All issues > Volume 36(6); 1993

Case Report

J Korean Pediatr Soc. 1993;36(6):877-881. Published online June 15, 1993.

A Case of Unialteral Megalencephaly

Woo Seok WS Kim², Nam Soo NS Park², Moo Young MY Song², Un Jun UJ Hyoung², Jin Oh JO Lee², Yong Seung YS Hwang¹

¹Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
²Department of Pediatrics, Sung Ae General Hospital, Seoul, Korea

Abstract

The unilateral megalencephaly is a rare brain malfromation characterized by cerebral asymmetry and cortical dysplasia caused by faulty migration of the subependymal neuroblasts. We experienced a case of unilateral megalencephaly in a two day-old male with the chief complaint of asymmetric head appearance. Large left hemisphere with agyria, pachygyria. dilatation of lateral ventricle, and the thick cortex of the ipsilteral hemisphere were showed in brain MRI. Coinical findings in the case were intractable seizure, hemiparesis, and psychomotor retardatism. A review of literatures was also presented briely.

Keywords :Unilateral megalencephaly