skin, mucous membrane and nail beds. On physical examination, he was moderately developed, relatively poorly nourished. Skin and mucous membranes were diffusely dark brown, especially over the face, gingiva, tongue, both elbow and nail beds of hands and feet. Laboratory studies showed neutropenia, relative lymphocytosis, low serum cortisol, high ACTH concentration and low 24 hours urinary 17-OHCS. ACTH stimulation test(rapid I.M. ACTH TEST) failed to rise the plasma cortisol level.

Keywords :Addison's disease, Chronic adrenal insuffciency