All issues > Volume 37(1); 1994

Original Article

J Korean Pediatr Soc. 1994;37(1):54-60. Published online January 15, 1994.

A Clinical Observation of Neonatal Hyperbilirubinemia Due to ABO imcompatibility

Kang Woo KW Lee¹, Young Guk YG Kim¹, Dong Gun DG Park¹, Kee Hwan KH Yoo¹, Kwang Chul KC Lee¹, Soon Kyum SK Kim¹

¹Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea

Abstract

A clinical and statistical study was performed on 213 neonates of hyperbilirubinemia who were admitted to department of pediatrics of Korea University Hospital from Jan. 1989 to Jun. 1991. And we studied the difference between ABO compatible group and incompatible group, such as, day of appe5rance of hyperbilirubinemia, tendency of bilirubin concentration change, reticulocyte, hemoglobin and duration of hyperbilirubinemia. The following results were obtained. 1) There were no difference of initial body weight and gestational age between compatible (3.0¡¾0.72kg, 382. ¡¾3.2weeks) and incompatible groups(3.2¡¾0.54kg, 39.1¡¾2.8weeks). 2) Onset of hyperbilirubinemia within 2days in the imcompatible group (40.5%) was earlier than the compatible group (23.5%) significantly (p<0.05). 3) Mean bilirubin level in the imcompatible gropu was higher than the compatible group significantly (p<0.05). 4) Peak bilirubin level in the imcompatible group (18.7¡¾4.1mg/dl) was higher than the compatible group (14.8¡¾3.4mg/dl) significantly (p<0.05). 5) There were no difference of hemoglobin level, reticulocyte count, coombs positive findings and the ratio of exchange transfusion between two gropus.

Keywords :ABO Incompatibility, Hyperbilirubinemia