All issues > Volume 38(6); 1995

Erratum

J Korean Pediatr Soc. 1995;38(6):857-862. Published online June 15, 1995.

Vertical Transmission of Hepatitis C Virus in Infant of the Mother Who Had Active Hepatitis C during Pregnancy

Mi-Jeong MJ Lee¹, Mi-Jeong MJ Lee²

¹Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea
²Department of Clinical Pathology, Korea Cancer Center Hospital, Seoul, Korea

Abstract

Vertical transmission of hepatitis C virus(HCV) has been reported recently. The authors experienced one case of vertical transmission of HCV in infant of the mother who had active hepatitis C durig pregnancy. At delivery, HCV RNA(+), IgG anti HCV Ab(+), IgM anti HCV Ab(+), mile elevation of liver aminotransferase level and mile fatty liver of ultrasonography were found in the mother. At birth HCV RNA(+) and IgG anti HCV Ab(+) were found in the baby. HCV RNA(+), IgG anti HCV Ab(+) and IgM anti HCV Ab(+) were noted on the day 107 in the serum of the infant. We used reverse transcriptase polymerase chain reaction(RT-PCR) technique to find very small amount of HCV RNA in the serum. All those findings suggest vertical transmission of HCV from mother to infant.

Keywords :Hepatitis C virus, Vertical transmission, Reverse transcriptase polymerase chain reaction