All issues > Volume 35(7); 1992

Case Report

J Korean Pediatr Soc. 1992;35(7):1014-1018. Published online July 15, 1992.

A Case of Distal Type of Renal Tubular Acidosis in a Neonate

Sung Sub SS Shim¹, Young Joon YJ Kim¹, Jae Hong JH Park¹, Soo Yung SY Kim¹, Chan Yung CY Kim¹

¹Department of Pediatrics, Pusan National University College of Medicine, Pusan, Korea

Abstract

A female infant at 38 days of age was admitted to pediatric department of Pusan National University hospital due to dehydration, weight loss, vomiting, polyuria. Physical exmination at the time of admission revealed a slightly anemic, moderately dehydrated, dwarfed female infant in no acute distress. Laboratory studies on admission revealed hypokalemic, hyperchloremic metablic acidosis with normal anion gap and persistent high urine pH. Ultrasonography and computed tomo-graphy of kidney showed bilateral nephrocalcinosis. Urinary bicarbonate fractional excretion demonstrated 5.28% urinary leak of filtred load during sodium bicarbonate infusion over a plasma bicarbonate range of 15 to 25 mEq/liter. The above results suggested distal renal tubular acidosis. After 2 weeks of potassium and alkali replacement therapy, she had improved the clinical symptoms and laboratory findings, but remained nephrocalcinosis radiologically. With the reveiw of literatures, the case is presented.

Keywords :Renal tubular acidosis, Distal type