All issues > Volume 35(12); 1992

Case Report

J Korean Pediatr Soc. 1992;35(12):1750-1755. Published online December 15, 1992.

A Case of Congenital Neuroblastoma: Diagnosed at Antenatal Perio

Hye Young HY Kang¹, Chuhl Joo CJ Lyu¹, Byung Soo BS Kim¹, Seung Kang SK Choi², Woo Hee WH Jung³, Soon Ae SA Chun⁴

¹Department of Pediatrics, Yonsei University, College of Medicine, Yonsei Cancer Center, Seoul, Korea
²Department of Urology, Yonsei University, College of Medicine, Seoul, Korea
³Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea
⁴Department of Radiology, Banwol Hospital, Banwol, Korea

Abstract

Neuroblastoma is one of the most common tumors of childhood. It accounts for about 8% of all pediatric cancers. Because most children who present with this tumor are older than 1 year of age and have advanced disease, they have a poor prognosis in spite of intensive treatment. The patients with less than 1 year of age at the time of diagnosis a have favorable prognosis, even though they have distant metastasis to liver, skin and/or bone marrow with stage I or II. For the improvement in survival of patient with neuroblastoma, early detection of subclinical tumor is very important. However, it is very rare for neuroblastoma to be detected during intrauterine period and confirmed pathologically after birth as shown in this case. We experienced a case of 2 month-old-male baby who was suspected of neuroblastoma by antenatal sonographic examination at IUP 38 weeks, which was confirmed by postoperative pathological findings. The tumor was excised completely. The patient was closely observed for one and a half years and there were no evidence of recurrence. We report this case and review related literatures briefiy.

Keywords :Congenital Neuroblastoma, Diagnosed at during intrauterine period