All issues > Volume 37(9); 1994

Original Article

J Korean Pediatr Soc. 1994;37(9):1257-1263. Published online September 15, 1994.

The Role of Urinary Sodium at Transient Renal Acidification Defect during Acute Infantile Actue Gastroenteritis

Abstract

The pupose of this study is to verify the role of urinary sodium in transient renal acidification defect which frequently combine acute infantile gastroenteritis. We studied on twenty-five infants, 2 month to 36 month of age, during the 4 month period, from August, 1991 to December, 1991. The patients had acidosis for a mean of 3 days and sixty urine samples were collected during this period. The mean pH of 23 urine samples with sodium concentration<10 mmol/L was significantly higher than the pH of 37 samples with sodium concentration<10 mmol/L, We separately analyzed 15 urine samples collected during metabolic acidosis after completion of rehydration. The result was that a urinary acidification defent was observed in the urine samples with low sodium concentration but not in the sodium rich samples We concluded that impaired urinary acidification defect is frequently found during metabolic acidosis in infants with acute gastroenteritis and results from a sodium deficit rather than from transient distal renal tublur acidosis.

Keywords :Renal acidification defect, Urinary sodium excretion