All issues > Volume 37(8); 1994

Original Article

J Korean Pediatr Soc. 1994;37(8):1104-1110. Published online August 15, 1994.

A Clinical and Pathological Study of Recurrent Hematuria in Childhood

Mi Jeong MJ Kim¹, Jae Wook JW Ko¹, Young Jin YJ Hong¹, Myung Ik MI Lee¹, Sun Wha SW Kim¹, Don Hee DH Ahn¹

¹Department of Pediatrics, National Medical Center, Seoul, Korea

Abstract

The clinico-pathological observation was done on 28 children with recurrent hematuria, who had been admitted to the Pediatric ward of NMC from January 1981 to July 1991. The results were as follows; 1) Most of the children with recurrent hematuria were over 6 years of age (24 cases, 85.7%) and the sex ratio was about 2.5:1. 2) IgA nephropathy (17 cases, 60.7%) was the leading pathologic lesion and mild focal nonspecific glomerulonephritis (5 cases), membranous nephropathy (2 cases), minimal chage (2 cases), Alport syndrome (1 case), abnormal glomerular basement membrane (1 case) followed. 3) Types of recurrent hematuria were gross in 22 cases and microscopic in 6 cases. Flank pain was noted only 1 case. The prodromal events of hematuria were upper respiratory infection in 15 cases and severe exercise in 2 cases. 4) There were no significant differences in clinical features and laboratory findings between IgA nephropathy and other pathologic lesions, except for higher frequency of proteinuria in former group. 5) During the follow-up periods, three cases were resulted in chronic renal failure and they were two cases of IgA nephropathy Class IV and one case of Alport syndrome. And one case of IgA nephropathy was resulted in nephrotic syndrom.

Keywords :Recurrent hematuria, IgA nephropathy