All issues > Volume 36(3); 1993

Case Report

J Korean Pediatr Soc. 1993;36(3):403-408. Published online March 15, 1993.

Changes of Serum IgG4 in Allergic Patients

Soo Young SY Cho¹, Sun Kyu SK Park¹, Pyoung Han PH Hwang¹, Jung Soo JS Kim¹

¹Department of Pediatrics, Chonbuk National University Medical School, Chonju, Korea

Abstract

This study ws performed to evaluate the changes of serum IgG4 level in children with allergic diseases. Serum IgE, IgG and IgG4 level were measured using enyzme immunoassay(IgE) and radial immunodiffusion method (IgG and IgG4) in 21 children with bronchial asthma, allergic rhinitis or urticaria. Eosinophil counts in peripheral blood and the values fo serum IgE were significantly increased in allergic patients. The values of IgG4 in allergic patients were also increased compare to those in controls(24.23mg/dl versus 20.33mg/dl). But the values of IgG4 were not significantly correlated to either IgG r IgE levels.Further studies will be needed for measuring allergen specific IgE and IgG4 levels considering the onset of diseases, methods and duration of treatment.

Keywords :Allergy, IgG4