All issues > Volume 36(6); 1993

Original Article

J Korean Pediatr Soc. 1993;36(6):842-849. Published online June 15, 1993.

Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990

Young Ah YA Lee¹, Sei Ho SH Oh¹, Soo Jong SJ Hong¹, Young Hwue YH Kim¹, Hyung Nam HN Moon¹, Chang Yee CY Hong¹

¹Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea

Abstract

We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990. The results were as follows; 1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%) 2) The male-to-female ratio of HFMD was 2.03 to 1, but that of aseptic meningitis was 8 to 1. 3) Hand, Foot and mouth disease occureed more frequently in under the age of 5 years, and the aseptic meningitis in under the age of 1 year. 4) Hand, foot and mouth disease and the aseptic meningitis occureed mostly in May and June 5) In addition to the skin maifestations characteristic in hand, foot and mouth disease, some of the patients with aseptic meninitis han the following symptoms: change of consiousness, seizure, monoparesis in the upper extrmity, paraparesis in the lower extremity. 6) The causative agent of hand, foot and mouth disease associated with the aseptic meningitis in Seoul in 1990 seemed to be enterovirus 71 according to the serologic study.

Keywords :Hand, foot and mouth disease, Aseptic meningitis, Enterovirus 71