All issues > Volume 37(10); 1994

Original Article

J Korean Pediatr Soc. 1994;37(10):1333-1339. Published online October 15, 1994.

Airway Resistance after Exercise Loading Test in Asthmatic Children

Ji Eun JE Lee¹, Young Mi YM Hong¹, Kyung Hee KH Kim¹

¹Department of Pediatrics, Ewah Womans University Hospital, Seoul, Korea

Abstract

Exercise induced asthma(EIA) is defined as acute, reversible, usually self-immiting airway obstruction which develop after strenous exercise in patients with asthma. EIA is a bigger problem in children than adults due to more active and smaller airways which obstruct more easily when bronchospasm develops. The exercise elicited amny change in pulmonary function of asthmatic children. These change could be measured by measurements of PEFR, FEV1, FVC, or Sraw. The propose of this study is to determine the changes and sensitivity of different pulmonary function test in asthmatic children. 37 asthmatic children exercised on free running and pulmonary function tests were perfomed before and every 5 minutes during 15 minutes after exercise. The results were as follows. 1) In 37 asthmatic children, EIA developed in 23 children(62%) and did not developed in 14 children (38%). The difference in sex, height, weight, total eosinophil count, serum IgE and test between EIA and Non-EIA were not significan(p> 0.05). 2) In EIA group, %PEFR was changed from 109.56% to 83.56%, But in Non-EIA group, %PEFR was not changed before and after exercise loading test. 3) In EIA group, %FEV1 was changed from 90.91% to 74.87%. But in Non-EIA group, %FEV1 was not changed berfore and after exercise loading test. 4) In EIA group, %FEV changed from 91.83% to 75.35%. But in Non-EIA group, %FVC was not changed berfore and after exercise loading test. 5) There was significant difference in pre-exercise specific airway resistance between EIA(6.7¡¾1.7) and normal children(5.8¡¾2.2)(p<0.05). In EIA group, %Sraw was changed from 115.7% to 161.2%. But in Non-EIA group, %Sraw was not changed before and after exercise loading test. 6) During the post-exercise observation period, increasement of Sraw was greater than changes in any other pulmonary function test. Sraw is the most sensitive test for the ditection of exercise induced airway obstruction is asthmatic children.

Keywords :Exercise loading test, Specific airway resistance, Asthma