All issues > Volume 37(9); 1994

Original Article

J Korean Pediatr Soc. 1994;37(9):1235-1244. Published online September 15, 1994.

A Clinical Study of Childhood Systemic Lupus Erythematosus

Young-Jun YJ Kim¹, Young Don YD Kim¹, Jae Hong JH Park¹, Su Young SY Kim¹, Hee-Ju HJ Park¹

¹Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea

Abstract

To Evaluate the clinical characteristics of childhood-onset systemic lupus erythemoatosus (SLE) and analyse the factors related to outcome of renal function in lupus nephritis, we reviewed medical records of 18 cases of SLE diagnosed at the Department of Pediatrics, Pusan Nationsl University Hospital from January 1981 to December 1990. The results were as was 1:2.6 1)Male to female ratio was 1:2.6. 2)Nephropathy was the most common initial impression, and 8 cases were diagnosed as SLE at first. 3)The clinical menifestation was ANA(+), malar rash, renal disorder, hematologic disorder in frequency. 4)Diffuse proliferative lupus nephritis was the most common in renal histopathologic studies. 5)Among the follow-up cases, active lupus was 39%, remission was 28%. 6)As factors related to outcome of lupus nephrits were, hypertension and proteinuria were siginificant statistically.

Keywords :Systemic Lupus Erythematosus